Mechanisms of FSH synthesis: what we know, what we don't, and why you should care

The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive physiology. Though the two hormones are produced by the same cell type, often in response to the same endocrine and paracrine regulators, they sub-serve different biological functions and their synthesis and secretio...

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Published inFertility and sterility Vol. 93; no. 8; pp. 2465 - 2485
Main Authors Bernard, Daniel J., Fortin, Jérôme, Wang, Ying, Lamba, Pankaj
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 15.05.2010
Elsevier
Subjects
Activins - physiology
Androgens - physiology
Animals
Base Sequence
Biological and medical sciences
Cell Line
Estrogens - physiology
Female
Follicle Stimulating Hormone, beta Subunit - biosynthesis
Follicle Stimulating Hormone, beta Subunit - secretion
Follistatin - physiology
GATA2 Transcription Factor - physiology
Gene Expression Regulation
Glycoprotein Hormones, alpha Subunit
Gonadotrophs - metabolism
Gonadotropin-Releasing Hormone - physiology
Gynecology. Andrology. Obstetrics
Homeodomain Proteins - genetics
Homeodomain Proteins - physiology
Humans
Inhibins - physiology
Internal Medicine
LIM-Homeodomain Proteins
Male
Medical sciences
Molecular Sequence Data
Obstetrics and Gynecology
Paired Box Transcription Factors - physiology
Promoter Regions, Genetic - physiology
Sequence Alignment
Species Specificity
Steroidogenic Factor 1 - physiology
Transcription Factors
Synthesis
Obstetrics
Gynecology
Follicle stimulating hormone
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Abstract The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive physiology. Though the two hormones are produced by the same cell type, often in response to the same endocrine and paracrine regulators, they sub-serve different biological functions and their synthesis and secretion are differentially regulated. This stems largely from differences in transcriptional, post-transcriptional, and post-translational regulation of their unique β subunits. That is, both hormones are dimeric glycoproteins and share a common α subunit. Their unique β subunits, however, derive from different genes encoding distinct proteins. Past and recent research indicates synthesis and release of the two hormones are subject to extensive and independent regulation. LH appears to be secreted predominantly via the regulated secretory pathway, whereas FSH release is largely constitutive. As such, investigations of FSH-β subunit synthesis may lend direct insight into mechanisms underlying patterns of secreted FSH, more so than investigations of the LHβ subunit. Here, we review recent investigations of transcriptional regulation of the FSH-β subunit gene from different mammalian species, including humans. The results reveal both conserved and species-specific regulatory mechanisms that might contribute to inter-species variation in FSH release.
AbstractList The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive physiology. Though the two hormones are produced by the same cell type, often in response to the same endocrine and paracrine regulators, they sub-serve different biological functions and their synthesis and secretion are differentially regulated. This stems largely from differences in transcriptional, post-transcriptional, and post-translational regulation of their unique β subunits. That is, both hormones are dimeric glycoproteins and share a common α subunit. Their unique β subunits, however, derive from different genes encoding distinct proteins. Past and recent research indicates synthesis and release of the two hormones are subject to extensive and independent regulation. LH appears to be secreted predominantly via the regulated secretory pathway, whereas FSH release is largely constitutive. As such, investigations of FSH-β subunit synthesis may lend direct insight into mechanisms underlying patterns of secreted FSH, more so than investigations of the LHβ subunit. Here, we review recent investigations of transcriptional regulation of the FSH-β subunit gene from different mammalian species, including humans. The results reveal both conserved and species-specific regulatory mechanisms that might contribute to inter-species variation in FSH release.
The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive physiology. Though the two hormones are produced by the same cell type, often in response to the same endocrine and paracrine regulators, they sub-serve different biological functions and their synthesis and secretion are differentially regulated. This stems largely from differences in transcriptional, post-transcriptional, and post-translational regulation of their unique beta subunits. That is, both hormones are dimeric glycoproteins and share a common alpha subunit. Their unique beta subunits, however, derive from different genes encoding distinct proteins. Past and recent research indicates synthesis and release of the two hormones are subject to extensive and independent regulation. LH appears to be secreted predominantly via the regulated secretory pathway, whereas FSH release is largely constitutive. As such, investigations of FSH-beta subunit synthesis may lend direct insight into mechanisms underlying patterns of secreted FSH, more so than investigations of the LHbeta subunit. Here, we review recent investigations of transcriptional regulation of the FSH-beta subunit gene from different mammalian species, including humans. The results reveal both conserved and species-specific regulatory mechanisms that might contribute to inter-species variation in FSH release.
The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive physiology. Though the two hormones are produced by the same cell type, often in response to the same endocrine and paracrine regulators, they sub-serve different biological functions and their synthesis and secretion are differentially regulated. This stems largely from differences in transcriptional, post-transcriptional, and post-translational regulation of their unique beta subunits. That is, both hormones are dimeric glycoproteins and share a common alpha subunit. Their unique beta subunits, however, derive from different genes encoding distinct proteins. Past and recent research indicates synthesis and release of the two hormones are subject to extensive and independent regulation. LH appears to be secreted predominantly via the regulated secretory pathway, whereas FSH release is largely constitutive. As such, investigations of FSH-beta subunit synthesis may lend direct insight into mechanisms underlying patterns of secreted FSH, more so than investigations of the LHbeta subunit. Here, we review recent investigations of transcriptional regulation of the FSH-beta subunit gene from different mammalian species, including humans. The results reveal both conserved and species-specific regulatory mechanisms that might contribute to inter-species variation in FSH release.The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive physiology. Though the two hormones are produced by the same cell type, often in response to the same endocrine and paracrine regulators, they sub-serve different biological functions and their synthesis and secretion are differentially regulated. This stems largely from differences in transcriptional, post-transcriptional, and post-translational regulation of their unique beta subunits. That is, both hormones are dimeric glycoproteins and share a common alpha subunit. Their unique beta subunits, however, derive from different genes encoding distinct proteins. Past and recent research indicates synthesis and release of the two hormones are subject to extensive and independent regulation. LH appears to be secreted predominantly via the regulated secretory pathway, whereas FSH release is largely constitutive. As such, investigations of FSH-beta subunit synthesis may lend direct insight into mechanisms underlying patterns of secreted FSH, more so than investigations of the LHbeta subunit. Here, we review recent investigations of transcriptional regulation of the FSH-beta subunit gene from different mammalian species, including humans. The results reveal both conserved and species-specific regulatory mechanisms that might contribute to inter-species variation in FSH release.
