Alexithymia in healthy women: A brain morphology study
Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults. Fifty-fo...
Saved in:
| Published in | Journal of affective disorders Vol. 114; no. 1; pp. 208 - 215 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford
Elsevier B.V
01.04.2009
Elsevier |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0165-0327 1573-2517 1573-2517 |
| DOI | 10.1016/j.jad.2008.07.013 |
Cover
Loading…
| Abstract | Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults.
Fifty-four female volunteers were enrolled in the study and the 20-item Toronto Alexithymia Scale (TAS-20) was self-administered. Gray matter (GM) volume was assessed with an optimized voxel-based morphometry (VBM) protocol on high-resolution 3D magnetic resonance images. The following three experiments were carried out: 1) contrast between the 14 volunteers with TAS-20 scores
≥
61 (alexithymic) and the 30 with scores <
51 (non-alexithymic), 2) correlation of TAS-20 scores on the whole sample and 3) contrast between the 14 alexithymic and 14 non-alexithymic matched by age. The significant threshold for VBM comparisons and correlation was set at
p
<
0.005 uncorrected.
The alexithymic group showed smaller GM volume in the anterior cingulate cortex (cluster size: 735 voxel no.;
z
=
3.26; stereotaxic coordinates: −
12, 22, 30) and middle temporal gyrus (256; 3.21; −
60, 2, −
20). Of specific biological relevance, smaller clusters were located in the anterior insula, orbitofrontal cortex and superior temporal sulcus. The opposite comparison was negative. The correlation analysis confirmed the pattern of results mainly in the left hemisphere.
Our findings suggest that the ability to process emotional aspects of the self correlates with morphology of a specific set of cerebral structures known to be involved in decision making and self awareness and rich in neurons subserving social competence. |
|---|---|
| AbstractList | Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults.
Fifty-four female volunteers were enrolled in the study and the 20-item Toronto Alexithymia Scale (TAS-20) was self-administered. Gray matter (GM) volume was assessed with an optimized voxel-based morphometry (VBM) protocol on high-resolution 3D magnetic resonance images. The following three experiments were carried out: 1) contrast between the 14 volunteers with TAS-20 scores
≥
61 (alexithymic) and the 30 with scores <
51 (non-alexithymic), 2) correlation of TAS-20 scores on the whole sample and 3) contrast between the 14 alexithymic and 14 non-alexithymic matched by age. The significant threshold for VBM comparisons and correlation was set at
p
<
0.005 uncorrected.
The alexithymic group showed smaller GM volume in the anterior cingulate cortex (cluster size: 735 voxel no.;
z
=
3.26; stereotaxic coordinates: −
12, 22, 30) and middle temporal gyrus (256; 3.21; −
60, 2, −
20). Of specific biological relevance, smaller clusters were located in the anterior insula, orbitofrontal cortex and superior temporal sulcus. The opposite comparison was negative. The correlation analysis confirmed the pattern of results mainly in the left hemisphere.
Our findings suggest that the ability to process emotional aspects of the self correlates with morphology of a specific set of cerebral structures known to be involved in decision making and self awareness and rich in neurons subserving social competence. Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults.BACKGROUNDAlexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults.Fifty-four female volunteers were enrolled in the study and the 20-item Toronto Alexithymia Scale (TAS-20) was self-administered. Gray matter (GM) volume was assessed with an optimized voxel-based morphometry (VBM) protocol on high-resolution 3D magnetic resonance images. The following three experiments were carried out: 1) contrast between the 14 volunteers with TAS-20 scores > or = 61 (alexithymic) and the 30 with scores < 51 (non-alexithymic), 2) correlation of TAS-20 scores on the whole sample and 3) contrast between the 14 alexithymic and 14 non-alexithymic matched by age. The significant threshold for VBM comparisons and correlation was set at p<0.005 uncorrected.METHODSFifty-four female volunteers were enrolled in the study and the 20-item Toronto Alexithymia Scale (TAS-20) was self-administered. Gray matter (GM) volume was assessed with an optimized voxel-based morphometry (VBM) protocol on high-resolution 3D magnetic resonance images. The following three experiments were carried out: 1) contrast between the 14 volunteers with TAS-20 scores > or = 61 (alexithymic) and the 30 with scores < 51 (non-alexithymic), 2) correlation of TAS-20 scores on the whole sample and 3) contrast between the 14 alexithymic and 14 non-alexithymic matched by age. The significant threshold for VBM comparisons and correlation was set at p<0.005 uncorrected.The alexithymic group showed smaller GM volume in the anterior cingulate cortex (cluster size: 735 voxel no.; z=3.26; stereotaxic coordinates: -12, 22, 30) and middle temporal gyrus (256; 3.21; -60, 2, -20). Of specific biological relevance, smaller clusters were located in the anterior insula, orbitofrontal cortex and superior temporal sulcus. The opposite comparison was negative. The correlation analysis confirmed the pattern of results mainly in the left hemisphere.RESULTSThe alexithymic group showed smaller GM volume in the anterior cingulate cortex (cluster size: 735 voxel no.; z=3.26; stereotaxic coordinates: -12, 22, 30) and middle temporal gyrus (256; 3.21; -60, 2, -20). Of specific biological relevance, smaller clusters were located in the anterior insula, orbitofrontal cortex and superior temporal sulcus. The opposite comparison was negative. The correlation analysis confirmed the pattern of results mainly in the left hemisphere.Our findings suggest that the ability to process emotional aspects of the self correlates with morphology of a specific set of cerebral structures known to be involved in decision making and self awareness and rich in neurons subserving social competence.CONCLUSIONSOur findings suggest that the ability to process emotional aspects of the self correlates with morphology of a specific set of cerebral structures known to be involved in decision making and self awareness and rich in neurons subserving social competence. AbstractBackgroundAlexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults. MethodsFifty-four female volunteers were enrolled in the study and the 20-item Toronto Alexithymia Scale (TAS-20) was self-administered. Gray matter (GM) volume was assessed with an optimized voxel-based morphometry (VBM) protocol on high-resolution 3D magnetic resonance images. The following three experiments were carried out: 1) contrast between the 14 volunteers with TAS-20 scores ≥ 61 (alexithymic) and the 30 with scores < 51 (non-alexithymic), 2) correlation of TAS-20 scores on the whole sample and 3) contrast between the 14 alexithymic and 14 non-alexithymic matched by age. The significant threshold for VBM comparisons and correlation was set at p< 0.005 uncorrected. ResultsThe alexithymic group showed smaller GM volume in the anterior cingulate cortex (cluster size: 735 voxel no.; z= 3.26; stereotaxic coordinates: − 12, 22, 30) and middle temporal gyrus (256; 3.21; − 60, 2, − 20). Of specific biological relevance, smaller clusters were located in the anterior insula, orbitofrontal cortex and superior temporal sulcus. The opposite comparison was negative. The correlation analysis confirmed the pattern of results mainly in the left hemisphere. ConclusionsOur findings suggest that the ability to process emotional aspects of the self correlates with morphology of a specific set of cerebral structures known to be involved in decision making and self awareness and rich in neurons subserving social competence. Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults. Methods - Fifty-four female volunteers were enrolled in the study and the 20- item Toronto Alexithymia Scale (TAS-20) was self-administered. Gray matter (GM) volume was assessed with an optimized voxel-based morphometry (VBM) protocol on high-resolution 3D magnetic resonance images. The following three experiments were carried out: 1) contrast between the 14 volunteers with TAS- 20 scores >= 61 (alexithymic) and the 30 with scores < 51 (non-alexithymic), 2) correlation of TAS-20 scores on the whole sample and 3) contrast between the 14 alexithymic and 14 non-alexithymic matched by age. The significant threshold for VBM comparisons and correlation was set at p < 0.005 uncorrected. Results - The alexithymic group showed smaller GM volume in the anterior cingulate cortex (cluster size: 735 voxel no.; z = 3.26; stereotaxic coordinates: - 12, 22, 30) and middle temporal gyrus (256; 3.21; - 60, 2, - 20). Of specific biological relevance, smaller clusters were located in the anterior insula, orbitofrontal cortex and superior temporal sulcus. The opposite comparison was negative. The correlation analysis confirmed the pattern of results mainly in the left hemisphere. Conclusions - Our findings suggest that the ability to process emotional aspects of the self correlates with morphology of a specific set of cerebral structures known to be involved in decision making and self awareness and rich in neurons subserving social competence. [Copyright Elsevier B.V.] Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study was to investigate whether alexithymia is associated with a specific cerebral morphology of candidate structures in healthy adults. Fifty-four female volunteers were enrolled in the study and the 20-item Toronto Alexithymia Scale (TAS-20) was self-administered. Gray matter (GM) volume was assessed with an optimized voxel-based morphometry (VBM) protocol on high-resolution 3D magnetic resonance images. The following three experiments were carried out: 1) contrast between the 14 volunteers with TAS-20 scores > or = 61 (alexithymic) and the 30 with scores < 51 (non-alexithymic), 2) correlation of TAS-20 scores on the whole sample and 3) contrast between the 14 alexithymic and 14 non-alexithymic matched by age. The significant threshold for VBM comparisons and correlation was set at p<0.005 uncorrected. The alexithymic group showed smaller GM volume in the anterior cingulate cortex (cluster size: 735 voxel no.; z=3.26; stereotaxic coordinates: -12, 22, 30) and middle temporal gyrus (256; 3.21; -60, 2, -20). Of specific biological relevance, smaller clusters were located in the anterior insula, orbitofrontal cortex and superior temporal sulcus. The opposite comparison was negative. The correlation analysis confirmed the pattern of results mainly in the left hemisphere. Our findings suggest that the ability to process emotional aspects of the self correlates with morphology of a specific set of cerebral structures known to be involved in decision making and self awareness and rich in neurons subserving social competence. |
| Author | Perez, Jorge Boccardi, Marina Bonetti, Matteo Rossi, Giuseppe Frisoni, Giovanni B. Borsci, Genoveffa Rossi, Roberta |
| Author_xml | – sequence: 1 givenname: Genoveffa surname: Borsci fullname: Borsci, Genoveffa organization: LENITEM (Laboratory of Epidemiology, Neuroimaging and Telemedicine) — IRCCS S. Giovanni di Dio — FBF, Brescia, Italy – sequence: 2 givenname: Marina surname: Boccardi fullname: Boccardi, Marina organization: LENITEM (Laboratory of Epidemiology, Neuroimaging and Telemedicine) — IRCCS S. Giovanni di Dio — FBF, Brescia, Italy – sequence: 3 givenname: Roberta surname: Rossi fullname: Rossi, Roberta organization: Psychosocial Rehabilitation Unit — IRCCS S. Giovanni di Dio — FBF, Brescia, Italy – sequence: 4 givenname: Giuseppe surname: Rossi fullname: Rossi, Giuseppe organization: Psychosocial Rehabilitation Unit — IRCCS S. Giovanni di Dio — FBF, Brescia, Italy – sequence: 5 givenname: Jorge surname: Perez fullname: Perez, Jorge organization: Biological Psychiatry Unit — IRCCS S. Giovanni di Dio — FBF, Brescia, Italy – sequence: 6 givenname: Matteo surname: Bonetti fullname: Bonetti, Matteo organization: Service of Neuroradiology, Istituto Clinico Città di Brescia, Brescia, Italy – sequence: 7 givenname: Giovanni B. surname: Frisoni fullname: Frisoni, Giovanni B. email: gfrisoni@fatebenefratelli.it organization: LENITEM (Laboratory of Epidemiology, Neuroimaging and Telemedicine) — IRCCS S. Giovanni di Dio — FBF, Brescia, Italy |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21243862$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/18718670$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkl2L1DAYhYOsuLOrP8Ab6Y3etearSauwMCx-wYIX6nVIk7dOapuMSUftvzdlRoUFd69CwnNOeM95L9CZDx4QekpwRTARL4dq0LaiGDcVlhUm7AHakFqyktZEnqFNZuoSMyrP0UVKA8ZYtBI_QuekkaQREm-Q2I7wy827ZXK6cL7YgR7zrfgZJvCvim3RRZ2fpxD3uzCGr0uR5oNdHqOHvR4TPDmdl-jL2zefr9-XNx_ffbje3pSmbthcEsMaSxveGGgtFTWz0uieM9nX1DDgpBaklVJyCz0xuuGWcF4T6LqOcWo7doleHH33MXw_QJrV5JKBcdQewiEpIVoqMRP3grWkUtQEZ_DZCTx0E1i1j27ScVF_IsnA8xOgk9FjH7U3Lv3lKKGcNYJmjhw5E0NKEfp_Vlit9ahB5XrUWo_CUuV6skbe0hg369kFP-eYxzuVr49KyGn_cBBVMg68AesimFnZ4O5UX91Sm9F5l8f7BgukIRyizzUqohJVWH1aF2fdG9xgTFu-Dtv-3-Cez38Dfx3PCQ |
| CODEN | JADID7 |
