Evaluation of the redox state in mouse organs following radon inhalation

• Published in: Journal of radiation research Vol. 62; no. 2; pp. 206 - 216
• Main Authors: Kataoka, Takahiro, Kanzaki, Norie, Sakoda, Akihiro, Shuto, Hina, Yano, Junki, Naoe, Shota, Tanaka, Hiroshi, Hanamoto, Katsumi, Terato, Hiroaki, Mitsunobu, Fumihiro, Yamaoka, Kiyonori
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.03.2021
• Subjects: Administration, Inhalation; Analysis; Animals; Antioxidants; Antioxidants - metabolism; Catalase - metabolism; Fundamental Radiation Science; Glutathione - metabolism; Hydrogen Peroxide - metabolism; Lipid Peroxides - metabolism; Male; Mice; Mice, Inbred BALB C; Organ Specificity - radiation effects; Oxidation-Reduction - radiation effects; Peroxides; Principal Component Analysis; Radon - administration & dosage; Superoxide; Superoxide Dismutase - metabolism; Japan; radon; redox state; antioxidative function; oxidative stress; principal component analysis

Radon inhalation activates antioxidative functions in mouse organs, thereby contributing to inhibition of oxidative stress-induced damage. However, the specific redox state of each organ after radon inhalation has not been reported. Therefore, in this study, we evaluated the redox state of various o...