Efficacy of Nirmatrelvir/ritonavir in reducing the risk of severe outcome in patients with SARS-CoV-2 infection: a real-life full-matched case-control study (SAVALO Study) - Gentile, Ivan; Giaccone, Agnese; Scirocco, Maria Michela; Di Brizzi, Francesco; Cuccurullo, Federica; Silvitelli, Maria; Ametrano, Luigi; Alfè, Francesco Antimo; Pietroluongo, Daria; Irace, Irene; Chiariello, Mariarosaria; De Felice, Noemi; et al. (BMC infectious diseases, 2024)
Keywords: Adult; Aged; Antiretroviral drugs; Antiviral Agents - therapeutic use; Antiviral drugs; Cardiovascular disease; Case studies; Case-Control Studies; Chronic obstructive pulmonary disease; Comorbidity; COVID-19; COVID-19 - epidemiology; COVID-19 - mortality; COVID-19 Drug Treatment; COVID-19 vaccines; Diabetes; Disease transmission; Dosage and administration; Drug Combinations; Drug therapy, Combination; Early treatment; Effectiveness; Female; Health services; HIV; Hospitalization - statistics & numerical data; Hospitals; Human immunodeficiency virus; Humans; Hypertension; Immune system; Immunity (Disease); Infectious diseases; Italy - epidemiology; Kidney diseases; Lopinavir - therapeutic use; Lung diseases; Male; Middle Aged; Monoclonal antibodies; Mortality; Nirmatrelvir/ritonavir; Patient outcomes; Patients; Performance evaluation; Public health; Ritonavir; Ritonavir - therapeutic use; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Treatment Outcome; Tumor necrosis factor-TNF; Vaccination; Variables; Viral diseases; Italy; COVID-19; SARS-CoV-2; Nirmatrelvir/ritonavir; Early treatment; Mortality