| CitedBy_id | crossref_primary_10_1016_j_neuropsychologia_2013_12_006 crossref_primary_10_1097_PSY_0000000000000605 crossref_primary_10_1016_j_neulet_2022_136445 crossref_primary_10_1007_s00426_021_01538_x crossref_primary_10_1016_j_schres_2012_08_026 crossref_primary_10_1111_pcn_12318 crossref_primary_10_1007_s13760_020_01581_2 crossref_primary_10_1016_j_brainres_2012_10_044 crossref_primary_10_1016_j_neuropsychologia_2009_12_033 crossref_primary_10_1016_S1607_551X_10_70048_6 crossref_primary_10_1007_s00429_014_0790_0 crossref_primary_10_1111_acps_12234 crossref_primary_10_1016_j_jad_2011_06_012 crossref_primary_10_1176_appi_neuropsych_13070170 crossref_primary_10_1016_j_comppsych_2014_09_006 crossref_primary_10_1080_23279095_2020_1786693 crossref_primary_10_3233_JAD_180378 crossref_primary_10_3109_02770903_2010_535883 crossref_primary_10_3389_fnana_2022_1028546 crossref_primary_10_1016_j_neubiorev_2018_01_004 crossref_primary_10_1002_hbm_22879 crossref_primary_10_1016_j_dcn_2016_12_006 crossref_primary_10_1080_15294145_2015_1089184 crossref_primary_10_1002_hbm_25588 crossref_primary_10_1016_j_jad_2017_06_054 crossref_primary_10_1016_j_concog_2010_06_024 crossref_primary_10_1093_cercor_bhac184 crossref_primary_10_1002_hbm_22595 crossref_primary_10_1016_j_neuropsychologia_2016_01_021 crossref_primary_10_1093_ijnp_pyv129 crossref_primary_10_1016_j_neubiorev_2015_04_008 crossref_primary_10_1016_j_paid_2010_05_001 crossref_primary_10_1093_scan_nss048 crossref_primary_10_1016_j_jpsychores_2009_04_011 crossref_primary_10_1111_sjop_12287 crossref_primary_10_1016_j_jad_2015_12_057 crossref_primary_10_1093_scan_nsv110 crossref_primary_10_1016_j_neuroimage_2015_08_014 crossref_primary_10_1016_j_parkreldis_2016_03_021 crossref_primary_10_1093_scan_nst058 crossref_primary_10_1016_j_neuroscience_2018_06_045 crossref_primary_10_1007_s12310_023_09568_z crossref_primary_10_3389_fpsyg_2014_00774 crossref_primary_10_3758_s13415_016_0445_0 crossref_primary_10_1016_j_cortex_2014_02_017 crossref_primary_10_1038_mp_2012_51 crossref_primary_10_1111_j_1467_6494_2011_00717_x crossref_primary_10_1186_s13034_020_00338_2 crossref_primary_10_1055_a_1882_6544 crossref_primary_10_3389_fpsyg_2015_00589 crossref_primary_10_1080_10400419_2017_1263507 crossref_primary_10_1016_j_pscychresns_2013_03_007 crossref_primary_10_1186_s12888_024_05615_4 crossref_primary_10_1007_s00213_013_3018_8 crossref_primary_10_1111_j_1365_2869_2010_00865_x crossref_primary_10_1016_j_neubiorev_2021_07_036 crossref_primary_10_1016_j_neures_2011_01_019 crossref_primary_10_1002_hbm_21085 crossref_primary_10_1016_j_jad_2022_07_039 crossref_primary_10_1007_s40750_018_0102_7 crossref_primary_10_1002_hbm_21122 crossref_primary_10_1016_j_ridd_2022_104378 crossref_primary_10_1016_j_neuropsychologia_2017_07_034 crossref_primary_10_1016_j_ando_2014_06_001 crossref_primary_10_3389_fpsyg_2015_01149 crossref_primary_10_1016_j_bbi_2013_10_024 crossref_primary_10_1093_scan_nsq084 crossref_primary_10_1016_j_neuropsychologia_2019_107228 crossref_primary_10_1080_13554794_2010_532503 crossref_primary_10_1371_journal_pone_0139807 crossref_primary_10_1590_1980_57642018dn13_010003 |
| Cites_doi | 10.1006/nimg.2002.1087 10.1006/nimg.2002.1202 10.1007/BF03324618 10.1002/jclp.20324 10.1016/S0304-3940(03)00070-3 10.1111/j.1749-6632.2001.tb03476.x 10.1016/j.neuroimage.2006.04.186 10.1016/j.tics.2004.01.004 10.1162/089892998562924 10.1192/bjp.bp.106.034728 10.1159/000087846 10.1038/scientificamerican1106-54 10.1006/nimg.1997.0299 10.1016/S0165-1781(00)00189-X 10.1016/j.tics.2005.06.008 10.1016/0010-440X(94)90197-X 10.1016/j.neuroimage.2005.12.002 10.1016/S0022-3999(96)00221-8 10.1038/nn1107-1345 10.1016/j.tics.2007.01.001 10.1016/0022-3999(94)90005-1 10.1093/brain/awg131 10.1159/000288664 10.1007/BF00227301 10.1016/j.neuroscience.2006.04.084 10.1016/S0022-3999(99)00083-5 10.1146/annurev.neuro.27.070203.144230 10.1016/j.tics.2005.06.005 10.1016/S1364-6613(00)01483-2 10.1196/annals.1364.029 10.1053/comp.2002.35905 10.1016/S0022-3999(96)00224-3 10.2190/P474-62H5-2250-W343 10.1016/0022-3999(94)90006-X 10.1159/000082028 10.1016/j.neuroimage.2004.06.030 10.1016/S0022-3999(98)00053-1 10.1016/S0959-4388(02)00301-X 10.1097/01.PSY.0000097348.45087.96 10.1159/000085148 10.1016/S0022-3999(96)00228-0 10.1093/brain/118.1.279 10.1073/pnas.96.9.5268 10.1176/ajp.150.7.1105 10.1093/brain/awl004 10.1016/S0006-3223(03)00168-9 10.1176/appi.ajp.159.6.961 10.1159/000286529 10.1053/comp.2001.27892 10.1007/BF00227183 10.1016/S0033-3182(91)72086-0 10.1016/S1474-4422(03)00304-1 |
| ContentType | Journal Article |
| Copyright | 2008 Elsevier B.V. Elsevier B.V. 2009 INIST-CNRS |
| Copyright_xml | – notice: 2008 Elsevier B.V. – notice: Elsevier B.V. – notice: 2009 INIST-CNRS |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7QJ 7X8 |
| DOI | 10.1016/j.jad.2008.07.013 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Applied Social Sciences Index & Abstracts (ASSIA) MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Applied Social Sciences Index and Abstracts (ASSIA) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic Applied Social Sciences Index and Abstracts (ASSIA) MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 1573-2517 |
| EndPage | 215 |
| ExternalDocumentID | 18718670 21243862 10_1016_j_jad_2008_07_013 S0165032708002942 1_s2_0_S0165032708002942 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Comparative Study |
| GroupedDBID | --- --K --M .1- .FO .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 29J 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM AABNK AAEDT AAEDW AAGKA AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATTM AAWTL AAXKI AAXUO AAYWO ABBQC ABFNM ABIVO ABJNI ABLJU ABMAC ABMZM ABWVN ABXDB ACDAQ ACGFS ACHQT ACIEU ACIUM ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADMUD ADNMO ADVLN AEBSH AEIPS AEKER AENEX AEUPX AEVXI AFJKZ AFPUW AFRHN AFTJW AFXIZ AGCQF AGHFR AGQPQ AGUBO AGYEJ AHHHB AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CS3 DU5 EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HEG HMK HMO HMQ HMW HVGLF HZ~ IHE J1W KOM M29 M2V M39 M3V M41 MO0 N9A O-L O9- OAUVE OH0 OU- OZT P-8 P-9 P2P PC. Q38 R2- ROL RPZ SAE SCC SDF SDG SDP SEL SES SEW SNS SPCBC SPS SSH SSZ T5K UV1 WUQ Z5R ZGI ~G- 0SF AACTN AFCTW AFKWA AJOXV AMFUW NCXOZ RIG AAIAV ABLVK ABYKQ AJBFU EFLBG LCYCR ZA5 AAYXX AGRNS CITATION IQODW CGR CUY CVF ECM EIF NPM 7QJ 7X8 |
| ID | FETCH-LOGICAL-c583t-1c38d2848ce9d2653d7caf437f52c3e4156197774def1ca84d14451ebbb342db3 |
| IEDL.DBID | AIKHN |
| ISSN | 0165-0327 1573-2517 |
| IngestDate | Fri Jul 11 11:15:00 EDT 2025 Thu Jul 10 20:09:05 EDT 2025 Mon Jul 21 06:06:52 EDT 2025 Thu Apr 10 08:59:49 EDT 2025 Thu Apr 24 23:11:39 EDT 2025 Tue Jul 01 02:03:45 EDT 2025 Fri Feb 23 02:31:45 EST 2024 Sun Feb 23 10:18:53 EST 2025 Tue Aug 26 17:09:15 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Neuroimaging Healthy subjects TAS-20 MRI Alexithymia Voxel-based morphometry Human Healthy subject Central nervous system Personality Nuclear magnetic resonance imaging Encephalon Morphology Medical imagery Morphometry |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 CC BY 4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c583t-1c38d2848ce9d2653d7caf437f52c3e4156197774def1ca84d14451ebbb342db3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 |