Author Fortin, Jérôme
Wang, Ying
Lamba, Pankaj
Bernard, Daniel J.
Author_xml – sequence: 1
  givenname: Daniel J.
  surname: Bernard
  fullname: Bernard, Daniel J.
  email: daniel.bernard@mcgill.ca
– sequence: 2
  givenname: Jérôme
  surname: Fortin
  fullname: Fortin, Jérôme
– sequence: 3
  givenname: Ying
  surname: Wang
  fullname: Wang, Ying
– sequence: 4
  givenname: Pankaj
  surname: Lamba
  fullname: Lamba, Pankaj
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22854393$$DView record in Pascal Francis
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Cites_doi 10.1210/me.2002-0286
10.1002/jcp.20598
10.1095/biolreprod46.2.220
10.1074/jbc.M207824200
10.1095/biolreprod62.3.636
10.1210/me.2005-0378
10.1677/joe.0.1740179
10.1210/edrv-9-2-267
10.1016/S0303-7207(02)00037-0
10.1016/j.yfrne.2008.07.001
10.1210/endo.139.7.6091
10.1016/j.peptides.2008.08.022
10.1210/mend-4-5-721
10.1126/science.272.5264.1004
10.1016/0006-291X(90)91282-W
10.1210/endo-108-2-673
10.1016/S1097-2765(00)80061-1
10.1056/NEJM199806113382404
10.1016/j.mce.2006.03.035
10.1210/en.2008-0220
10.1210/endo-124-1-552
10.1016/j.peptides.2008.08.013
10.1095/biolreprod.108.074211
10.1074/jbc.M203639200
10.1210/endo.143.6.8857
10.1210/en.2004-1317
10.1210/mend-2-7-641
10.1038/269338a0
10.1210/endo.137.8.8754772
10.1242/dev.128.2.147
10.1016/j.ymgme.2006.03.005
10.1210/jcem-72-6-1286
10.1210/endo.143.8.8962
10.1016/j.fertnstert.2004.06.069
10.1095/biolreprod.105.049049
10.1210/endo-118-3-1148
10.1126/science.7624775
10.1074/jbc.M305350200
10.1210/me.2008-0324
10.1210/en.2003-1418
10.1038/ng0297-205
10.1210/mend.13.12.0395
10.1210/endo-128-1-509
10.1210/endo.133.1.8319576
10.1210/endo.142.6.8203
10.1016/j.mce.2007.11.006
10.1210/en.2005-0490
10.1016/S0014-5793(01)02651-5
10.1677/joe.1.06923
10.1210/en.2007-1498
10.1159/000070896
10.1677/jme.1.01961
10.1128/MCB.19.4.2567
10.1016/S0303-7207(02)00223-X
10.1210/me.2005-0052
10.1111/j.1749-6632.2001.tb03788.x
10.1016/j.peptides.2008.06.029
10.1073/pnas.82.23.8203
10.1242/dev.129.2.329
10.1126/science.3125611
10.1006/bbrc.1993.1835
10.1677/JOE-07-0542
10.1210/me.2003-0115
10.1038/374356a0
10.1210/en.2004-0257
10.1095/biolreprod.108.070987
10.1016/j.mce.2007.10.003
10.1210/endo-123-6-2946
10.1210/endo.142.6.8202
10.1210/mend-3-3-474
10.1210/me.2006-0392
10.1210/mend-1-11-849
10.1093/molehr/gan079
10.1128/MCB.24.21.9383-9389.2004
10.1074/jbc.M806676200
10.1677/joe.0.1590103
10.1016/0003-9861(86)90033-0
10.1051/rnd:2005028
10.1016/j.mce.2005.12.006
10.1095/biolreprod.108.075259
10.1210/en.2007-1113
10.1016/0092-8674(95)90201-5
10.1210/endo.130.6.1534542
10.1016/0006-291X(92)91890-3
10.1152/ajpendo.00447.2006
10.1210/mend-2-6-512
10.1210/en.2007-1084
10.1210/me.2007-0455
10.1093/humrep/den216
10.1007/400_2007_050
10.1186/1477-7827-4-52
10.1016/S0092-8674(00)81600-1
10.1210/jcem-68-2-397
10.1210/en.2007-0425
10.1210/endo.137.1.8536646
10.1210/mend-5-7-949
10.1677/joe.0.1450387
10.1210/en.2004-0598
10.1530/eje.0.1390469
10.1038/nature02006
10.1016/0006-291X(88)90699-7
10.1210/en.2002-221140
10.1210/endo.139.11.6281
10.1210/endo-128-3-1682
10.1056/NEJMoa0900136
10.1124/mol.62.1.58
10.1016/S0015-0282(02)04682-4
10.1023/A:1011431123208
10.1210/me.2005-0047
10.1074/jbc.273.24.14712
10.1210/jcem-73-3-609
10.1210/endo.136.3.7867558
10.1515/CCLM.1998.118
10.1677/joe.0.1730001
10.1210/endo.143.5.8771
10.1210/endo-125-5-2787
10.1210/endo.138.6.5161
10.1016/j.mce.2007.04.009
10.1111/j.1365-2265.1992.tb01457.x
10.1210/endo.142.1.7881
10.1210/endo.141.11.7765
10.1210/endo.142.6.8185
10.1210/endo.138.6.5205
10.1126/science.3024317
10.1677/joe.1.06965
10.1210/endo.138.7.5279
10.1677/jme.1.01936
10.1677/joe.1.05988
10.1073/pnas.86.12.4501
10.1210/endo-124-5-2193
10.1101/gad.13.4.484
10.1126/science.8385366
10.1074/jbc.M304697200
10.1101/gad.8.19.2302
10.1128/MCB.00248-07
10.1016/S0303-7207(03)00235-1
10.1210/endo.139.5.6015
10.1177/42.8.8027530
10.1128/MCB.20.16.6127-6137.2000
10.1002/j.1939-4640.1994.tb00435.x
10.1210/endo.142.6.8159
10.1095/biolreprod32.2.391
10.1016/0006-291X(87)91614-7
10.1095/biolreprod64.2.714
10.1210/en.2002-220929
10.1210/me.2004-0475
10.1101/gad.12.6.844
10.1210/me.2005-0316
10.1038/emboj.2009.205
10.1126/science.1734523
10.1210/jcem-72-6-1261
10.1002/1526-968X(200011/12)28:3/4<167::AID-GENE120>3.0.CO;2-N
10.1016/S0092-8674(00)80770-9
10.1677/joe.0.162r001
10.1016/S0021-9258(18)67116-9
10.1016/S0021-9258(19)83610-4
10.1101/gad.8.4.414
10.1210/endo-125-2-917
10.1016/S0092-8674(01)00282-3
10.1074/jbc.272.21.13835
10.1242/dev.122.10.3319
10.1095/biolreprod.104.035196
10.1210/en.2005-0457
10.1210/endo-127-6-2869
10.1210/me.2007-0247
10.1095/biolreprod.107.065466
10.1016/j.peptides.2008.08.009
10.1159/000126889
10.1038/ng0297-201
10.1073/pnas.95.23.13612
10.1159/000054547
10.1210/mend-3-12-1969
10.1677/jme.1.02196
10.1530/rep.1.00195
10.1210/jc.2004-1319
10.1210/en.2009-0455
10.1210/en.2007-1502
10.1210/en.2006-1635
10.1038/35006129
10.1210/me.2003-0442
10.1095/biolreprod50.4.888
10.1074/jbc.274.37.26563
10.1016/j.devcel.2005.09.008
10.1093/humrep/14.5.1190
10.1242/dev.124.14.2807
10.1016/j.fertnstert.2003.07.030
10.1146/annurev.physiol.67.040403.115914
10.1210/en.2007-1807
10.1210/endo.137.9.8756531
10.1074/jbc.274.20.13870
10.1095/biolreprod.102.012005
10.1385/ENDO:26:3:207
10.1074/jbc.271.12.6645
10.1016/S1043-2760(00)00294-0
10.1210/me.2002-0088
10.1095/biolreprod.109.076216
10.1073/pnas.87.22.8855
10.1074/jbc.M800654200
10.1210/edrv.21.5.0409
10.1016/0303-7207(93)90091-W
10.1210/er.2003-0029
10.1210/mend-4-12-1943
10.1210/en.2006-0952
10.1002/dvg.20398
10.1210/me.2009-0030
10.1016/S0896-6273(01)80051-9
10.1016/j.mce.2004.03.009
10.1016/j.mce.2004.02.010
10.1210/me.2003-0473
10.1074/jbc.272.39.24339
10.1210/me.2003-0264
10.1016/j.mce.2006.03.024
10.1210/mend-2-12-1237
10.1210/endo-117-6-2443
10.1016/S1016-8478(23)13478-9
10.1530/rep.1.00663
10.1016/S0021-9258(19)75766-4
10.1677/joe.0.1700601
10.1186/1477-7827-7-66
10.1210/me.2006-0109
10.1095/biolreprod50.3.680
10.1016/j.mce.2003.09.019
10.1677/jme.0.0320467
10.1677/jme.1.02053
10.1210/endo-129-4-1721
10.1210/endo.131.3.1505470
10.1016/j.tem.2004.07.008
10.1158/0008-5472.SABCS-1160
10.1210/endo.140.5.6682
10.1210/endo.136.5.7720634
10.1210/me.2002-0081
10.1016/j.bcp.2004.03.045
10.1016/S0006-291X(86)80499-5
10.1093/humupd/dmn058
10.1210/me.2008-0370
10.1038/76041
10.1210/mend-4-4-597
10.1210/mend.12.3.0073
10.1126/science.100883
10.1210/endo.139.7.6111
10.1677/jme.1.01600
10.1210/en.2006-1473
10.1016/S0303-7207(02)00430-6
10.1055/s-2007-984744
10.1210/endo-113-2-535
10.1530/rep.0.1240267
10.1007/BF00271348
10.1210/en.2008-1649
10.1016/S0303-7207(97)00216-5
10.1677/JOE-07-0148
10.1210/endo.140.3.6549
10.1095/biolreprod.108.068106
ContentType Journal Article
Copyright 2010
2015 INIST-CNRS
Copyright 2010. Published by Elsevier Inc.
Copyright 2010. Published by Elsevier Inc.
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Keywords Synthesis
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Gynecology
Follicle stimulating hormone
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References Liu, Hu, Zhou, Jiu, Yang, Wu, Xu (bib97) 2006; 207
Hashimoto, Nakamura, Shoji, Shimasaki, Hayashi, Sugino (bib32) 1997; 272
Dasen, O'Connell, Flynn, Treier, Gleiberman, Szeto (bib148) 1999; 97
Kumar, Low (bib240) 1995; 61
Huhtaniemi, Themmen (bib1) 2005; 26
Ying (bib24) 1988; 9
McArdle, Franklin, Green, Hislop (bib152) 2002; 173
Weiss, Harris, Halvorson, Crowley, Jameson (bib197) 1992; 131
Shupnik, Gharib, Chin (bib263) 1989; 3
Schneider, Burgess, Sleiter, DonCarlos, Lydon, O'Malley, Levine (bib191) 2005; 146
Safwat, Ninomiya-Tsuji, Gore, Miller (bib224) 2005; 146
Charlton, Halpin, Iddon, Rosie, Levy, McDowell (bib17) 1983; 113
Coss, Jacobs, Bender, Mellon (bib167) 2004; 279
