From crystal structure to in silico epitope discovery in the Burkholderia pseudomallei flagellar hook‐associated protein FlgK - Gourlay, Louise J; Thomas, Rachael J; Peri, Claudio; Conchillo‐Solé, Oscar; Ferrer‐Navarro, Mario; Nithichanon, Arnone; Vila, Jordi; Daura, Xavier; Lertmemongkolchai, Ganjana; Titball, Richard; Colombo, Giorgio; Bolognesi, Martino (The FEBS journal, 2015)
Keywords: Amino Acid Sequence; Animals; antibiotics; antibodies; Antibodies, Bacterial - blood; antigen; Antigens, Bacterial - chemistry; antiserum; Australia; bacterial motility; Bacterial Proteins - chemistry; Bacterial Proteins - immunology; Bacterial Proteins - physiology; Burkholderia pseudomallei; Burkholderia pseudomallei - immunology; Burkholderia pseudomallei; Cell Line; Computer Simulation; Crystal structure; Crystallography, X-Ray; cytotoxicity; engineering; epitope discovery; epitopes; Epitopes - chemistry; flagellar hook‐associated protein; flagellin; flagellum; Gram-negative bacteria; Humans; Immunoglobulins; macrophages; Macrophages - immunology; Macrophages - microbiology; melioidosis; Melioidosis - blood; Melioidosis - immunology; Melioidosis - microbiology; Mice; Models, Molecular; Molecular Sequence Data; pathogenesis; patients; prediction; protein subunits; Proteins; seroprevalence; South East Asia; structural vaccinology; Vaccines; virulence; South East Asia; Australia; flagellar hook-associated protein; antigen; epitope discovery; structural vaccinology; Burkholderia pseudomallei