| PMID | 18718670 |
| PQID | 57276510 |
| PQPubID | 24071 |
| PageCount | 8 |
| ParticipantIDs | proquest_miscellaneous_66927036 proquest_miscellaneous_57276510 pubmed_primary_18718670 pascalfrancis_primary_21243862 crossref_primary_10_1016_j_jad_2008_07_013 crossref_citationtrail_10_1016_j_jad_2008_07_013 elsevier_sciencedirect_doi_10_1016_j_jad_2008_07_013 elsevier_clinicalkeyesjournals_1_s2_0_S0165032708002942 elsevier_clinicalkey_doi_10_1016_j_jad_2008_07_013 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2009-04-01 |
| PublicationDateYYYYMMDD | 2009-04-01 |
| PublicationDate_xml | – month: 04 year: 2009 text: 2009-04-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | Oxford |
| PublicationPlace_xml | – name: Oxford – name: Netherlands |
| PublicationTitle | Journal of affective disorders |
| PublicationTitleAlternate | J Affect Disord |
| PublicationYear | 2009 |
| Publisher | Elsevier B.V Elsevier |
| Publisher_xml | – name: Elsevier B.V – name: Elsevier |
| References | Karlsson, Näätänen, Stenman (bib28) 2008; 192 Adolphs (bib1) 2002; 12 Allman, Hakeem, Erwin, Nimchinsky, Hof (bib3) 2001; 935 Northoff, Heinzel, de Greck, Bermpohl, Dobrowolny, Panksepp (bib39) 2006; 31 Devinsky, Morrell, Vogt (bib16) 1995; 118 Watson, Jones, Allman (bib61) 2006; 141 Good, Scahill, Fox, Ashburner, Friston, Chan, Crum, Rossor, Frackowiak (bib21) 2002; 17 Loas, Otmani, Lecercle, Jouvent (bib31) 2000; 96 Aftanas, Varlamov, Reva, Pavlov (bib2) 2003; 340 Vanheule, Vandenbergen, Desmet, Rosseel, Insleghers (bib59) 2007; 37 Parker, Taylor, Bagby, Acklin (bib41) 1993; 150 Vanheule, Desmet, Meganck, Bogaerts (bib58) 2007; 63 Guttman, Laporte (bib24) 2002; 43 Spitzer, Siebel-Jurges, Barnow, Grabe, Freyberger (bib53) 2005; 74 Von Economo, Koskinas (bib60) 1925 Rizzolatti, Fadiga, Matelli, Bettinardi, Paulesu, Perani, Fazio (bib48) 1996; 111 Sifneos (bib52) 1973; 22 Phan, Wager, Taylor, Liberzon (bib43) 2002; 16 Salminen, Saarijarvi, Aarela, Toikka, Kauhanen (bib50) 1999; 46 Allman, Watson, Tetreault, Hakeem (bib4) 2005; 8 Riello, Sabattoli, Beltramello, Bonetti, Bono, Falini, Magnani, Minonzio, Piovan, Alaimo, Ettori, Galluzzi, Locatelli, Noiszewska, Testa, Frisoni (bib46) 2005; 17 Parker, Taylor, Bagby (bib42) 1993; 59 Northoff, Bermpohl (bib38) 2004; 8 Caretti, La Barbera (bib13) 2005 Uddin, Iacoboni, Lange, Keenan (bib57) 2007; 11 Bressi, Taylor, Parker, Bressi, Brambilla, Aguglia, Allegranti, Bongiorno, Giberti, Bucca, Todarello, Callegari, Vender, Gala, Invernizzi (bib11) 1996; 41 Taylor, Bagby, Parker (bib54) 1991; 32 Berthoz, Artiges, Van de Moortele, Poline, Rouquette, Consoli, Martinot (bib10) 2002; 159 Ashburner, Csernansky, Davatzikos, Fox, Frisoni, Thompson (bib6) 2003; 2 Ochsner, Ray, Cooper, Robertson, Chopra, Gabrieli, Gross (bib40) 2004; 23 Phillips, Drevets, Rauch, Lane (bib44) 2003; 54 Kokkonen, Karvonen, Veijola, Läksy, Jokelainen, Järvelin, Joukamaa (bib29) 2001; 42 Grafton, Arbib, Fadiga, Rizzolatti (bib22) 1996; 112 Lane, Reiman, Axelrod, Yun, Holmes, Schwartz (bib30) 1998; 10 Kano, Fukudo, Gyoba, Kamachi, Tagawa, Mochizuki, Itoh, Hongo, Yanai (bib27) 2003; 126 Bach, de Zwaan, Ackard, Nutzinger, Mitchell (bib7) 1994; 35 Rizzolatti, Fogassi, Gallese (bib49) 2006; 295 Nimchinsky, Gilissen, Allman, Perl, Erwin, Hof (bib36) 1999; 96 Northoff (bib37) 2005; 9 Taylor, Parker, Bagby, Bourke (bib55) 1996; 41 Rizzolatti, Craighero (bib47) 2004; 27 Schacter, Addis (bib51) 2007; 10 Moriguchi, Ohnishi, Lane, Maeda, Mori, Nemoto, Matsuda, Komaki (bib33) 2006; 32 Bagby, Taylor, Parker (bib9) 1994; 38 Nemiah, Freyberger, Sifneos (bib34) 1976; vol 3 Bagby, Parker, Taylor (bib8) 1994; 38 Damasio (bib15) 1999 Evans, Kamber, Collins, Macdonald (bib17) 1994 Ashburner, Neelin, Collins, Evans, Friston (bib5) 1997; 6 Ham, Lee, Lee, Kim, Choi, Oh, Jung, Lyoo, Choi (bib25) 2005; 52 Honkalampi, Hintikka, Tanskanen, Lehtonen, Viinamäki (bib26) 2000; 48 Cavanna, Trimble (bib14) 2006; 129 Taylor, Bagby, Parker (bib56) 1997 Frewen, Pain, Dozois, Lanius (bib18) 2006; 1071 Gündel, López-Sala, Ceballos-Baumann, Deus, Cardoner, Marten-Mittag, Soriano-Mas, Pujol (bib23) 2004; 66 Porcelli, Leoci, Guerra, Taylor, Bagby (bib45) 1996; 41 Bush, Luu, Posner (bib12) 2000; 4 Marchesi, Fontò, Balista, Cimmino, Maggini (bib32) 2005; 74 Frewen (10.1016/j.jad.2008.07.013_bib18) 2006; 1071 Good (10.1016/j.jad.2008.07.013_bib21) 2002; 17 Kokkonen (10.1016/j.jad.2008.07.013_bib29) 2001; 42 Ashburner (10.1016/j.jad.2008.07.013_bib5) 1997; 6 Karlsson (10.1016/j.jad.2008.07.013_bib28) 2008; 192 Cavanna (10.1016/j.jad.2008.07.013_bib14) 2006; 129 Damasio (10.1016/j.jad.2008.07.013_bib15) 1999 Northoff (10.1016/j.jad.2008.07.013_bib39) 2006; 31 Taylor (10.1016/j.jad.2008.07.013_bib56) 1997 Vanheule (10.1016/j.jad.2008.07.013_bib58) 2007; 63 Nemiah (10.1016/j.jad.2008.07.013_bib34) 1976; vol 3 Moriguchi (10.1016/j.jad.2008.07.013_bib33) 2006; 32 Ham (10.1016/j.jad.2008.07.013_bib25) 2005; 52 Marchesi (10.1016/j.jad.2008.07.013_bib32) 2005; 74 Porcelli (10.1016/j.jad.2008.07.013_bib45) 1996; 41 Watson (10.1016/j.jad.2008.07.013_bib61) 2006; 141 Devinsky (10.1016/j.jad.2008.07.013_bib16) 1995; 118 Evans (10.1016/j.jad.2008.07.013_bib17) 1994 Taylor (10.1016/j.jad.2008.07.013_bib55) 1996; 41 Caretti (10.1016/j.jad.2008.07.013_bib13) 2005 Bach (10.1016/j.jad.2008.07.013_bib7) 1994; 35 Allman (10.1016/j.jad.2008.07.013_bib4) 2005; 8 Salminen (10.1016/j.jad.2008.07.013_bib50) 1999; 46 Nimchinsky (10.1016/j.jad.2008.07.013_bib36) 1999; 96 Allman (10.1016/j.jad.2008.07.013_bib3) 2001; 935 Northoff (10.1016/j.jad.2008.07.013_bib38) 2004; 8 Loas (10.1016/j.jad.2008.07.013_bib31) 2000; 96 Bressi (10.1016/j.jad.2008.07.013_bib11) 1996; 41 Northoff (10.1016/j.jad.2008.07.013_bib37) 2005; 9 Aftanas (10.1016/j.jad.2008.07.013_bib2) 2003; 340 Bush (10.1016/j.jad.2008.07.013_bib12) 2000; 4 Riello (10.1016/j.jad.2008.07.013_bib46) 2005; 17 Adolphs (10.1016/j.jad.2008.07.013_bib1) 2002; 12 Parker (10.1016/j.jad.2008.07.013_bib41) 1993; 150 Rizzolatti (10.1016/j.jad.2008.07.013_bib47) 2004; 27 Bagby (10.1016/j.jad.2008.07.013_bib9) 1994; 38 Grafton (10.1016/j.jad.2008.07.013_bib22) 1996; 112 Phan (10.1016/j.jad.2008.07.013_bib43) 2002; 16 Ochsner (10.1016/j.jad.2008.07.013_bib40) 2004; 23 Gündel (10.1016/j.jad.2008.07.013_bib23) 2004; 66 Schacter (10.1016/j.jad.2008.07.013_bib51) 2007; 10 Taylor (10.1016/j.jad.2008.07.013_bib54) 1991; 32 Uddin (10.1016/j.jad.2008.07.013_bib57) 2007; 11 Berthoz (10.1016/j.jad.2008.07.013_bib10) 2002; 159 Rizzolatti (10.1016/j.jad.2008.07.013_bib49) 2006; 295 Bagby (10.1016/j.jad.2008.07.013_bib8) 1994; 38 Guttman (10.1016/j.jad.2008.07.013_bib24) 2002; 43 Spitzer (10.1016/j.jad.2008.07.013_bib53) 2005; 74 Phillips (10.1016/j.jad.2008.07.013_bib44) 2003; 54 Vanheule (10.1016/j.jad.2008.07.013_bib59) 2007; 37 Parker (10.1016/j.jad.2008.07.013_bib42) 1993; 59 Sifneos (10.1016/j.jad.2008.07.013_bib52) 1973; 22 Honkalampi (10.1016/j.jad.2008.07.013_bib26) 2000; 48 Rizzolatti (10.1016/j.jad.2008.07.013_bib48) 1996; 111 Kano (10.1016/j.jad.2008.07.013_bib27) 2003; 126 Ashburner (10.1016/j.jad.2008.07.013_bib6) 2003; 2 Lane (10.1016/j.jad.2008.07.013_bib30) 1998; 10 Von Economo (10.1016/j.jad.2008.07.013_bib60) 1925 |