Cushman, Burrows, Seasholtz, Lewandoski, Muzyczka, Camper (bib276) 2000; 28
Roseweir, Millar (bib65) 2009; 15
Winters (bib243) 1994; 15
Crawford, McNeilly, Nicol, McNeilly (bib79) 2002; 124
Lariviere, Garrel, Simon, Soh, Laverriere, Counis, Cohen-Tannoudji (bib182) 2007; 148
Uccella, La Rosa, Genasetti, Capella (bib49) 2000; 3
McConnell, Wang, Sluss, Bolf, Khoury, Schneyer (bib45) 1998; 83
Kumar, Schuff, Nusser, Low (bib229) 2006; 247
Sheng, Zhadanov, Mosinger, Fujii, Bertuzzi, Grinberg (bib146) 1996; 272
Sloop, Meier, Bridwell, Parker, Schiller, Rhodes (bib147) 1999; 13
Haisenleder, Ortolano, Dalkin, Ellis, Paul, Marshall (bib161) 1990; 127
Cattanach, Iddon, Charlton, Chiappa, Fink (bib15) 1977; 269
Alarid, Windle, Whyte, Mellon (bib113) 1996; 122
Feng, Lawson, Melamed (bib211) 2008; 79
Dobkin-Bekman, Naidich, Pawson, Millar, Seger, Naor (bib154) 2006; 252
Nicol, Faure, McNeilly, Fontaine, Taragnat, McNeilly (bib75) 2008; 196
Berger, Souza, Brito, d'Alva, Mendonca, Latronico (bib10) 2005; 83
Dalkin, Haisenleder, Ortolano, Ellis, Marshall (bib160) 1989; 125
Thackray, McGillivray, Mellon (bib188) 2006; 20
Halvorson, Ito, Jameson, Chin (bib125) 1998; 273
Haisenleder, Burger, Aylor, Dalkin, Walsh, Shupnik, Marshall (bib233) 2005; 72
Reame, Wyman, Phillips, de Kretser, Padmanabhan (bib54) 1998; 83
McLachlan, Dahl, Bremner, Schwall, Schmelzer, Mason, Steiner (bib58) 1989; 125
Coss, Thackray, Deng, Mellon (bib216) 2005; 19
Melamed, Kadir, Wijeweera, Seah (bib267) 2006; 252
Phillip, Arbelle, Segev, Parvari (bib9) 1998; 338
Tse, Tse, Almers, Hille (bib91) 1993; 260
Bouligand, Ghervan, Tello, Brailly-Tabard, Salenave, Chanson (bib16) 2009; 360
Hirota, Hirota, Aguilera, Catt (bib96) 1986; 249
Chen, An, Cheng, Hammond, Leung (bib177) 2009
Naor, Azrad, Limor, Zakut, Lotan (bib84) 1986; 261
Suszko, Lo, Suh, Camper, Woodruff (bib138) 2003; 17
Stouffer, Woodruff, Dahl, Hess, Mather, Molskness (bib60) 1993; 77
Kumar, Low, Matzuk (bib228) 1998; 139
Zhao, Bakke, Krimkevich, Cushman, Parlow, Camper, Parker (bib122) 2001; 128
Burger, Haisenleder, Aylor, Marshall (bib164) 2008; 79
Lee, Khivansara, Santos, Lamba, Yuen, Sealfon, Bernard (bib40) 2007; 38
Miller, Wu (bib259) 1981; 108
Gieske, Kim, Legan, Koo, Krust, Chambon, Ko (bib67) 2008; 149
Lamba, Khivansara, D'Alessio, Santos, Bernard (bib136) 2008; 149
Graham, Nusser, Low (bib114) 1999; 162
Hall, Schoenfeld, Martin, Crowley (bib268) 1992; 74
Dierich, Sairam, Monaco, Fimia, Gansmuller, LeMeur, Sassone-Corsi (bib6) 1998; 95
Spady, Shayya, Thackray, Ehrensberger, Bailey, Mellon (bib236) 2004; 18
Kumar, Agno, Janovick, Conn, Matzuk (bib44) 2003; 212
Izumi, Stojilkovic, Iida, Krsmanovic, Omeljaniuk, Catt (bib93) 1990; 170
Lamba, Santos, Philips, Bernard (bib207) 2006; 36
Finkelstein, Whitcomb, O'Dea, Longcope, Schoenfeld, Crowley (bib241) 1991; 73
Pernasetti, Spady, Hall, Rosenberg, Givens, Anderson (bib273) 2003; 203
Schwall, Nikolics, Szonyi, Gorman, Mason (bib35) 1988; 2
McNeilly, Crawford, Taragnat, Nicol, McNeilly (bib101) 2003; 61
Matzuk, Kumar, Shou, Coerver, Lau, Behringer, Finegold (bib34) 1996; 51
Roberts, Meunier, Vaughan, Rivier, Rivier, Vale, Sawchenko (bib39) 1989; 124
Gregory, Lacza, Detz, Xu, Petrillo, Kaiser (bib168) 2005; 19
Sheckter, Matsumoto, Bremner (bib242) 1989; 68
Wu, Su, Safwat, Sebastian, Miller (bib107) 2004; 145
Crawford, McNeilly (bib78) 2002; 174
Vassalli, Matzuk, Gardner, Lee, Jaenisch (bib42) 1994; 8
Lau, Kumar, Nishimori, Bonadio, Matzuk (bib33) 2000; 20
Borgstein, Yang, Condon, Haltom, Sherman (bib56) 2009; 69
Vasilyev, Pernasetti, Rosenberg, Barsoum, Austin, Webster, Mellon (bib169) 2002; 143
Ying, Becker, Swanson, Tan, Ling, Esch (bib29) 1987; 149
Moore, Villafuerte, Unick, Winters (bib70) 2009; 150
Vale, Rivier, Hsueh, Campen, Meunier, Bicsak (bib23) 1988; 44
Jablonka-Shariff, Pearl, Comstock, Boime (bib103) 2008; 283
Ferris, Shupnik (bib18) 2006; 74
Duan, Shin, Jameson (bib186) 1999; 13
Knox, Schwartz (bib247) 1992; 46
Klein, Illingworth, Groome, McNeilly, Battaglia, Soules (bib55) 1996; 81
Besecke, Guendner, Schneyer, Bauer-Dantoin, Jameson, Weiss (bib231) 1996; 137
Markkula, Hamalainen, Zhang, Kim, Maurer, Huhtaniemi (bib275) 1993; 96
Burger, Haisenleder, Wotton, Aylor, Dalkin, Marshall (bib239) 2007; 293
Tremblay, Goodyer, Drouin (bib129) 2000; 71
Zakaria, Jeong, Lacza, Kaiser (bib139) 2002; 16
Strahl, Huang, Sebastian, Ghosh, Miller (bib175) 1998; 139
Fingscheidt, Weinbauer, Fehm, Nieschlag (bib246) 1998; 159
Takano, Yamashita, Kojima, Kitaoka, Teramoto, Ogata (bib51) 1992; 182
Moumne, Batista, Benayoun, Nallathambi, Fellous, Sundaresan, Veitia (bib218) 2008; 282
Dalkin, Burger, Aylor, Haisenleder, Workman, Cho, Marshall (bib185) 2001; 142
Farnworth (bib100) 1995; 145
Mody, Leitch, Armstrong, Dixon, Cohen (bib173) 2001; 502
Huang, Sebastian, Strahl, Wu, Miller (bib180) 2001; 142
Hayes, Zarnegar, Sharma, Yang, Peehl, ten Dijke, Sun (bib237) 2001; 61
Dupont, McNeilly, Vaiman, Canepa, Combarnous, Taragnat (bib199) 2003; 68
Hewitt, Harrell, Korach (bib265) 2005; 67
Lindstedt, Nystrom, Matthews, Ernest, Janson, Chatterjee (bib11) 1998; 36
Kiesel, Bertges, Rabe, Runnebaum (bib82) 1986; 134
Han, Miller (bib140) 2009; 7
Albanese, Colin, Crowley, Ito, Pestell, Weiss, Jameson (bib105) 1996; 51
McGillivray, Thackray, Coss, Mellon (bib206) 2007; 148
Danilovich, Babu, Xing, Gerdes, Krishnamurthy, Sairam (bib5) 2000; 141
MacNaughton, Banah, McCloud, Hee, Burger (bib53) 1992; 36
Fortin, Lamba, Wang, Bernard (bib121) 2009; 15
Naor (bib153) 2009; 30
Pernasetti, Vasilyev, Rosenberg, Bailey, Huang, Miller, Mellon (bib41) 2001; 142
Smith (bib66) 2009; 30
Huang, Sebastian, Strahl, Wu, Miller (bib179) 2001; 142
Ciccone, Lacza, Hou, Gregory, Kam, Xu, Kaiser (bib181) 2008; 22
Schwartz, Rivier, Rivier, Vale (bib269) 1985; 32
Attardi, Winters (bib210) 1993; 7
Carroll, Corrigan, Gharib, Vale, Chin (bib196) 1989; 3
Maurer, Kim, Schoderbek, Roberson, Glenn (bib106) 1999; 54
Winters, Moore (bib69) 2007; 25
Jornvall, Reissmann, Andersson, Mehrkash, Ibanez (bib204) 2004; 24
De Baere, Copelli, Caburet, Laissue, Beysen, Christin-Maitre (bib219) 2005; 2
Laping, Grygielko, Mathur, Butter, Bomberger, Tweed (bib226) 2002; 62
Batra, Miller (bib238) 1985; 117
Coss, Hand, Yaphockun, Ely, Mellon (bib166) 2007; 21
Lanctot, Lamolet, Drouin (bib144) 1997; 124
Lee, Wesselschmidt, Linette, Kanagawa, Russell, Milbrandt (bib193) 1995; 269
McArdle, Poch (bib86) 1992; 130
Woodruff, D'Agostino, Schwartz, Mayo (bib272) 1988; 239
Huang, Wu, Su, Zhirnov, Miller (bib74) 2001; 142
Bliss, Miller, Navratil, Xie, McDonough, Fisher (bib171) 2009; 23
Zhang, Bailey, Coss, Lin, Tsutsumi, Lawson (bib225) 2006; 20
Beato, Herrlich, Schutz (bib251) 1995; 83
Welt, Hall, Adams, Taylor (bib57) 2005; 90
Kumar, Wang, Lu, Matzuk (bib4) 1997; 15
Carroll, Corrigan, Vale, Chin (bib209) 1991; 129
Lamba, Fortin, Tran, Wang, Bernard (bib212) 2009; 23
Ikeda, Luo, Abbud, Nilson, Parker (bib123) 1995; 9
Matzuk, Kumar, Bradley (bib43) 1995; 374
Tremblay, Drouin (bib128) 1999; 19
Paul, Ortolano, Haisenleder, Stewart, Shupnik, Marshall (bib232) 1990; 4
Moore, Winters (bib71) 2008; 78
Bohnsack, Szabo, Kilen, Tam, Schwartz (bib253) 2000; 62
Miyake, Irahara, Shitukawa, Yasui, Aono (bib255) 1993; 194
Nicol, McNeilly, Stridsberg, McNeilly (bib102) 2004; 32
Blount, Schmidt, Justice, Vale, Fischer, Bilezikjian (bib222) 2009; 284
Naor, Zer, Zakut, Hermon (bib99) 1985; 82
Shi, Wang, Jayaraman, Yang, Massague, Pavletich (bib215) 1998; 94
Otsuka, Shimasaki (bib76) 2002; 143
Woodruff, D'Agostino, Schwartz, Mayo (bib271) 1989; 124
Thompson, Lerch, Cook, Woodruff, Jardetzky (bib30) 2005; 9
Muttukrishna, Fowler, George, Groome, Knight (bib46) 1996; 81
Winters, Moore (bib245) 2004; 128
Faure, Nicol, Fabre, Fontaine, Mohoric, McNeilly, Taragnat (bib72) 2005; 186
Bilezikjian, Blount, Leal, Donaldson, Fischer, Vale (bib25) 2004; 225
Suszko, Balkin, Chen, Woodruff (bib205) 2005; 19
Gordon, Lewis, Haugen, James, McDermott, Wood, Ridgway (bib116) 1997; 272
Kaiser (bib159) 1998; 8
Belchetz, Plant, Nakai, Keogh, Knobil (bib21) 1978; 202
Thackray, Mellon (bib189) 2008; 149
Naik, Pittman, Wolfe, Miller, Radovick, Wondisford (bib151) 2006; 37
