Associations of melamine and cyanuric acid exposure with markers of kidney function in adults: Results from NHANES 2003–2004

• Published in: Environment international Vol. 141; p. 105815
• Main Authors: Guo, Jianqiu, Wu, Chunhua, Zhang, Jiming, Chang, Xiuli, Zhang, Yubin, Cao, Yang, Zhou, Zhijun
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.08.2020; Elsevier
• Subjects: Adult; average daily intake; Biomonitoring; body mass index; body weight; Chromatography, Liquid; confidence interval; creatinine; Cyanuric acid; environment; excretion; glomerular filtration rate; Humans; hypertension; Kidney; Kidney function; kidneys; liquid chromatography; Melamine; National Health and Nutrition Examination Survey; nephrotoxicity; NHANES; Nutrition Surveys; regression analysis; renal calculi; risk; Tandem Mass Spectrometry; Triazines - toxicity; Cyanuric acid; Biomonitoring; NHANES; Melamine; Kidney function

•Melamine was nearly ubiquitous with a geometric mean of 1.38 μg/L in U.S. adults.•A novel method for covariate-adjusted creatinine standardization was applied.•Individuals with high melamine exposure had lower eGFR than those with low melamine exposure. Higher melamine exposure may increase the ris...