Early prediction of pathologic response to neoadjuvant therapy in breast cancer: Systematic review of the accuracy of MRI

• Published in: Breast (Edinburgh) Vol. 21; no. 5; pp. 669 - 677
• Main Authors: Marinovich, M.L., Sardanelli, F., Ciatto, S., Mamounas, E., Brennan, M., Macaskill, P., Irwig, L., von Minckwitz, G., Houssami, N.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.10.2012
• Subjects: Anthracyclines - administration & dosage; Antineoplastic Agents - administration & dosage; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Breast cancer; Breast Neoplasms - drug therapy; Breast Neoplasms - pathology; Carcinoma, Ductal, Breast - drug therapy; Carcinoma, Ductal, Breast - pathology; Chemotherapy, Adjuvant; Female; Hematology, Oncology and Palliative Medicine; Humans; Magnetic Resonance Imaging; Mastectomy; Neoadjuvant Therapy; Patient monitoring; Sensitivity and Specificity; Taxoids - administration & dosage; Treatment Outcome; Sensitivity and specificity; Neoadjuvant therapy; Patient monitoring; Breast cancer; Magnetic resonance imaging
• ISSN: 0960-9776; 1532-3080; 1532-3080
• DOI: 10.1016/j.breast.2012.07.006

Magnetic resonance imaging (MRI) has been proposed to have a role in predicting final pathologic response when undertaken early during neoadjuvant chemotherapy (NAC) in breast cancer. This paper examines the evidence for MRI's accuracy in early response prediction. A systematic literature searc...