Besecke, Guendner, Sluss, Polak, Woodruff, Jameson, Bauer-Dantoin, Weiss (bib47) 1997; 138
Kamakura, Moriguchi, Nishida (bib172) 1999; 274
Attardi, Miklos (bib195) 1990; 4
Tse, Hille (bib90) 1992; 255
Uhlenhaut, Treier (bib217) 2006; 88
Szabo, Kilen, Saberi, Ringstrom, Schwartz (bib256) 1998; 139
Ringstrom, Szabo, Kilen, Saberi, Knox, Schwartz (bib249) 1997; 138
Giltay, Deege, Blankenstein, Kastrop, Wijmenga, Lock (bib13) 2004; 81
Layman, Porto, Xie, da Motta, da Motta, Weiser, Sluss (bib8) 2002; 87
Knox, Ringstrom, Schwartz (bib250) 1993; 133
Glidewell-Kenney, Weiss, Hurley, Levine, Jameson (bib262) 2008; 149
Dorn, Ou, Svaren, Crawford, Sadovsky (bib124) 1999; 274
Baron, Batista, Chaffaux, Cocquet, Cotinot, Cribiu (bib220) 2005; 45
West, Parker, Savage, Kiratipranon, Toomey, Beach (bib132) 2004; 145
Mantovani, Borgato, Beck-Peccoz, Romoli, Borretta, Persani (bib12) 2003; 79
Bernard (bib111) 2004; 18
Bailey, Rave-Harel, McGillivray, Coss, Mellon (bib208) 2004; 18
Blumenfeld, Ritter (bib52) 2001; 943
Quentien, Pitoia, Gunz, Guillet, Enjalbert, Pellegrini (bib119) 2002; 143
Naor, Dan-Cohen, Hermon, Limor (bib98) 1989; 86
Lewis, Gray, Blount, MacConell, Wiater, Bilezikjian, Vale (bib27) 2000; 404
Liu, Usui, Evans, Austin, Mellon, Olefsky, Webster (bib183) 2002; 277
Iida, Stojilkovic, Izumi, Catt (bib85) 1991; 5
Charles,
Welt (10.1016/j.fertnstert.2010.03.034_bib36) 1998; 139
McLachlan (10.1016/j.fertnstert.2010.03.034_bib58) 1989; 125
Duan (10.1016/j.fertnstert.2010.03.034_bib186) 1999; 13
Halvorson (10.1016/j.fertnstert.2010.03.034_bib125) 1998; 273
Paul (10.1016/j.fertnstert.2010.03.034_bib232) 1990; 4
Roa (10.1016/j.fertnstert.2010.03.034_bib64) 2009; 30
McArdle (10.1016/j.fertnstert.2010.03.034_bib86) 1992; 130
Ingraham (10.1016/j.fertnstert.2010.03.034_bib120) 1994; 8
Japon (10.1016/j.fertnstert.2010.03.034_bib110) 1994; 42
McArdle (10.1016/j.fertnstert.2010.03.034_bib152) 2002; 173
Winters (10.1016/j.fertnstert.2010.03.034_bib245) 2004; 128
Ortolano (10.1016/j.fertnstert.2010.03.034_bib270) 1988; 123
Attardi (10.1016/j.fertnstert.2010.03.034_bib210) 1993; 7
Kumar (10.1016/j.fertnstert.2010.03.034_bib4) 1997; 15
Jorgensen (10.1016/j.fertnstert.2010.03.034_bib104) 2004; 25
Weiss (10.1016/j.fertnstert.2010.03.034_bib112) 1995; 136
Lanctot (10.1016/j.fertnstert.2010.03.034_bib144) 1997; 124
Steger (10.1016/j.fertnstert.2010.03.034_bib149) 1994; 14
Ruf (10.1016/j.fertnstert.2010.03.034_bib155) 2004; 15
Thompson (10.1016/j.fertnstert.2010.03.034_bib30) 2005; 9
Besecke (10.1016/j.fertnstert.2010.03.034_bib47) 1997; 138
Marshall (10.1016/j.fertnstert.2010.03.034_bib19) 1993; 104
Esch (10.1016/j.fertnstert.2010.03.034_bib28) 1987; 1
Lahlou (10.1016/j.fertnstert.2010.03.034_bib48) 1999; 14
Borgstein (10.1016/j.fertnstert.2010.03.034_bib56) 2009; 69
Stouffer (10.1016/j.fertnstert.2010.03.034_bib59) 1994; 50
Nicol (10.1016/j.fertnstert.2010.03.034_bib102) 2004; 32
Kumar (10.1016/j.fertnstert.2010.03.034_bib228) 1998; 139
Otsuka (10.1016/j.fertnstert.2010.03.034_bib76) 2002; 143
Dupont (10.1016/j.fertnstert.2010.03.034_bib199) 2003; 68
Tapanainen (10.1016/j.fertnstert.2010.03.034_bib7) 1997; 15
Mason (10.1016/j.fertnstert.2010.03.034_bib14) 1986; 234
Shupnik (10.1016/j.fertnstert.2010.03.034_bib263) 1989; 3
Crawford (10.1016/j.fertnstert.2010.03.034_bib79) 2002; 124
Hirota (10.1016/j.fertnstert.2010.03.034_bib96) 1986; 249
Halvorson (10.1016/j.fertnstert.2010.03.034_bib126) 1996; 271
Stouffer (10.1016/j.fertnstert.2010.03.034_bib60) 1993; 77
Coss (10.1016/j.fertnstert.2010.03.034_bib166) 2007; 21
Albanese (10.1016/j.fertnstert.2010.03.034_bib105) 1996; 51
Turgeon (10.1016/j.fertnstert.2010.03.034_bib190) 2006; 190
Suh (10.1016/j.fertnstert.2010.03.034_bib142) 2002; 129
Tse (10.1016/j.fertnstert.2010.03.034_bib90) 1992; 255
Burger (10.1016/j.fertnstert.2010.03.034_bib156) 2004; 33
Albarracin (10.1016/j.fertnstert.2010.03.034_bib274) 1999; 140
Huang (10.1016/j.fertnstert.2010.03.034_bib74) 2001; 142
Knox (10.1016/j.fertnstert.2010.03.034_bib250) 1993; 133
Ferris (10.1016/j.fertnstert.2010.03.034_bib18) 2006; 74
Strahl (10.1016/j.fertnstert.2010.03.034_bib175) 1998; 139
Fingscheidt (10.1016/j.fertnstert.2010.03.034_bib246) 1998; 159
Batra (10.1016/j.fertnstert.2010.03.034_bib238) 1985; 117
Lamba (10.1016/j.fertnstert.2010.03.034_bib136) 2008; 149
Jablonka-Shariff (10.1016/j.fertnstert.2010.03.034_bib103) 2008; 283
Attardi (10.1016/j.fertnstert.2010.03.034_bib195) 1990; 4
Markkula (10.1016/j.fertnstert.2010.03.034_bib275) 1993; 96
Zhao (10.1016/j.fertnstert.2010.03.034_bib122) 2001; 128
Takano (10.1016/j.fertnstert.2010.03.034_bib51) 1992; 182
Safwat (10.1016/j.fertnstert.2010.03.034_bib224) 2005; 146
Tremblay (10.1016/j.fertnstert.2010.03.034_bib129) 2000; 71
Suszko (10.1016/j.fertnstert.2010.03.034_bib137) 2008; 281
Stojilkovic (10.1016/j.fertnstert.2010.03.034_bib88) 1990; 2
Zawel (10.1016/j.fertnstert.2010.03.034_bib213) 1998; 1
Graham (10.1016/j.fertnstert.2010.03.034_bib114) 1999; 162
Suszko (10.1016/j.fertnstert.2010.03.034_bib200) 2006; 36
Knox (10.1016/j.fertnstert.2010.03.034_bib247) 1992; 46
Lindstedt (10.1016/j.fertnstert.2010.03.034_bib11) 1998; 36
Schwartz (10.1016/j.fertnstert.2010.03.034_bib269) 1985; 32
Smith (10.1016/j.fertnstert.2010.03.034_bib66) 2009; 30
Su (10.1016/j.fertnstert.2010.03.034_bib214) 2007; 148
Hall (10.1016/j.fertnstert.2010.03.034_bib268) 1992; 74
Kaiser (10.1016/j.fertnstert.2010.03.034_bib127) 2000; 14
Schwall (10.1016/j.fertnstert.2010.03.034_bib35) 1988; 2
Southworth (10.1016/j.fertnstert.2010.03.034_bib22) 1991; 72
Vassalli (10.1016/j.fertnstert.2010.03.034_bib42) 1994; 8
Dorn (10.1016/j.fertnstert.2010.03.034_bib124) 1999; 274
Ellsworth (10.1016/j.fertnstert.2010.03.034_bib221) 2003; 206
Berger (10.1016/j.fertnstert.2010.03.034_bib10) 2005; 83
Moumne (10.1016/j.fertnstert.2010.03.034_bib218) 2008; 282
Blount (10.1016/j.fertnstert.2010.03.034_bib222) 2009; 284
Morgan (10.1016/j.fertnstert.2010.03.034_bib83) 1987; 262
Corrigan (10.1016/j.fertnstert.2010.03.034_bib38) 1991; 128
Klein (10.1016/j.fertnstert.2010.03.034_bib55) 1996; 81
An (10.1016/j.fertnstert.2010.03.034_bib187) 2009; 81
Burger (10.1016/j.fertnstert.2010.03.034_bib164) 2008; 79
Cash (10.1016/j.fertnstert.2010.03.034_bib31) 2009; 28
Tremblay (10.1016/j.fertnstert.2010.03.034_bib131) 1998; 12
Moore (10.1016/j.fertnstert.2010.03.034_bib70) 2009; 150
Ho (10.1016/j.fertnstert.2010.03.034_bib73) 2009; 81
Haisenleder (10.1016/j.fertnstert.2010.03.034_bib174) 2008; 149
Baratta (10.1016/j.fertnstert.2010.03.034_bib37) 2001; 64
Phillip (10.1016/j.fertnstert.2010.03.034_bib9) 1998; 338
Lariviere (10.1016/j.fertnstert.2010.03.034_bib182) 2007; 148
Li (10.1016/j.fertnstert.2010.03.034_bib257) 2003; 278
Ikeda (10.1016/j.fertnstert.2010.03.034_bib123) 1995; 9
Naor (10.1016/j.fertnstert.2010.03.034_bib98) 1989; 86
Dalkin (10.1016/j.fertnstert.2010.03.034_bib185) 2001; 142
Zakaria (10.1016/j.fertnstert.2010.03.034_bib139) 2002; 16
Schneider (10.1016/j.fertnstert.2010.03.034_bib191) 2005; 146
Kumar (10.1016/j.fertnstert.2010.03.034_bib229) 2006; 247
Ciccone (10.1016/j.fertnstert.2010.03.034_bib181) 2008; 22
Maurer (10.1016/j.fertnstert.2010.03.034_bib106) 1999; 54
Singh (10.1016/j.fertnstert.2010.03.034_bib68) 2009; 81
Hewitt (10.1016/j.fertnstert.2010.03.034_bib265) 2005; 67
Grigorova (10.1016/j.fertnstert.2010.03.034_bib277) 2008; 23
Coss (10.1016/j.fertnstert.2010.03.034_bib216) 2005; 19
Kumar (10.1016/j.fertnstert.2010.03.034_bib240) 1995; 61
Gordon (10.1016/j.fertnstert.2010.03.034_bib116) 1997; 272
Gray (10.1016/j.fertnstert.2010.03.034_bib26) 2002; 188
Cattanach (10.1016/j.fertnstert.2010.03.034_bib15) 1977; 269
Lanctot (10.1016/j.fertnstert.2010.03.034_bib135) 1999; 140
Thackray (10.1016/j.fertnstert.2010.03.034_bib189) 2008; 149
Naik (10.1016/j.fertnstert.2010.03.034_bib151) 2006; 37
Mody (10.1016/j.fertnstert.2010.03.034_bib173) 2001; 502
Roseweir (10.1016/j.fertnstert.2010.03.034_bib65) 2009; 15
Kalkhoven (10.1016/j.fertnstert.2010.03.034_bib184) 2004; 68
Thackray (10.1016/j.fertnstert.2010.03.034_bib188) 2006; 20