| References_xml | – volume: 41 start-page: 561 year: 1996 end-page: 568 ident: bib55 article-title: Relationships between alexithymia and psychological characteristics associated with eating disorders publication-title: J. Psychosom. Res. – volume: 32 start-page: 1472 year: 2006 end-page: 1482 ident: bib33 article-title: Impaired self awareness and theory of mind: an fMRI study of mentalizing in alexithymia publication-title: Neuroimage – volume: 43 start-page: 448 year: 2002 end-page: 455 ident: bib24 article-title: Alexithymia, empathy, and psychological symptoms in a family context publication-title: Compr. Psychiatry – volume: 38 start-page: 33 year: 1994 end-page: 40 ident: bib9 article-title: The twenty-item Toronto Alexithymia Scale-II. Convergent, discriminant, and concurrent validity publication-title: J. Psychosom. Res. – volume: 74 start-page: 240 year: 2005 end-page: 246 ident: bib53 article-title: Alexithymia and interpersonal problems publication-title: Psychother. Psychosom. – volume: 112 start-page: 103 year: 1996 end-page: 111 ident: bib22 article-title: Localization of grasp representations in humans by positron emission tomography. 2. Observation compared with imagination publication-title: Exp. Brain Res – volume: vol 3 start-page: 430 year: 1976 end-page: 439 ident: bib34 article-title: Alexithymia: a view of the psychosomatic process publication-title: Modern Trends in Psychosomatic Medicine – volume: 118 start-page: 279 year: 1995 end-page: 306 ident: bib16 article-title: Contributions of anterior cingulate cortex to behaviour publication-title: Brain – volume: 141 start-page: 1107 year: 2006 end-page: 1112 ident: bib61 article-title: Dendritic architecture of the von Economo neurons publication-title: Neuroscience – year: 1997 ident: bib56 article-title: Disorders of Affect Regulation. Alexithymia in Medical and Psychiatric Illness – volume: 32 start-page: 153 year: 1991 end-page: 164 ident: bib54 article-title: The alexithymia construct. A potential paradigm for psychosomatic medicine publication-title: Psychosomatics – volume: 96 start-page: 63 year: 2000 end-page: 74 ident: bib31 article-title: Relationships between the emotional and cognitive components of alexithymia and dependency in alcoholics publication-title: Psychiatry Res. – volume: 38 start-page: 23 year: 1994 end-page: 32 ident: bib8 article-title: The twenty-item Toronto Alexithymia Scale-I. Item selection and cross-validation of the factor structure publication-title: J. Psychosom. Res. – volume: 96 start-page: 5268 year: 1999 end-page: 5273 ident: bib36 article-title: A neuronal morphologic type unique to humans and great apes publication-title: Proc. Natl. Acad. Sci. – volume: 74 start-page: 56 year: 2005 end-page: 60 ident: bib32 article-title: Relationship between alexithymia and panic disorder: a longitudinal study to answer an open question publication-title: Psychother. Psychosom. – volume: 159 start-page: 961 year: 2002 end-page: 967 ident: bib10 article-title: Effect of impaired recognition and expression of emotions on frontocingulate cortices: an fMRI study of men with alexithymia publication-title: Am. J. Psychiatry – volume: 9 start-page: 408 year: 2005 end-page: 409 ident: bib37 article-title: Is emotion regulation self-regulation? publication-title: Trends Cogn. Sci. – volume: 31 start-page: 440 year: 2006 end-page: 457 ident: bib39 article-title: Self-referential processing in our brain — a meta-analysis of imaging studies on the self publication-title: Neuroimage – volume: 6 start-page: 344 year: 1997 end-page: 352 ident: bib5 article-title: Incorporating prior knowledge into image registration publication-title: Neuroimage – volume: 935 start-page: 107 year: 2001 end-page: 117 ident: bib3 article-title: The anterior cingulate cortex. The evolution of an interface between emotion and cognition publication-title: Ann. N. Y. Acad. Sci – volume: 63 start-page: 109 year: 2007 end-page: 117 ident: bib58 article-title: Alexithymia and interpersonal problems publication-title: J. Clin. Psychol. – year: 1925 ident: bib60 article-title: Die Cytoarchitektonik der Hirnrinde des Erwachsenen Menschen – volume: 12 start-page: 169 year: 2002 end-page: 177 ident: bib1 article-title: Neural systems for recognizing emotion publication-title: Curr. Opin. Neurobiol. – volume: 150 start-page: 1105 year: 1993 end-page: 1107 ident: bib41 article-title: Alexithymia in panic disorder and simple phobia: a comparative study publication-title: Am. J. Psychiatry – volume: 4 start-page: 215 year: 2000 end-page: 222 ident: bib12 article-title: Cognitive and emotional influences in anterior cingulate cortex publication-title: Trends Cogn. Sci. – volume: 8 start-page: 102 year: 2004 end-page: 107 ident: bib38 article-title: Cortical midline structures and the self publication-title: Trends Cogn. Sci. – volume: 10 start-page: 525 year: 1998 end-page: 535 ident: bib30 article-title: Neural correlates of levels of emotional awareness. Evidence of an interaction between emotion and attention in the anterior cingulate cortex publication-title: J. Cogn. Neurosci. – volume: 23 start-page: 483 year: 2004 end-page: 499 ident: bib40 article-title: For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion publication-title: Neuroimage – volume: 27 start-page: 169 year: 2004 end-page: 192 ident: bib47 article-title: The mirror-neuron system publication-title: Annu. Rev. Neurosci. – volume: 10 start-page: 1345 year: 2007 end-page: 1347 ident: bib51 article-title: The optimistic brain publication-title: Nat. Neurosci. – year: 1999 ident: bib15 article-title: The Feeling of What Happens: Body and Emotion in the Making of Consciousness – volume: 54 start-page: 504 year: 2003 end-page: 514 ident: bib44 article-title: Neurobiology of emotion perception I: the neural basis of normal emotion perception publication-title: Biol. Psychiatry – volume: 295 start-page: 54 year: 2006 end-page: 61 ident: bib49 article-title: Mirrors of the mind publication-title: Sci. Am. – volume: 340 start-page: 57 year: 2003 end-page: 60 ident: bib2 article-title: Disruption of early event-related theta synchronization of human EEG in alexithymics viewing affective pictures publication-title: Neurosci. Lett. – volume: 192 start-page: 32 year: 2008 end-page: 38 ident: bib28 article-title: Cortical activation in alexithymia as a response to emotional stimuli publication-title: Brit. J. Psychiat. – volume: 8 start-page: 367 year: 2005 end-page: 373 ident: bib4 