Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses - Milligan, Jacob C.; Davis, Carl W.; Yu, Xiaoying; Ilinykh, Philipp A.; Huang, Kai; Halfmann, Peter J.; Cross, Robert W.; Borisevich, Viktoriya; Agans, Krystle N.; Geisbert, Joan B.; Chennareddy, Chakravarthy; Goff, Arthur J.; et al. (Cell, 2022)
Keywords: Animals; Antibodies, Neutralizing; Antibodies, Viral; antibody binding sites; antibody therapeutic; BASIC BIOLOGICAL SCIENCES; Bundibugyo virus; cross reaction; cryo-EM; disease severity; Ebola virus; Ebolavirus; Epitopes; glycoproteins; Glycoproteins - chemistry; Hemorrhagic Fever, Ebola; medical countermeasure; memory; monoclonal antibodies; monoclonal antibody; nonhuman primate; Protein Subunits; Sudan; Sudan virus; viruses; Sudan; Ebola virus; Sudan virus; ebolavirus; medical countermeasure; Bundibugyo virus; nonhuman primate; monoclonal antibody; cryo-EM; antibody therapeutic