A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future

• Published in: Vaccine Vol. 39; no. 45; pp. 6573 - 6584
• Main Authors: Moore, Kristine A., Ostrowsky, Julia T., Kraigsley, Alison M., Mehr, Angela J., Bresee, Joseph S., Friede, Martin H., Gellin, Bruce G., Golding, Josephine P., Hart, Peter J., Moen, Ann, Weller, Charlotte L., Osterholm, Michael T., Ampofo, William, Barclay, Wendy, Cavaleri, Marco, Cohen, Cheryl, Cowling, Benjamin, Cox, Rebecca, Gust, Ian, Innis, Bruce, Kang, Gagandeep, Katz, Jacqueline, Krammer, Florian, Pitisuttithum, Punnee, Post, Diane, Rudenko, Larisa, Siqueira, Marilda, Weir, Jerry
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 29.10.2021; Elsevier Limited
• Subjects: Allergy and Immunology; Animals; Broadly protective influenza vaccines; Collaboration; Consortia; Coronaviruses; COVID-19 vaccines; finance; human influenza; Humans; Immunology; Infectious diseases; Influenza; Influenza Vaccines; Influenza, Human - epidemiology; Influenza, Human - prevention & control; issues and policy; Medical research; Orthomyxoviridae; Orthomyxoviridae Infections; Pandemic preparedness; Pandemics; Public health; R&D; Regulation; Research & development; research and development; Roadmap; Seasonal influenza vaccines; Severe acute respiratory syndrome coronavirus 2; Stakeholders; Universal influenza vaccines; vaccine development; Vaccines; Virology; Viruses; LAIV; CEPI; IVR; Universal influenza vaccines; Seasonal influenza vaccines; COBRA; ABS; HVAC; CARB-X; ME&A; CIDRAP; FVVA; CHIVIM; ADCC; WHO; CIVICs; SME; LMICs; NIAID; EU; HAI; R&D; Broadly protective influenza vaccines; Roadmap; ACT; NA; Influenza; IIV; GISRS; HA; Pandemic preparedness; US National Institute of Allergy and Infectious Diseases; hemagglutinin; inactivated influenza vaccines; heating, ventilation, and air conditioning; computationally optimized broadly reactive antigen; biopharmaceutical accelerator for combating antibiotic resistant bacteria; World Health Organization; Global Influenza Surveillance and Response System; antibody-dependent cellular cytotoxicity; neuraminidase; Collaborative Influenza Vaccine Innovation Centers; Research and Development; Access to COVID-19 Tools; controlled human influenza virus infection model; Center for Infectious Disease Research and Policy; live-attenuated influenza vaccines; monitoring, evaluation, and adjustment; Access and Benefit Sharing; low- and middle-income countries; full value of vaccine assessment; subject matter expert; Influenza Vaccines Research and Development (R&D) Roadmap; European Union; Coalition for Epidemic Preparedness Innovations; hemagglutination-inhibition

Improved influenza vaccines are urgently needed to reduce the burden of seasonal influenza and to ensure a rapid and effective public-health response to future influenza pandemics. The Influenza Vaccines Research and Development (R&D) Roadmap (IVR) was created, through an extensive international...