article-title: Intuition and autism: a possible role for Von Economo neurons publication-title: Trends Cogn. Sci – volume: 126 start-page: 1474 year: 2003 end-page: 1484 ident: bib27 article-title: Specific brain processing of facial expressions in people with alexithymia: an H(2)(15)-O-PET study publication-title: Brain – volume: 41 start-page: 569 year: 1996 end-page: 573 ident: bib45 article-title: A longitudinal study of alexithymia and psychological distress in inflammatory bowel disease publication-title: J. Psychosom. Res. – volume: 17 start-page: 29 year: 2002 end-page: 46 ident: bib21 article-title: Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias publication-title: Neuroimage – volume: 66 start-page: 132 year: 2004 end-page: 140 ident: bib23 article-title: Alexithymia correlates with the size of the right anterior cingulate publication-title: Psychosom. Med. – volume: 22 start-page: 255 year: 1973 end-page: 262 ident: bib52 article-title: The prevalence of alexithymic characteristics in psychosomatic patients publication-title: Psychother. Psychosom. – volume: 111 start-page: 246 year: 1996 end-page: 252 ident: bib48 article-title: Localization of grasp representations in humans by PET: 1. Observation versus execution publication-title: Exp. Brain Res. – volume: 37 start-page: 87 year: 2007 end-page: 98 ident: bib59 article-title: Alexithymia and core conflictual relationship themes: a study in a chronically fatigued primary care population publication-title: Int. J. Psychiatry Med. – volume: 1071 start-page: 397 year: 2006 end-page: 400 ident: bib18 article-title: Alexithymia in PTSD: psychometric and FMRI studies publication-title: Ann. N. Y. Acad. Sci. – volume: 42 start-page: 471 year: 2001 end-page: 476 ident: bib29 article-title: Prevalence and sociodemographic correlates of alexithymia in a population sample of young adults publication-title: Compr. Psychiatry – start-page: 263 year: 1994 end-page: 274 ident: bib17 article-title: An MRI-based probabilistic atlas of neuroanatomy publication-title: Magnetic Resonance Scanning and Epilepsy – volume: 59 start-page: 197 year: 1993 end-page: 202 ident: bib42 article-title: Alexithymia and the recognition of facial expressions of emotion publication-title: Psychother. Psychosom. – volume: 2 start-page: 79 year: 2003 end-page: 88 ident: bib6 article-title: Computer-assisted imaging to assess brain structure in healthy and diseased brains publication-title: Lancet Neurol. – volume: 16 start-page: 331 year: 2002 end-page: 348 ident: bib43 article-title: Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI publication-title: Neuroimage – volume: 52 start-page: 151 year: 2005 end-page: 154 ident: bib25 article-title: Association between the catechol publication-title: Neuropsychobiology – volume: 46 start-page: 75 year: 1999 end-page: 82 ident: bib50 article-title: Prevalence of alexithymia and its association with sociodemographic variables in the general population of Finland publication-title: J. Psychosom. Res. – year: 2005 ident: bib13 article-title: Alessitimia publication-title: Valutazione e trattamento – volume: 11 start-page: 153 year: 2007 end-page: 157 ident: bib57 article-title: The self and social cognition: the role of cortical midline structures and mirror neurons publication-title: Trends Cogn. Sci. – volume: 48 start-page: 99 year: 2000 end-page: 104 ident: bib26 article-title: Depression is strongly associated with alexithymia in the general population publication-title: J. Psychosom. Res. – volume: 129 start-page: 564 year: 2006 end-page: 583 ident: bib14 article-title: The precuneus: a review of its functional anatomy and behavioural correlates publication-title: Brain – volume: 35 start-page: 239 year: 1994 end-page: 243 ident: bib7 article-title: Alexithymia: relationship to personality disorders publication-title: Compr. Psychiatry – volume: 41 start-page: 551 year: 1996 end-page: 559 ident: bib11 article-title: Cross validation of the factor structure of the 20-item Toronto Alexithymia Scale: an Italian multicenter study publication-title: J. Psychosom. Res. – volume: 17 start-page: 329 year: 2005 end-page: 336 ident: bib46 article-title: Brain volumes in healthy adults aged 40 years and over: a voxel-based morphometry study publication-title: Aging Clin. Exp. Res – volume: 16 start-page: 331 year: 2002 ident: 10.1016/j.jad.2008.07.013_bib43 article-title: Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI publication-title: Neuroimage doi: 10.1006/nimg.2002.1087 – volume: 17 start-page: 29 year: 2002 ident: 10.1016/j.jad.2008.07.013_bib21 article-title: Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias publication-title: Neuroimage doi: 10.1006/nimg.2002.1202 – volume: 17 start-page: 329 year: 2005 ident: 10.1016/j.jad.2008.07.013_bib46 article-title: Brain volumes in healthy adults aged 40 years and over: a voxel-based morphometry study publication-title: Aging Clin. Exp. Res doi: 10.1007/BF03324618 – volume: 63 start-page: 109 year: 2007 ident: 10.1016/j.jad.2008.07.013_bib58 article-title: Alexithymia and interpersonal problems publication-title: J. Clin. Psychol. doi: 10.1002/jclp.20324 – volume: 340 start-page: 57 year: 2003 ident: 10.1016/j.jad.2008.07.013_bib2 article-title: Disruption of early event-related theta synchronization of human EEG in alexithymics viewing affective pictures publication-title: Neurosci. Lett. doi: 10.1016/S0304-3940(03)00070-3 – volume: 935 start-page: 107 year: 2001 ident: 10.1016/j.jad.2008.07.013_bib3 article-title: The anterior cingulate cortex. The evolution of an interface between emotion and cognition publication-title: Ann. N. Y. Acad. Sci doi: 10.1111/j.1749-6632.2001.tb03476.x – volume: 32 start-page: 1472 year: 2006 ident: 10.1016/j.jad.2008.07.013_bib33 article-title: Impaired self awareness and theory of mind: an fMRI study of mentalizing in alexithymia publication-title: Neuroimage doi: 10.1016/j.neuroimage.2006.04.186 – volume: 8 start-page: 102 year: 2004 ident: 10.1016/j.jad.2008.07.013_bib38 article-title: Cortical midline structures and the self publication-title: Trends Cogn. Sci. doi: 10.1016/j.tics.2004.01.004 – volume: 10 start-page: 525 year: 1998 ident: 10.1016/j.jad.2008.07.013_bib30 article-title: Neural correlates of levels of emotional awareness. Evidence of an interaction between emotion and attention in the anterior cingulate cortex publication-title: J. Cogn. Neurosci. doi: 10.1162/089892998562924 – volume: 192 start-page: 32 year: 2008 ident: 10.1016/j.jad.2008.07.013_bib28 article-title: Cortical activation in alexithymia as a response to emotional stimuli publication-title: Brit. J. Psychiat. doi: 10.1192/bjp.bp.106.034728 – volume: 52 start-page: 151 year: 2005 ident: 10.1016/j.jad.2008.07.013_bib25 article-title: Association between the catechol O-methyltransferase