Finkelstein (10.1016/j.fertnstert.2010.03.034_bib241) 1991; 73
Wu (10.1016/j.fertnstert.2010.03.034_bib107) 2004; 145
Blumenfeld (10.1016/j.fertnstert.2010.03.034_bib52) 2001; 943
Muttukrishna (10.1016/j.fertnstert.2010.03.034_bib46) 1996; 81
Kanasaki (10.1016/j.fertnstert.2010.03.034_bib158) 2005; 146
Shi (10.1016/j.fertnstert.2010.03.034_bib215) 1998; 94
Quentien (10.1016/j.fertnstert.2010.03.034_bib118) 2002; 277
Haisenleder (10.1016/j.fertnstert.2010.03.034_bib161) 1990; 127
Spady (10.1016/j.fertnstert.2010.03.034_bib236) 2004; 18
McConnell (10.1016/j.fertnstert.2010.03.034_bib45) 1998; 83
Themmen (10.1016/j.fertnstert.2010.03.034_bib2) 2000; 21
Tse (10.1016/j.fertnstert.2010.03.034_bib92) 1997; 18
Naor (10.1016/j.fertnstert.2010.03.034_bib153) 2009; 30
Zhang (10.1016/j.fertnstert.2010.03.034_bib225) 2006; 20
Kiesel (10.1016/j.fertnstert.2010.03.034_bib82) 1986; 134
Dalkin (10.1016/j.fertnstert.2010.03.034_bib160) 1989; 125
Pangas (10.1016/j.fertnstert.2010.03.034_bib198) 2000; 11
Tasaka (10.1016/j.fertnstert.2010.03.034_bib89) 1988; 154
Vasilyev (10.1016/j.fertnstert.2010.03.034_bib169) 2002; 143
Miyake (10.1016/j.fertnstert.2010.03.034_bib255) 1993; 194
Webster (10.1016/j.fertnstert.2010.03.034_bib235) 1995; 136
Welt (10.1016/j.fertnstert.2010.03.034_bib57) 2005; 90
Charles (10.1016/j.fertnstert.2010.03.034_bib141) 2008; 46
Lamba (10.1016/j.fertnstert.2010.03.034_bib212) 2009; 23
Watanabe (10.1016/j.fertnstert.2010.03.034_bib80) 1991; 96
Melamed (10.1016/j.fertnstert.2010.03.034_bib267) 2006; 252
Naor (10.1016/j.fertnstert.2010.03.034_bib84) 1986; 261
Gieske (10.1016/j.fertnstert.2010.03.034_bib67) 2008; 149
Charles (10.1016/j.fertnstert.2010.03.034_bib150) 2006; 20
Naor (10.1016/j.fertnstert.2010.03.034_bib87) 1988; 2
Szabo (10.1016/j.fertnstert.2010.03.034_bib256) 1998; 139
Andrews (10.1016/j.fertnstert.2010.03.034_bib81) 1986; 118
Haisenleder (10.1016/j.fertnstert.2010.03.034_bib162) 1991; 128
Crawford (10.1016/j.fertnstert.2010.03.034_bib78) 2002; 174
Pernasetti (10.1016/j.fertnstert.2010.03.034_bib41) 2001; 142
Danilovich (10.1016/j.fertnstert.2010.03.034_bib5) 2000; 141
Leal (10.1016/j.fertnstert.2010.03.034_bib254) 2003; 77
Hayes (10.1016/j.fertnstert.2010.03.034_bib237) 2001; 61
Haisenleder (10.1016/j.fertnstert.2010.03.034_bib233) 2005; 72
West (10.1016/j.fertnstert.2010.03.034_bib132) 2004; 145
Han (10.1016/j.fertnstert.2010.03.034_bib140) 2009; 7
Tse (10.1016/j.fertnstert.2010.03.034_bib91) 1993; 260
Suszko (10.1016/j.fertnstert.2010.03.034_bib138) 2003; 17
Iida (10.1016/j.fertnstert.2010.03.034_bib85) 1991; 5
Charlton (10.1016/j.fertnstert.2010.03.034_bib17) 1983; 113
Gu (10.1016/j.fertnstert.2010.03.034_bib203) 1998; 12
Faure (10.1016/j.fertnstert.2010.03.034_bib72) 2005; 186
Carroll (10.1016/j.fertnstert.2010.03.034_bib196) 1989; 3
Lawson (10.1016/j.fertnstert.2010.03.034_bib234) 2001; 170
Lau (10.1016/j.fertnstert.2010.03.034_bib33) 2000; 20
De Baere (10.1016/j.fertnstert.2010.03.034_bib219) 2005; 2
Dierich (10.1016/j.fertnstert.2010.03.034_bib6) 1998; 95
Haisenleder (10.1016/j.fertnstert.2010.03.034_bib163) 1998; 139
Mantovani (10.1016/j.fertnstert.2010.03.034_bib12) 2003; 79
Lawson (10.1016/j.fertnstert.2010.03.034_bib194) 2007; 21
Windle (10.1016/j.fertnstert.2010.03.034_bib109) 1990; 4
Woodruff (10.1016/j.fertnstert.2010.03.034_bib272) 1988; 239
Bilezikjian (10.1016/j.fertnstert.2010.03.034_bib25) 2004; 225
Bohnsack (10.1016/j.fertnstert.2010.03.034_bib253) 2000; 62
Matzuk (
References_xml – volume: 50
  start-page: 888
  year: 1994
  end-page: 895
  ident: bib59
  article-title: Systemic and intraluteal infusion of inhibin A or activin A in rhesus monkeys during the luteal phase of the menstrual cycle
  publication-title: Biol Reprod
– volume: 138
  start-page: 2841
  year: 1997
  end-page: 2848
  ident: bib47
  article-title: Pituitary follistatin regulates activin-mediated production of follicle-stimulating hormone during the rat estrous cycle
  publication-title: Endocrinology
– volume: 3
  start-page: 1969
  year: 1989
  end-page: 1976
  ident: bib196
  article-title: Inhibin, activin, and follistatin: regulation of follicle-stimulating hormone messenger ribonucleic acid levels
  publication-title: Mol Endocrinol
– volume: 282
  start-page: 2
  year: 2008
  end-page: 11
  ident: bib218
  article-title: The mutations and potential targets of the forkhead transcription factor FOXL2
  publication-title: Mol Cell Endocrinol
– volume: 142
  start-page: 2260
  year: 2001
  end-page: 2266
  ident: bib179
  article-title: The promoter for the ovine follicle-stimulating hormone–β gene (FSHβ) confers FSHβ-like expression on luciferase in transgenic mice: regulatory studies in vivo and in vitro
  publication-title: Endocrinology
– volume: 274
  start-page: 26563
  year: 1999
  end-page: 26571
  ident: bib172
  article-title: Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus
  publication-title: J Biol Chem
– volume: 130
  start-page: 3567
  year: 1992
  end-page: 3574
  ident: bib86
  article-title: Dependence of gonadotropin-releasing hormone-stimulated luteinizing hormone release upon intracellular Ca
  publication-title: Endocrinology
– volume: 67
  start-page: 285
  year: 2005
  end-page: 308
  ident: bib265
  article-title: Lessons in estrogen biology from knockout and transgenic animals
  publication-title: Annu Rev Physiol
– volume: 122
  start-page: 3319
  year: 1996
  end-page: 3329
  ident: bib113
  article-title: Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice
  publication-title: Development
– volume: 149
  start-page: 3095
  year: 2008
  end-page: 3108
  ident: bib136
  article-title: Paired-like homeodomain transcription factors 1 and 2 regulate follicle-stimulating hormone β-subunit transcription through a conserved
  publication-title: Endocrinology
– volume: 28
  start-page: 167
  year: 2000
  end-page: 174
  ident: bib276
  article-title: Cre-mediated recombination in the pituitary gland
  publication-title: Genesis
– volume: 269
  start-page: 532
  year: 1995
  end-page: 535
  ident: bib193
  article-title: Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)
  publication-title: Science
– volume: 79
  start-page: 546
  year: 2008
  end-page: 561
  ident: bib211
  article-title: A proteomic comparison of immature and mature mouse gonadotrophs reveals novel differentially expressed nuclear proteins that regulate gonadotropin gene transcription and RNA splicing
  publication-title: Biol Reprod
– volume: 141
  start-page: 4295
  year: 2000
  end-page: 4308
  ident: bib5
  article-title: Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mice
  publication-title: Endocrinology
– volume: 174
  start-page: 179
  year: 2002
  end-page: 194
  ident: bib78
  article-title: Co-localisation of gonadotrophins and granins in gonadotrophs at different stages of the oestrous cycle in sheep
  publication-title: J Endocrinol
– volume: 15
  start-page: 216
  year: 1994
  end-page: 219
  ident: bib243
  article-title: FSH is produced by GnRH-deficient men and is suppressed by testosterone
  publication-title: J Androl
– volume: 283
  start-page: 11485
  year: 2008
  end-page: 11492
  ident: bib103
  article-title: A carboxyl-terminal sequence in the lutropin β subunit contributes to the sorting of lutropin to the regulated pathway
  publication-title: J Biol Chem
– volume: 36
  start-page: 339
  year: 1992
  end-page: 345
  ident: bib53
  article-title: Age related changes in follicle stimulating hormone, luteinizing hormone, oestradiol and immunoreactive inhibin in women of reproductive age
  publication-title: Clin Endocrinol (Oxf)
– volume: 73
  start-page: 609
  year: 1991
  end-page: 620
  ident: bib241
  article-title: Sex steroid control of gonadotropin secretion in the human male. I. Effects of testosterone administration in normal and gonadotropin-releasing hormone–deficient men
  publication-title: J Clin Endocrinol Metab
– volume: 943
  start-page: 34
  year: 2001
  end-page: 48
  ident: bib52
  article-title: Inhibin, activin, and follistatin in human fetal pituitary and gonadal physiology
