Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome

• Published in: Trends in molecular medicine Vol. 27; no. 9; pp. 895 - 906
• Main Authors: Komaroff, Anthony L., Lipkin, W. Ian
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2021
• Subjects: COVID-19; COVID-19 - complications; COVID-19 - etiology; COVID-19 - physiopathology; Energy Metabolism; Fatigue Syndrome, Chronic - etiology; Fatigue Syndrome, Chronic - physiopathology; Gastrointestinal Microbiome; Humans; long COVID; myalgic encephalomyelitis/chronic fatigue syndrome; Nervous System - physiopathology; Post-Acute COVID-19 Syndrome; postacute sequelae of SARS-CoV-2; post–COVID-19 syndrome; Review; SARS-CoV-2; COVID-19; SARS-CoV-2; postacute sequelae of SARS-CoV-2; long COVID; post–COVID-19 syndrome; myalgic encephalomyelitis/chronic fatigue syndrome
• ISSN: 1471-4914; 1471-499X; 1471-499X
• DOI: 10.1016/j.molmed.2021.06.002

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause chronic and acute disease. Postacute sequelae of SARS-CoV-2 infection (PASC) include injury to the lungs, heart, kidneys, and brain that may produce a variety of symptoms. PASC also includes a post–coronavirus disease 2019 (COVID...