m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in Gastrointestinal Cancer

• Published in: Translational oncology Vol. 12; no. 10; pp. 1323 - 1333
• Main Authors: Zhao, Yueshui, Zhao, Qijie, Kaboli, Parham Jabbarzadeh, Shen, Jing, Li, Mingxing, Wu, Xu, Yin, Jianhua, Zhang, Hanyu, Wu, Yuanlin, Lin, Ling, Zhang, Lingling, Wan, Lin, Wen, Qinglian, Li, Xiang, Cho, Chi Hin, Yi, Tao, Li, Jing, Xiao, Zhangang
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2019; Neoplasia Press; Elsevier
• Subjects: Original article

BACKGROUND: Gene expression can be posttranscriptionally regulated by a complex network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification. However, little is known about both its influence and biogenesis in tumor development. METHODS: This study analyzed TCGA data of patien...