Imaging biomarkers of NAFLD, NASH, and fibrosis

• Published in: Molecular metabolism (Germany) Vol. 50; p. 101167
• Main Authors: Ajmera, Veeral, Loomba, Rohit
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.08.2021; Elsevier
• Subjects: Biopsy; Disease Progression; Elasticity Imaging Techniques - methods; Humans; Liver - diagnostic imaging; Liver - pathology; Liver Cirrhosis - diagnosis; Liver Cirrhosis - pathology; Magnetic Resonance Imaging - methods; MR Elastography; MRI; MRI-PDFF; NAFLD; NASH; Non-alcoholic Fatty Liver Disease - diagnosis; Non-alcoholic Fatty Liver Disease - pathology; Review; Severity of Illness Index; Significant fibrosis; NAFLD; NASH; Significant fibrosis; MRI; MR Elastography; MRI-PDFF

Non-alcoholic fatty liver disease (NAFLD) is a clinicopathologic entity that requires a liver biopsy assessment to diagnose the progressive form of NAFLD called non-alcoholic steatohepatitis (NASH). Liver biopsy is invasive, subject to sampling and interobserver variability, and impractical to scale...