Negative impact of porcine circovirus type 2 infection on the efficacy of classical swine fever vaccine in a field farm

• Published in: Journal of Veterinary Medical Science Vol. 87; no. 5; pp. 509 - 516
• Main Authors: KUWATA, Keisuke, OTSU, Keko, INOHA, Shuko, KIMURA, Yoko, AOKI, Hiroshi, SAKODA, Yoshihiro
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2025; 公益社団法人 日本獣医学会; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Animals; Antibodies; Antibodies, Neutralizing - blood; Antibodies, Viral - blood; Circoviridae Infections - immunology; Circoviridae Infections - veterinary; Circoviridae Infections - virology; Circovirus - immunology; Classical Swine Fever - immunology; Classical Swine Fever - prevention & control; Classical Swine Fever - virology; classical swine fever virus; Classical Swine Fever Virus - immunology; Farms; Fever; Hog cholera; Hogs; Immune response; Immunosuppression; Infections; Japan - epidemiology; Mortality; porcine circovirus type 2; porcine circovirus-associated disease; Swine; vaccination; Vaccination - veterinary; Vaccine Efficacy; Vaccines; Viral Load - veterinary; Viral Vaccines - immunology; Virology; Japan; porcine circovirus type 2; classical swine fever virus; immunosuppression; porcine circovirus-associated disease; vaccination

Porcine circovirus type 2 (PCV2) induces wasting and immunosuppression in pigs and is widely transmitted in pig farms worldwide. Classical swine fever (CSF) is a particularly important contagious disease in pigs. In CSF-endemic areas, such as Japan, thorough vaccination is performed, and effective u...