  publication-title: Ann N Y Acad Sci
– volume: 273
  start-page: 16
  year: 2007
  end-page: 24
  ident: bib266
  article-title: Estrogen receptor signaling is an unstable feature of the gonadotropic LβT2 cell line
  publication-title: Mol Cell Endocrinol
– volume: 138
  start-page: 2621
  year: 1997
  end-page: 2631
  ident: bib176
  article-title: Two proximal activating protein-1–binding sites are sufficient to stimulate transcription of the ovine follicle-stimulating hormone–β gene
  publication-title: Endocrinology
– volume: 19
  start-page: 2610
  year: 2005
  end-page: 2623
  ident: bib216
  article-title: Activin regulates luteinizing hormone β-subunit gene expression through Smad-binding and homeobox elements
  publication-title: Mol Endocrinol
– volume: 138
  start-page: 2286
  year: 1997
  end-page: 2290
  ident: bib249
  article-title: The antiprogestins RU486 and ZK98299 affect follicle-stimulating hormone secretion differentially on estrus, but not on proestrus
  publication-title: Endocrinology
– volume: 143
  start-page: 4938
  year: 2002
  end-page: 4941
  ident: bib76
  article-title: A novel function of bone morphogenetic protein-15 in the pituitary: selective synthesis and secretion of FSH by gonadotropes
  publication-title: Endocrinology
– volume: 61
  start-page: 2112
  year: 2001
  end-page: 2118
  ident: bib237
  article-title: SMAD3 represses androgen receptor–mediated transcription
  publication-title: Cancer Res
– volume: 272
  start-page: 13835
  year: 1997
  end-page: 13842
  ident: bib32
  article-title: A novel role of follistatin, an activin-binding protein, in the inhibition of activin action in rat pituitary cells. Endocytotic degradation of activin and its acceleration by follistatin associated with cell-surface heparan sulfate
  publication-title: J Biol Chem
– volume: 13
  start-page: 2212
  year: 1999
  end-page: 2225
  ident: bib147
  article-title: Differential activation of pituitary hormone genes by human Lhx3 isoforms with distinct DNA binding properties
  publication-title: Mol Endocrinol
– volume: 170
  start-page: 359
  year: 1990
  end-page: 367
  ident: bib93
  article-title: Role of voltage-sensitive calcium channels in [Ca
  publication-title: Biochem Biophys Res Commun
– volume: 140
  start-page: 1416
  year: 1999
  end-page: 1422
  ident: bib135
  article-title: Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development
  publication-title: Endocrinology
– volume: 94
  start-page: 585
  year: 1998
  end-page: 594
  ident: bib215
  article-title: Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-β signaling
  publication-title: Cell
– volume: 133
  start-page: 277
  year: 1993
  end-page: 283
  ident: bib250
  article-title: RU486 blocks the effects of inhibin antiserum or luteinizing hormone on the secondary follicle-stimulating hormone surge
  publication-title: Endocrinology
– volume: 338
  start-page: 1729
  year: 1998
  end-page: 1732
  ident: bib9
  article-title: Male hypogonadism due to a mutation in the gene for the β-subunit of follicle-stimulating hormone
  publication-title: N Engl J Med
– volume: 278
  start-page: 41779
  year: 2003
  end-page: 41788
  ident: bib257
  article-title: Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-β action
  publication-title: J Biol Chem
– volume: 220
  start-page: 59
  year: 2004
  end-page: 65
  ident: bib201
  article-title: Activin isoforms signal through type I receptor serine/threonine kinase ALK7
  publication-title: Mol Cell Endocrinol
– volume: 293
  start-page: E277
  year: 2007
  end-page: E285
  ident: bib239
  article-title: The regulation of FSHβ transcription by gonadal steroids: testosterone and estradiol modulation of the activin intracellular signaling pathway
  publication-title: Am J Physiol Endocrinol Metab
– volume: 37
  start-page: 63
  year: 2006
  end-page: 69
  ident: bib151
  article-title: A novel technique for temporally regulated cell type-specific Cre expression and recombination in the pituitary gonadotroph
  publication-title: J Mol Endocrinol
– volume: 191
  start-page: 309
  year: 2006
  end-page: 317
  ident: bib264
  article-title: The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-alpha
  publication-title: J Endocrinol
– volume: 125
  start-page: 917
  year: 1989
  end-page: 924
  ident: bib160
  article-title: The frequency of gonadotropin-releasing-hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression
  publication-title: Endocrinology
– volume: 149
  start-page: 2701
  year: 2008
  end-page: 2711
  ident: bib108
  article-title: Functional characterization of genetically labeled gonadotropes
  publication-title: Endocrinology
– volume: 24
  start-page: 9383
  year: 2004
  end-page: 9389
  ident: bib204
  article-title: ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse
  publication-title: Mol Cell Biol
– volume: 2
  start-page: 512
  year: 1988
  end-page: 520
  ident: bib87
  article-title: Gonadotropin-releasing hormone-induced rise in cytosolic free Ca
  publication-title: Mol Endocrinol
– volume: 262
  start-page: 1166
  year: 1987
  end-page: 1171
  ident: bib83
  article-title: Novel aspects of gonadotropin-releasing hormone action on inositol polyphosphate metabolism in cultured pituitary gonadotrophs
  publication-title: J Biol Chem
– volume: 12
  start-page: 428
  year: 1998
  end-page: 441
  ident: bib131
  article-title: The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3
  publication-title: Mol Endocrinol
– volume: 72
  start-page: 523
  year: 2005
  end-page: 529
  ident: bib233
  article-title: Testosterone stimulates follicle-stimulating hormone β transcription via activation of extracellular signal-regulated kinase: evidence in rat pituitary cells
  publication-title: Biol Reprod
– volume: 188
  start-page: 254
  year: 2002
  end-page: 260
  ident: bib26
  article-title: Antagonism of activin by inhibin and inhibin receptors: a functional role for βglycan
  publication-title: Mol Cell Endocrinol
– volume: 23
  start-page: 2160
  year: 2008
  end-page: 2166
  ident: bib277
  article-title: FSHB promoter polymorphism within evolutionary conserved element is associated with serum FSH level in men
  publication-title: Hum Reprod
– volume: 71
  start-page: 277
  year: 2000
  end-page: 286
  ident: bib129
  article-title: Transcriptional properties of Ptx1 and Ptx2 isoforms
  publication-title: Neuroendocrinology
– volume: 127
  start-page: 2869
  year: 1990
  end-page: 2875
  ident: bib161
  article-title: Differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone pulse amplitude in female rats
  publication-title: Endocrinology
– volume: 64
  start-page: 714
  year: 2001
  end-page: 719
  ident: bib37
  article-title: Activin modulates differential effects of estradiol on synthesis and secretion of follicle-stimulating hormone in ovine pituitary cells
  publication-title: Biol Reprod
– volume: 272
  start-page: 1004
  year: 1996
  end-page: 1007
  ident: bib146
  article-title: Specification of pituitary cell lineages by the LIM homeobox gene Lhx3
  publication-title: Science
– volume: 77
  start-page: 298
  year: 2003
  end-page: 304
  ident: bib254
  article-title: Regulation of follicle-stimulating hormone secretion by the interactions of activin-A, dexamethasone and testosterone in anterior pituitary cell cultures of male rats
  publication-title: Neuroendocrinology
– volume: 46
  start-page: 507
  year: 2008
  end-page: 514
  ident: bib141
  article-title: Pitx2 deletion in pituitary gonadotropes is compatible with gonadal development, puberty, and fertility
  publication-title: Genesis
– volume: 502
  start-page: 21
  year: 2001
  end-page: 24
  ident: bib173
  article-title: Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway
  publication-title: FEBS Lett
– volume: 284
  start-page: 7631
  year: 2009
  end-page: 7645
  ident: bib222
  article-title: FoxL2 and Smad3 coordinately regulate follistatin gene transcription
  publication-title: J Biol Chem
– volume: 9
  start-page: 535
  year: 2005
  end-page: 543
  ident: bib30