Val108/158Met polymorphism and alexithymia publication-title: Neuropsychobiology doi: 10.1159/000087846 – volume: 295 start-page: 54 year: 2006 ident: 10.1016/j.jad.2008.07.013_bib49 article-title: Mirrors of the mind publication-title: Sci. Am. doi: 10.1038/scientificamerican1106-54 – volume: 6 start-page: 344 year: 1997 ident: 10.1016/j.jad.2008.07.013_bib5 article-title: Incorporating prior knowledge into image registration publication-title: Neuroimage doi: 10.1006/nimg.1997.0299 – volume: 96 start-page: 63 year: 2000 ident: 10.1016/j.jad.2008.07.013_bib31 article-title: Relationships between the emotional and cognitive components of alexithymia and dependency in alcoholics publication-title: Psychiatry Res. doi: 10.1016/S0165-1781(00)00189-X – volume: 8 start-page: 367 year: 2005 ident: 10.1016/j.jad.2008.07.013_bib4 article-title: Intuition and autism: a possible role for Von Economo neurons publication-title: Trends Cogn. Sci doi: 10.1016/j.tics.2005.06.008 – year: 1925 ident: 10.1016/j.jad.2008.07.013_bib60 – volume: 35 start-page: 239 year: 1994 ident: 10.1016/j.jad.2008.07.013_bib7 article-title: Alexithymia: relationship to personality disorders publication-title: Compr. Psychiatry doi: 10.1016/0010-440X(94)90197-X – year: 1999 ident: 10.1016/j.jad.2008.07.013_bib15 – volume: 31 start-page: 440 year: 2006 ident: 10.1016/j.jad.2008.07.013_bib39 article-title: Self-referential processing in our brain — a meta-analysis of imaging studies on the self publication-title: Neuroimage doi: 10.1016/j.neuroimage.2005.12.002 – volume: 41 start-page: 569 year: 1996 ident: 10.1016/j.jad.2008.07.013_bib45 article-title: A longitudinal study of alexithymia and psychological distress in inflammatory bowel disease publication-title: J. Psychosom. Res. doi: 10.1016/S0022-3999(96)00221-8 – volume: 10 start-page: 1345 year: 2007 ident: 10.1016/j.jad.2008.07.013_bib51 article-title: The optimistic brain publication-title: Nat. Neurosci. doi: 10.1038/nn1107-1345 – volume: 11 start-page: 153 year: 2007 ident: 10.1016/j.jad.2008.07.013_bib57 article-title: The self and social cognition: the role of cortical midline structures and mirror neurons publication-title: Trends Cogn. Sci. doi: 10.1016/j.tics.2007.01.001 – volume: 38 start-page: 23 year: 1994 ident: 10.1016/j.jad.2008.07.013_bib8 article-title: The twenty-item Toronto Alexithymia Scale-I. Item selection and cross-validation of the factor structure publication-title: J. Psychosom. Res. doi: 10.1016/0022-3999(94)90005-1 – volume: 126 start-page: 1474 year: 2003 ident: 10.1016/j.jad.2008.07.013_bib27 article-title: Specific brain processing of facial expressions in people with alexithymia: an H(2)(15)-O-PET study publication-title: Brain doi: 10.1093/brain/awg131 – volume: 59 start-page: 197 year: 1993 ident: 10.1016/j.jad.2008.07.013_bib42 article-title: Alexithymia and the recognition of facial expressions of emotion publication-title: Psychother. Psychosom. doi: 10.1159/000288664 – volume: 111 start-page: 246 year: 1996 ident: 10.1016/j.jad.2008.07.013_bib48 article-title: Localization of grasp representations in humans by PET: 1. Observation versus execution publication-title: Exp. Brain Res. doi: 10.1007/BF00227301 – volume: 141 start-page: 1107 year: 2006 ident: 10.1016/j.jad.2008.07.013_bib61 article-title: Dendritic architecture of the von Economo neurons publication-title: Neuroscience doi: 10.1016/j.neuroscience.2006.04.084 – year: 2005 ident: 10.1016/j.jad.2008.07.013_bib13 article-title: Alessitimia – volume: 48 start-page: 99 year: 2000 ident: 10.1016/j.jad.2008.07.013_bib26 article-title: Depression is strongly associated with alexithymia in the general population publication-title: J. Psychosom. Res. doi: 10.1016/S0022-3999(99)00083-5 – volume: 27 start-page: 169 year: 2004 ident: 10.1016/j.jad.2008.07.013_bib47 article-title: The mirror-neuron system publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev.neuro.27.070203.144230 – volume: 9 start-page: 408 year: 2005 ident: 10.1016/j.jad.2008.07.013_bib37 article-title: Is emotion regulation self-regulation? publication-title: Trends Cogn. Sci. doi: 10.1016/j.tics.2005.06.005 – volume: 4 start-page: 215 year: 2000 ident: 10.1016/j.jad.2008.07.013_bib12 article-title: Cognitive and emotional influences in anterior cingulate cortex publication-title: Trends Cogn. Sci. doi: 10.1016/S1364-6613(00)01483-2 – volume: 1071 start-page: 397 year: 2006 ident: 10.1016/j.jad.2008.07.013_bib18 article-title: Alexithymia in PTSD: psychometric and FMRI studies publication-title: Ann. N. Y. Acad. Sci. doi: 10.1196/annals.1364.029 – volume: 43 start-page: 448 year: 2002 ident: 10.1016/j.jad.2008.07.013_bib24 article-title: Alexithymia, empathy, and psychological symptoms in a family context publication-title: Compr. Psychiatry doi: 10.1053/comp.2002.35905 – volume: 41 start-page: 561 year: 1996 ident: 10.1016/j.jad.2008.07.013_bib55 article-title: Relationships between alexithymia and psychological characteristics associated with eating disorders publication-title: J. Psychosom. Res. doi: 10.1016/S0022-3999(96)00224-3 – volume: 37 start-page: 87 year: 2007 ident: 10.1016/j.jad.2008.07.013_bib59 article-title: Alexithymia and core conflictual relationship themes: a study in a chronically fatigued primary care population publication-title: Int. J. Psychiatry Med. doi: 10.2190/P474-62H5-2250-W343 – volume: 38 start-page: 33 year: 1994 ident: 10.1016/j.jad.2008.07.013_bib9 article-title: The twenty-item Toronto Alexithymia Scale-II. Convergent, discriminant, and concurrent validity publication-title: J. Psychosom. Res. doi: 10.1016/0022-3999(94)90006-X – volume: 74 start-page: 56 year: 2005 ident: 10.1016/j.jad.2008.07.013_bib32 article-title: Relationship between alexithymia and panic disorder: a longitudinal study to answer an open question publication-title: Psychother. Psychosom. doi: 10.1159/000082028 – volume: 23 start-page: 483 year: 2004 ident: 10.1016/j.jad.2008.07.013_bib40 article-title: For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion publication-title: Neuroimage doi: 10.1016/j.neuroimage.2004.06.030 – volume: 46 start-page: 75 year: 1999 ident: 10.1016/j.jad.2008.07.013_bib50 article-title: Prevalence of alexithymia and its association with sociodemographic variables in the general population of Finland publication-title: J. Psychosom. Res. doi: 10.1016/S0022-3999(98)00053-1 – volume: vol 3 start-page: 430 year: 1976 ident: 10.1016/j.jad.2008.07.013_bib34 article-title: Alexithymia: a view of the psychosomatic process – volume: 12 start-page: 169 year: 2002 ident: 10.1016/j.jad.2008.07.013_bib1 article-title: Neural systems for recognizing emotion publication-title: Curr. Opin. Neurobiol. doi: 10.1016/S0959-4388(02)00301-X – volume: 66 start-page: 132 year: 2004 ident: 10.1016/j.jad.2008.07.013_bib23 article-title: Alexithymia