A systematic review of the safety of topical therapies for atopic dermatitis

• Published in: British journal of dermatology (1951) Vol. 156; no. 2; pp. 203 - 221
• Main Authors: Callen, J., Chamlin, S., Eichenfield, L.F., Ellis, C., Girardi, M., Goldfarb, M., Hanifin, J., Lee, P., Margolis, D., Paller, A.S., Piacquadio, D., Peterson, W., Kaulback, K., Fennerty, M., Wintroub, B.U.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.02.2007; Blackwell
• Subjects: Administration, Topical; Adrenal Cortex Hormones - adverse effects; Adrenal Cortex Hormones - pharmacokinetics; Allergic diseases; Anti-Bacterial Agents - adverse effects; Anti-Bacterial Agents - pharmacokinetics; Anti-Inflammatory Agents - adverse effects; Anti-Inflammatory Agents - pharmacokinetics; atopic dermatitis; Biological and medical sciences; Bones, joints and connective tissue. Antiinflammatory agents; calcineurin inhibitors; Cost of Illness; Dermatitis, Atopic - drug therapy; Dermatitis, Atopic - metabolism; Dermatology; Humans; Immunopathology; Immunosuppressive Agents - adverse effects; Immunosuppressive Agents - pharmacokinetics; Medical sciences; Pharmacology. Drug treatments; safety; Skin allergic diseases. Stinging insect allergies; steroids; Human; Allergy; Immunopathology; Corticosteroid; Skin disease; Calcineurin inhibitor; Dermatology; Toxicity; Systematic review; Evidence-based medicine; Atopy; calcineurin inhibitors; Local administration; Chemotherapy; Treatment; Atopic dermatitis; safety; steroids

Summary Background  The safety of topical therapies for atopic dermatitis (AD), a common and morbid disease, has recently been the focus of increased scrutiny, adding confusion as how best to manage these patients. Objectives  The objective of these systematic reviews was to determine the safety of...