VETC predicting model based on CE-CT can predict prognosis and assisting treatment plan for solitary HCC: better together with radiomics

• Published in: BMC cancer Vol. 25; no. 1; pp. 1033 - 14
• Main Authors: Zhao, Yu-Meng, Xie, Shuang-Shuang, Wang, Jian, Hu, Zhan-Dong, Yao, Sheng-Juan, Wang, Rui-Hang, Qin, Jia-Ming, Zhang, Cheng, Zhang, Ya-Min, Ye, Zhao-Xiang, Yan, Jian-Hua, Shen, Wen
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 01.07.2025; BioMed Central; BMC
• Subjects: Abdomen; Analysis; Antigens; Cancer; Care and treatment; Computed tomography; Contrast-enhanced CT; CT imaging; Diagnosis; Genetic aspects; Hepatectomy; Hepatocellular carcinoma; Hepatoma; Leukocytes (neutrophilic); Liver; Liver cancer; Liver transplantation; Lymphocytes; Magnetic resonance imaging; Medical prognosis; Metastasis; Neutrophils; Nomograms; Noninvasive evaluation; Patient outcomes; Patients; Predictive modeling; Prognosis; Radiomics; Relapse; Statistical analysis; Transplantation; Treatment plan; Tumors; Vessels that encapsulate tumor clusters pattern; γ-Glutamyltransferase; China; Contrast-enhanced CT; Hepatocellular carcinoma; Vessels that encapsulate tumor clusters pattern; Predictive modeling; Treatment plan; Radiomics

Objectives Noninvasive evaluation and treatment of vessels encapsulating tumor cluster (VETC) HCCs remain challenging. Herein, a new Clinic-Radiologic-Intratumor Radiomics (CRIR) model was investigated for the preoperative prediction of VETC-HCCs and prognosis based on CE-CT, then compared therapeut...