correlates with the size of the right anterior cingulate publication-title: Psychosom. Med. doi: 10.1097/01.PSY.0000097348.45087.96 – volume: 74 start-page: 240 year: 2005 ident: 10.1016/j.jad.2008.07.013_bib53 article-title: Alexithymia and interpersonal problems publication-title: Psychother. Psychosom. doi: 10.1159/000085148 – volume: 41 start-page: 551 year: 1996 ident: 10.1016/j.jad.2008.07.013_bib11 article-title: Cross validation of the factor structure of the 20-item Toronto Alexithymia Scale: an Italian multicenter study publication-title: J. Psychosom. Res. doi: 10.1016/S0022-3999(96)00228-0 – volume: 118 start-page: 279 year: 1995 ident: 10.1016/j.jad.2008.07.013_bib16 article-title: Contributions of anterior cingulate cortex to behaviour publication-title: Brain doi: 10.1093/brain/118.1.279 – volume: 96 start-page: 5268 year: 1999 ident: 10.1016/j.jad.2008.07.013_bib36 article-title: A neuronal morphologic type unique to humans and great apes publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.96.9.5268 – volume: 150 start-page: 1105 year: 1993 ident: 10.1016/j.jad.2008.07.013_bib41 article-title: Alexithymia in panic disorder and simple phobia: a comparative study publication-title: Am. J. Psychiatry doi: 10.1176/ajp.150.7.1105 – volume: 129 start-page: 564 year: 2006 ident: 10.1016/j.jad.2008.07.013_bib14 article-title: The precuneus: a review of its functional anatomy and behavioural correlates publication-title: Brain doi: 10.1093/brain/awl004 – volume: 54 start-page: 504 year: 2003 ident: 10.1016/j.jad.2008.07.013_bib44 article-title: Neurobiology of emotion perception I: the neural basis of normal emotion perception publication-title: Biol. Psychiatry doi: 10.1016/S0006-3223(03)00168-9 – volume: 159 start-page: 961 year: 2002 ident: 10.1016/j.jad.2008.07.013_bib10 article-title: Effect of impaired recognition and expression of emotions on frontocingulate cortices: an fMRI study of men with alexithymia publication-title: Am. J. Psychiatry doi: 10.1176/appi.ajp.159.6.961 – volume: 22 start-page: 255 year: 1973 ident: 10.1016/j.jad.2008.07.013_bib52 article-title: The prevalence of alexithymic characteristics in psychosomatic patients publication-title: Psychother. Psychosom. doi: 10.1159/000286529 – volume: 42 start-page: 471 year: 2001 ident: 10.1016/j.jad.2008.07.013_bib29 article-title: Prevalence and sociodemographic correlates of alexithymia in a population sample of young adults publication-title: Compr. Psychiatry doi: 10.1053/comp.2001.27892 – year: 1997 ident: 10.1016/j.jad.2008.07.013_bib56 – volume: 112 start-page: 103 year: 1996 ident: 10.1016/j.jad.2008.07.013_bib22 article-title: Localization of grasp representations in humans by positron emission tomography. 2. Observation compared with imagination publication-title: Exp. Brain Res doi: 10.1007/BF00227183 – start-page: 263 year: 1994 ident: 10.1016/j.jad.2008.07.013_bib17 article-title: An MRI-based probabilistic atlas of neuroanatomy – volume: 32 start-page: 153 year: 1991 ident: 10.1016/j.jad.2008.07.013_bib54 article-title: The alexithymia construct. A potential paradigm for psychosomatic medicine publication-title: Psychosomatics doi: 10.1016/S0033-3182(91)72086-0 – volume: 2 start-page: 79 year: 2003 ident: 10.1016/j.jad.2008.07.013_bib6 article-title: Computer-assisted imaging to assess brain structure in healthy and diseased brains publication-title: Lancet Neurol. doi: 10.1016/S1474-4422(03)00304-1 |
| SSID | ssj0006970 |
| Score | 2.228284 |
| Snippet | Alexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions. Aim of this study... AbstractBackgroundAlexithymia relates to difficulty recognizing and describing own feelings. Recent literature shows that specific structures process emotions.... |
| SourceID | proquest pubmed pascalfrancis crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 208 |
| SubjectTerms | Adult Adult and adolescent clinical studies Affective Symptoms - diagnosis Affective Symptoms - pathology Aged Alexithymia Analysis of Variance Biological and medical sciences Brain - pathology Cortex Emotions Female Frontal Lobe - pathology Functional Laterality Gyrus Cinguli - pathology Healthy subjects Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Medical sciences Middle Aged Mood disorders Morphology MRI Neuroimaging Psychiatric Status Rating Scales Psychiatric/Mental Health Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry TAS-20 Temporal Lobe - pathology Voxel-based morphometry Women |
| Title | Alexithymia in healthy women: A brain morphology study |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0165032708002942 https://www.clinicalkey.es/playcontent/1-s2.0-S0165032708002942 https://dx.doi.org/10.1016/j.jad.2008.07.013 https://www.ncbi.nlm.nih.gov/pubmed/18718670 https://www.proquest.com/docview/57276510 https://www.proquest.com/docview/66927036 |
| Volume | 114 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEBZpcimU0NKX22arQ08FZy3rYSu3JSRsuzSHtqG5Cb0MDol3qTeHXPrbM5LlLaHdFHoyGA2WP4--GVnzQOiD57U3tZE5mBOdMy99LrkzuTXON5pQbmL3hi9nYn7OPl_wix10PObChLDKxP0Dp0e2TnemCc3pqm2n30IiTkHLKvo8kgEP75VUClDtvdmnxfxsQ8hCxp5xYXweBMbDzRjmdaldiqisDgtCt5mnJyvdA2jN0O1iuzsazdLpU7Sf_Ek8G6b8DO347jkSIW2lhU9w3WrcdnhIdrzFsdzCEZ5hExpD4OslgBx_q-NYZfYFOj89-X48z1ODhNzymq5zYmntwL7U1ktXCk5dZXXDaNXw0lIf9mYE_LuKAe7E6po5EuqReWMMZaUz9CXa7Zadf40wWLDGWU-F5Y5pTnTlayeFLRrnYMnTDBUjLsqm6uGhicWVGsPELhVAmbpaVgqgzNDHjchqKJ3x0OByBFuNOaHAYgqI_SGh6m9Cvk_rsFdE9aUq1B-6kiG2kbynbv964OSeHmzeC-BjFDaHGXo_KoaCdRoOX3Tnlze94uAoCiDA7SOEkGUoh5ahV4NG_UYNdrW1qIo3_zfrt-jxeAZWkHdod_3zxh-AK7U2E_To8BeZpAUTrouvPxZ3U-odGw |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1JT9wwFLYQPVCpQkXdQlvwgVOlMHG8Jb0hBJq2wKUgcbO8RQqCzIgMBy797X12nEGoDEi9Ru8pzue3OX4LQnueV95Ups7Bneic-drnNXcmt8b5RhPKTZzecHomphfs5yW_XEOHYy1MSKtMtn-w6dFapyeThOZk3raT36EQp6CljDFPzcAOv2KgvkE79_885HmIOk6MC9R5IB-vNmOS15V2KZ9S7heErnJOb-a6B8iaYdbF6mA0OqXjt2gzRZP4YFjwFlrz3TskQtFKCxtw02rcdngodbzHsdnCd3yATRgLgW9mAHH8qY5jj9n36OL46PxwmqfxCLnlFV3kxNLKgXeprK9dKTh10uqGUdnw0lIfTmYEojvJAHVidcUcCd3IvDGGstIZ-gGtd7POf0IY_FfjrKfCcsc0J1r6ytXCFo1zoPA0Q8WIi7Kpd3gYYXGtxiSxKwVQppmWUgGUGfq2ZJkPjTOeIy5HsNVYEQo2TIFZf45JPsXk-6SFvSKqL1Wh_pGUDLEl5yNhe-mFO4_kYPldAB-jcDTM0O4oGAq0NFy96M7P7nrFIUwUYP5WUwhRl6EZWoY-DhL1gBqcaSshi-3_W_Uu2pien56okx9nvz6j1-NtWEG-oPXF7Z3_CkHVwuxEpfkLwagcPA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Alexithymia+in+healthy+women+%3A+A+brain+morphology+study&rft.jtitle=Journal+of+affective+disorders&rft.au=BORSCI%2C+Genoveffa&rft.au=BOCCARDI%2C+Marina&rft.au=ROSSI%2C+Roberta&rft.au=ROSSI%2C+Giuseppe&rft.date=2009-04-01&rft.pub=Elsevier&rft.issn=0165-0327&rft.volume=114&rft.issue=1-3&rft.spage=208&rft.epage=215&rft_id=info:doi/10.1016%2Fj.jad.2008.07.013&rft.externalDBID=n%2Fa&rft.externalDocID=21243862 |
| thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F01650327%2FS0165032709X00030%2Fcov150h.gif |