  article-title: The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding
  publication-title: Dev Cell
– volume: 8
  start-page: 414
  year: 1994
  end-page: 427
  ident: bib42
  article-title: Activin/inhibin β B subunit gene disruption leads to defects in eyelid development and female reproduction
  publication-title: Genes Dev
– volume: 1
  start-page: 849
  year: 1987
  end-page: 855
  ident: bib28
  article-title: Structural characterization of follistatin: a novel follicle-stimulating hormone release-inhibiting polypeptide from the gonad
  publication-title: Mol Endocrinol
– volume: 142
  start-page: 2284
  year: 2001
  end-page: 2295
  ident: bib41
  article-title: Cell-specific transcriptional regulation of follicle-stimulating hormone-β by activin and gonadotropin-releasing hormone in the LβT2 pituitary gonadotrope cell model
  publication-title: Endocrinology
– volume: 131
  start-page: 1403
  year: 1992
  end-page: 1408
  ident: bib197
  article-title: Dynamic regulation of follicle-stimulating hormone-β messenger ribonucleic acid levels by activin and gonadotropin-releasing hormone in perifused rat pituitary cells
  publication-title: Endocrinology
– volume: 18
  start-page: 925
  year: 2004
  end-page: 940
  ident: bib236
  article-title: Androgen regulates follicle-stimulating hormone β gene expression in an activin-dependent manner in immortalized gonadotropes
  publication-title: Mol Endocrinol
– volume: 46
  start-page: 220
  year: 1992
  end-page: 225
  ident: bib247
  article-title: RU486 blocks the secondary surge of follicle-stimulating hormone in the rat without blocking the drop in serum inhibin
  publication-title: Biol Reprod
– volume: 12
  start-page: 844
  year: 1998
  end-page: 857
  ident: bib203
  article-title: The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse
  publication-title: Genes Dev
– volume: 148
  start-page: 4500
  year: 2007
  end-page: 4508
  ident: bib214
  article-title: Expression and regulation of the β-subunit of ovine follicle-stimulating hormone relies heavily on a promoter sequence likely to bind Smad-associated proteins
  publication-title: Endocrinology
– volume: 19
  start-page: 237
  year: 2005
  end-page: 254
  ident: bib168
  article-title: Synergy between activin A and gonadotropin-releasing hormone in transcriptional activation of the rat follicle-stimulating hormone–β gene
  publication-title: Mol Endocrinol
– volume: 19
  start-page: 1849
  year: 2005
  end-page: 1858
  ident: bib205
  article-title: Smad3 mediates activin-induced transcription of follicle-stimulating hormone β-subunit gene
  publication-title: Mol Endocrinol
– volume: 83
  start-page: 3302
  year: 1998
  end-page: 3307
  ident: bib54
  article-title: Net increase in stimulatory input resulting from a decrease in inhibin B and an increase in activin A may contribute in part to the rise in follicular phase follicle-stimulating hormone of aging cycling women
  publication-title: J Clin Endocrinol Metab
– volume: 239
  start-page: 1296
  year: 1988
  end-page: 1299
  ident: bib272
  article-title: Dynamic changes in inhibin messenger RNAs in rat ovarian follicles during the reproductive cycle
  publication-title: Science
– volume: 61
  start-page: 463
  year: 2003
  end-page: 476
  ident: bib101
  article-title: The differential secretion of FSH and LH: regulation through genes, feedback and packaging
  publication-title: Reprod Suppl
– volume: 21
  start-page: 1175
  year: 2007
  end-page: 1191
  ident: bib194
  article-title: Pulse sensitivity of the luteinizing hormone β promoter is determined by a negative feedback loop involving early growth response-1 and Ngfi-A binding protein 1 and 2
  publication-title: Mol Endocrinol
– volume: 28
  start-page: 2662
  year: 2009
  end-page: 2676
  ident: bib31
  article-title: The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
  publication-title: EMBO J
– volume: 4
  start-page: 597
  year: 1990
  end-page: 603
  ident: bib109
  article-title: Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice
  publication-title: Mol Endocrinol
– volume: 139
  start-page: 2223
  year: 1998
  end-page: 2228
  ident: bib256
  article-title: Antiprogestins suppress basal and activin-stimulated follicle-stimulating hormone secretion in an estrogen-dependent manner
  publication-title: Endocrinology
– volume: 26
  start-page: 207
  year: 2005
  end-page: 217
  ident: bib1
  article-title: Mutations in human gonadotropin and gonadotropin-receptor genes
  publication-title: Endocrine
– volume: 130
  start-page: 263
  year: 2005
  end-page: 274
  ident: bib3
  article-title: An update of the pathophysiology of human gonadotrophin subunit and receptor gene mutations and polymorphisms
  publication-title: Reproduction
– volume: 269
  start-page: 338
  year: 1977
  end-page: 340
  ident: bib15
  article-title: Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism
  publication-title: Nature
– volume: 87
  start-page: 3702
  year: 2002
  end-page: 3707
  ident: bib8
  article-title: FSH β gene mutations in a female with partial breast development and a male sibling with normal puberty and azoospermia
  publication-title: J Clin Endocrinol Metab
– volume: 25
  start-page: 379
  year: 2007
  end-page: 387
  ident: bib69
  article-title: Paracrine control of gonadotrophs
  publication-title: Semin Reprod Med
– volume: 128
  start-page: 1682
  year: 1991
  end-page: 1684
  ident: bib38
  article-title: Evidence for an autocrine role of activin B within rat anterior pituitary cultures
  publication-title: Endocrinology
– volume: 190
  start-page: 837
  year: 2006
  end-page: 846
  ident: bib190
  article-title: Differential expression and regulation of progesterone receptor isoforms in rat and mouse pituitary cells and LβT2 gonadotropes
  publication-title: J Endocrinol
– volume: 46
  start-page: 117
  year: 2008
  end-page: 143
  ident: bib62
  article-title: GPR54 and kisspeptins
  publication-title: Results Probl Cell Differ
– volume: 149
  start-page: 4168
  year: 2008
  end-page: 4176
  ident: bib262
  article-title: Estrogen receptor alpha signaling pathways differentially regulate gonadotropin subunit gene expression and serum follicle-stimulating hormone in the female mouse
  publication-title: Endocrinology
– volume: 51
  start-page: 123
  year: 1996
  end-page: 154
  ident: bib34
  article-title: Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development
  publication-title: Recent Prog Horm Res
– volume: 81
  start-page: 133
  year: 2009
  end-page: 141
  ident: bib73
  article-title: Bone morphogenetic protein 2 signals via BMPR1A to regulate murine follicle-stimulating hormone β subunit transcription
  publication-title: Biol Reprod
– volume: 68
  start-page: 397
  year: 1989
  end-page: 401
  ident: bib242
  article-title: Testosterone administration inhibits gonadotropin secretion by an effect directly on the human pituitary
  publication-title: J Clin Endocrinol Metab
– volume: 15
  start-page: 203
  year: 2009
  end-page: 212
  ident: bib65
  article-title: The role of kisspeptin in the control of gonadotrophin secretion
  publication-title: Hum Reprod Update
– volume: 78
  start-page: 752
  year: 2008
  end-page: 760
  ident: bib71
  article-title: Weaning and the developmental changes in follicle-stimulating hormone, pituitary adenylate cyclase-activating polypeptide, and inhibin B in the male rat
  publication-title: Biol Reprod
– volume: 14
  start-page: 1190
  year: 1999
  end-page: 1193
  ident: bib48
  article-title: Main inhibitor of follicle stimulating hormone in the luteal-follicular transition: inhibin A, oestradiol, or inhibin B?
  publication-title: Hum Reprod
– volume: 62
  start-page: 58
  year: 2002
  end-page: 64
  ident: bib226
  article-title: Inhibition of transforming growth factor (TGF)-β1–induced extracellular matrix with a novel inhibitor of the TGF-β type I receptor kinase activity: SB-431542
  publication-title: Mol Pharmacol
– volume: 139
  start-page: 469
  year: 1998
  end-page: 471
  ident: bib36
  article-title: Activin: an endocrine or paracrine agent?
