Off-pump coronary artery bypass grafting improves short-term outcomes in high-risk patients compared with on-pump coronary artery bypass grafting: Meta-analysis

• Published in: The Journal of thoracic and cardiovascular surgery Vol. 151; no. 1; pp. 60 - 77.e58
• Main Authors: Kowalewski, Mariusz, Pawliszak, Wojciech, Malvindi, Pietro Giorgio, Bokszanski, Marek Pawel, Perlinski, Damian, Raffa, Giuseppe Maria, Kowalkowska, Magdalena Ewa, Zaborowska, Katarzyna, Navarese, Eliano Pio, Kolodziejczak, Michalina, Kowalewski, Janusz, Tarelli, Giuseppe, Taggart, David Paul, Anisimowicz, Lech
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2016
• Subjects: Aged; Aged, 80 and over; cardiopulmonary bypass; Cardiopulmonary Bypass - adverse effects; Cardiopulmonary Bypass - mortality; Cardiothoracic Surgery; cerebrovascular disorders; Chi-Square Distribution; Coronary Artery Bypass - adverse effects; Coronary Artery Bypass - methods; Coronary Artery Bypass - mortality; Coronary Artery Bypass, Off-Pump - adverse effects; Coronary Artery Bypass, Off-Pump - mortality; Coronary Artery Disease - diagnosis; Coronary Artery Disease - mortality; Coronary Artery Disease - surgery; coronary disease; Female; Hospital Mortality; Humans; Linear Models; Male; Middle Aged; Myocardial Infarction - etiology; Myocardial Infarction - mortality; Odds Ratio; Patient Selection; Protective Factors; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Stroke - etiology; Stroke - mortality; Time Factors; Treatment Outcome; ROOBY; 23; 45; RCT; OR; 25; ECC; CORONARY; CI; 28; CAD; PRISMA; coronary disease; NNT; PCI; cardiopulmonary bypass; EuroSCORE; cerebrovascular disorders; CABG; MI; OPCAB; Myocardial infarction; European System for Cardiac Operative Risk Evaluation; Percutaneous coronary intervention; Preferred Reporting Items for Systematic Reviews and Meta-Analyses; Extracorporeal circulation; Number needed to treat; Coronary artery bypass grafting; Veterans Affairs Randomized On/Off Bypass Trial; Coronary artery disease; Randomized controlled trial; Confidence interval; CABG Off or On Pump Revascularization Study; Odds ratio; Off-pump coronary artery bypass

To assess the benefits and risks of off-pump coronary artery bypass (OPCAB) versus coronary artery bypass grafting (CABG) through a meta-analysis of randomized controlled trials (RCTs), and to investigate the relationship between outcomes and patient risk profile. PubMed, Embase, the Cumulative Inde...