Optimal adaptive allocation using deep reinforcement learning in a dose‐response study - Matsuura, Kentaro; Honda, Junya; El Hanafi, Imad; Sozu, Takashi; Sakamaki, Kentaro (Statistics in medicine, 2022)
Keywords: adaptive design; Business metrics; clinical trial; Computer Science; Computer Simulation; Deep learning; Dose-Response Relationship, Drug; dose‐finding; dose‐ranging; Drug Development; Humans; Life Sciences; Machine Learning; optimal design; Pharmaceutical sciences; Research Design; response‐adaptive; Sample Size; clinical trial; optimal design; dose-ranging; response-adaptive; adaptive design; dose-finding