universal distribution of evolutionary rates of genes and distinct characteristics of eukaryotic genes of different apparent ages

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 106; no. 18; pp. 7273 - 7280
• Main Authors: Wolf, Yuri I, Novichkov, Pavel S, Karev, Georgy P, Koonin, Eugene V, Lipman, David J
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 05.05.2009; National Acad Sciences
• Series: Inaugural Article
• Subjects: Age structure; Animals; Aspergillus; Biological evolution; Biological Sciences; Correlation analysis; Diptera; Divergent evolution; Eukaryotes; Eukaryotic Cells - metabolism; Evolution; Evolution, Molecular; fungi; gene deletion; Gene Transfer, Horizontal; Genes; Genome; Genomes; Genomics; Humans; introns; lognormal distribution; Mammals; Mathematical models; Models, Genetic; phylogeny; prokaryotic cells; Proteins; Proteins - genetics; Wolves

The evolutionary rates of protein-coding genes in an organism span, approximately, 3 orders of magnitude and show a universal, approximately log-normal distribution in a broad variety of species from prokaryotes to mammals. This universal distribution implies a steady-state process, with identical d...