Complement C5a/C5aR pathway potentiates the pathogenesis of gastric cancer by down-regulating p21 expression - Chen, Jian; Li, Gui-qing; Zhang, Li; Tang, Ming; Cao, Xu; Xu, Gui-lian; Wu, Yu-Zhang (Cancer letters, 2018)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Animals; Breast cancer; Cancer therapies; Cell cycle; Cell Line, Tumor; Complement C5a - physiology; Complement C5a/C5aR; Complement component C5a; Cyclin-dependent kinase inhibitor p21; Cyclin-Dependent Kinase Inhibitor p21 - antagonists & inhibitors; Cyclin-Dependent Kinase Inhibitor p21 - physiology; Down-Regulation; Female; Flow cytometry; Gastric cancer; Gene expression; Humans; Male; Medical prognosis; Metastasis; Mice; p21; Pathogenesis; Phosphatidylinositol 3-Kinases - physiology; PI3K/AKT; Proto-Oncogene Proteins c-akt - physiology; Receptor, Anaphylatoxin C5a - physiology; Signal transduction; Signal Transduction - physiology; Stomach Neoplasms - etiology; Tumors; United States--US; China; Complement C5a/C5aR; Gastric cancer; p21; PI3K/AKT