Mechanisms of microRNA-mediated gene regulation in animal cells

• Published in: Trends in genetics Vol. 23; no. 5; pp. 243 - 249
• Main Author: Nilsen, Timothy W.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.05.2007; Elsevier Science
• Subjects: Animals; Biological and medical sciences; Caenorhabditis elegans - cytology; Caenorhabditis elegans - genetics; Drosophila melanogaster - cytology; Drosophila melanogaster - genetics; Forecasting; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation; Genetics of eukaryotes. Biological and molecular evolution; Medical Education; MicroRNAs - genetics; MicroRNAs - metabolism; Models, Genetic; Molecular and cellular biology; RNA Processing, Post-Transcriptional; RNA, Messenger - genetics; RNA, Messenger - metabolism; Transcription, Genetic; Regulation(control); RNA interference; Gene; Animal; Micro RNA; Genetics; Mechanism

MicroRNAs are a large family of regulatory molecules found in all multicellular organisms. Even though their functions are only beginning to be understood, it is evident that microRNAs have important roles in a wide range of biological processes, including developmental timing, growth control, and d...