  publication-title: Eur J Endocrinol
– volume: 9
  start-page: 267
  year: 1988
  end-page: 293
  ident: bib24
  article-title: Inhibins, activins, and follistatins: gonadal proteins modulating the secretion of follicle-stimulating hormone
  publication-title: Endocr Rev
– volume: 9
  start-page: 478
  year: 1995
  end-page: 486
  ident: bib123
  article-title: The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus
  publication-title: Mol Endocrinol
– volume: 146
  start-page: 5503
  year: 2005
  end-page: 5513
  ident: bib158
  article-title: Gonadotropin-releasing hormone pulse frequency–dependent activation of extracellular signal-regulated kinase pathways in perifused LβT2 cells
  publication-title: Endocrinology
– volume: 108
  start-page: 673
  year: 1981
  end-page: 679
  ident: bib259
  article-title: Estrogen regulation of follicle-stimulating hormone production in vitro: species variation
  publication-title: Endocrinology
– volume: 124
  start-page: 2193
  year: 1989
  end-page: 2199
  ident: bib271
  article-title: Decreased inhibin gene expression in preovulatory follicles requires primary gonadotropin surges
  publication-title: Endocrinology
– volume: 136
  start-page: 1049
  year: 1995
  end-page: 1058
  ident: bib235
  article-title: The 5′-flanking region of the ovine follicle-stimulating hormone–β gene contains six progesterone response elements: three proximal elements are sufficient to increase transcription in the presence of progesterone
  publication-title: Endocrinology
– volume: 20
  start-page: 1366
  year: 2006
  end-page: 1377
  ident: bib150
  article-title: Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function
  publication-title: Mol Endocrinol
– volume: 2
  start-page: 1237
  year: 1988
  end-page: 1242
  ident: bib35
  article-title: Recombinant expression and characterization of human activin A
  publication-title: Mol Endocrinol
– volume: 20
  start-page: 2062
  year: 2006
  end-page: 2079
  ident: bib188
  article-title: Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone β-subunit gene expression at the level of the gonadotrope
  publication-title: Mol Endocrinol
– volume: 15
  start-page: 331
  year: 2004
  end-page: 338
  ident: bib155
  article-title: Genomics view of gonadotrope signaling circuits
  publication-title: Trends Endocrinol Metab
– volume: 8
  start-page: 2302
  year: 1994
  end-page: 2312
  ident: bib120
  article-title: The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis
  publication-title: Genes Dev
– volume: 61
  start-page: 628
  year: 1995
  end-page: 637
  ident: bib240
  article-title: Hormonal regulation of human follicle-stimulating hormone–β subunit gene expression: GnRH stimulation and GnRH-independent androgen inhibition
  publication-title: Neuroendocrinology
– volume: 68
  start-page: 1877
  year: 2003
  end-page: 1887
  ident: bib199
  article-title: Activin signaling pathways in ovine pituitary and LβT2 gonadotrope cells
  publication-title: Biol Reprod
– volume: 374
  start-page: 356
  year: 1995
  end-page: 360
  ident: bib43
  article-title: Different phenotypes for mice deficient in either activins or activin receptor type II
  publication-title: Nature
– volume: 139
  start-page: 3289
  year: 1998
  end-page: 3295
  ident: bib228
  article-title: Genetic rescue of follicle-stimulating hormone β-deficient mice
  publication-title: Endocrinology
– volume: 7
  start-page: 66
  year: 2009
  ident: bib140
  article-title: Activin A induces ovine follicle stimulating hormone β using −169/−58 bp of its promoter and a simple TATA box
  publication-title: Reprod Biol Endocrinol
– volume: 2
  start-page: 653
  year: 2005
  end-page: 660
  ident: bib219
  article-title: Premature ovarian failure and forkhead transcription factor FOXL2: blepharophimosis–ptosis–epicanthus inversus syndrome and ovarian dysfunction
  publication-title: Pediatr Endocrinol Rev
– volume: 145
  start-page: 2228
  year: 2004
  end-page: 2244
  ident: bib165
  article-title: Extracellular signal–regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone–stimulated activity of the glycoprotein hormone follicle-stimulating hormone β-subunit promoter
  publication-title: Endocrinology
– volume: 136
  start-page: 67
  year: 1997
  end-page: 78
  ident: bib252
  article-title: A 361 base pair region of the rat FSH-β promoter contains multiple progesterone receptor–binding sequences and confers progesterone responsiveness
  publication-title: Mol Cell Endocrinol
– volume: 15
  start-page: 205
  year: 1997
  end-page: 206
  ident: bib7
  article-title: Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility
  publication-title: Nat Genet
– volume: 360
  start-page: 2742
  year: 2009
  end-page: 2748
  ident: bib16
  article-title: Isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation
  publication-title: N Engl J Med
– volume: 202
  start-page: 631
  year: 1978
  end-page: 633
  ident: bib21
  article-title: Hypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormone
  publication-title: Science
– volume: 149
  start-page: 20
  year: 2008
  end-page: 27
  ident: bib67
  article-title: Pituitary gonadotroph estrogen receptor-alpha is necessary for fertility in females
  publication-title: Endocrinology
– volume: 18
  start-page: 121
  year: 1997
  end-page: 132
  ident: bib92
  article-title: Local Ca
  publication-title: Neuron
– volume: 150
  start-page: 4802
  year: 2009
  end-page: 4809
  ident: bib70
  article-title: Developmental changes in pituitary PACAP expression during the perinatal period: possible role in fetal gonadotroph regulation
  publication-title: Endocrinology
– volume: 54
  start-page: 455
  year: 1999
  end-page: 484
  ident: bib106
  article-title: Regulation of glycoprotein hormone alpha-subunit gene expression
  publication-title: Recent Prog Horm Res
– volume: 271
  start-page: 6645
  year: 1996
  end-page: 6650
  ident: bib126
  article-title: Stimulation of luteinizing hormone β gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1
  publication-title: J Biol Chem
– volume: 118
  start-page: 1148
  year: 1986
  end-page: 1158
  ident: bib81
  article-title: Gonadotropin-releasing hormone stimulates mass changes in phosphoinositides and diacylglycerol accumulation in purified gonadotrope cell cultures
  publication-title: Endocrinology
– volume: 145
  start-page: 4866
  year: 2004
  end-page: 4879
  ident: bib132
  article-title: Regulation of the follicle-stimulating hormone β gene by the LHX3 LIM-homeodomain transcription factor
  publication-title: Endocrinology
– volume: 97
  start-page: 587
  year: 1999
  end-page: 598
  ident: bib148
  article-title: Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types
  publication-title: Cell
– volume: 142
  start-page: 139
  year: 2001
  end-page: 146
  ident: bib185
  article-title: Regulation of gonadotropin subunit gene transcription by gonadotropin-releasing hormone: measurement of primary transcript ribonucleic acids by quantitative reverse transcription–polymerase chain reaction assays
  publication-title: Endocrinology
– volume: 277
  start-page: 32099
  year: 2002
  end-page: 32108
  ident: bib183
  article-title: Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor–mediated signaling in L β T2 cells
  publication-title: J Biol Chem
– volume: 83
  start-page: 851
  year: 1998
  end-page: 858
  ident: bib45
  article-title: A two-site chemiluminescent assay for activin-free follistatin reveals that most follistatin circulating in men and normal cycling women is in an activin-bound state
  publication-title: J Clin Endocrinol Metab
– volume: 20
  start-page: 2909
  year: 2006
  end-page: 2930
  ident: bib225
  article-title: Activin modulates the transcriptional response of LβT2 cells to gonadotropin-releasing hormone and alters cellular proliferation
  publication-title: Mol Endocrinol
– volume: 81
  start-page: 243
  year: 2009
  end-page: 249
  ident: bib187
  article-title: Rapid effect of GNRH1 on follicle-stimulating hormone β gene expression in LβT2 mouse pituitary cells requires the progesterone receptor
  publication-title: Biol Reprod
– volume: 36
  start-page: 201
  year: 2006
  end-page: 220
  ident: bib207
  article-title: Acute regulation of murine follicle-stimulating hormone β subunit transcription by activin A
  publication-title: J Mol Endocrinol
– volume: 30
  start-page: 57
  year: 2009
  end-page: 66
  ident: bib64
  article-title: Kisspeptins and the control of gonadotropin secretion in male and female rodents
  publication-title: Peptides
– volume: 18
  start-page: 606
  year: 2004
  end-page: 623
  ident: bib111
  article-title: Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone β subunit in mouse gonadotrope cells
  publication-title: Mol Endocrinol
– volume: 30
  start-page: 154
  year: 2009
  end-page: 163
  ident: bib61
  article-title: Kisspeptin and seasonality in sheep
  publication-title: Peptides
– volume: 81
  start-page: 2742
  year: 1996
  end-page: 2745
  ident: bib55
  article-title: Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles
  publication-title: J Clin Endocrinol Metab
– volume: 212
  start-page: 19
  year: 2003
  end-page: 27
  ident: bib44
  article-title: Regulation of FSHβ and GnRH receptor gene expression in activin receptor II knockout male mice
  publication-title: Mol Cell Endocrinol
– volume: 159
  start-page: 103
  year: 1998
  end-page: 110
  ident: bib246
  article-title: Regulation of gonadotrophin secretion by inhibin, testosterone and gonadotrophin-releasing hormone in pituitary cell cultures of male monkeys
  publication-title: J Endocrinol
– volume: 81
  start-page: 693
  year: 2004
  end-page: 696
  ident: bib13
  article-title: Apparent primary follicle-stimulating hormone deficiency is a rare cause of treatable male infertility
  publication-title: Fertil Steril
– volume: 146
  start-page: 4340
  year: 2005
  end-page: 4348
  ident: bib191
  article-title: Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse
  publication-title: Endocrinology
– volume: 255
  start-page: 462
  year: 1992
  end-page: 464
  ident: bib90
  article-title: GnRH-induced Ca
  publication-title: Science
– volume: 145
  start-page: 387
  year: 1995
  end-page: 395
  ident: bib100
  article-title: Gonadotrophin secretion revisited. How many ways can FSH leave a gonadotroph?
  publication-title: J Endocrinol
– volume: 206
  start-page: 93
  year: 2003
  end-page: 111
  ident: bib221
  article-title: The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein
  publication-title: Mol Cell Endocrinol
– volume: 137
  start-page: 3437
  year: 1996
  end-page: 3446
  ident: bib261
  article-title: Transcriptional repression of the ovine follicle-stimulating hormone-β gene by 17β-estradiol
  publication-title: Endocrinology
– volume: 249
  start-page: 557
  year: 1986
  end-page: 562
  ident: bib96
  article-title: Gonadotropin release and redistribution of calcium-activated, phospholipid-dependent protein kinase in phorbol-stimulated rat pituitary cells
  publication-title: Arch Biochem Biophys
– volume: 272
  start-page: 24339
  year: 1997
  end-page: 24347
  ident: bib116
  article-title: Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin β-subunit promoter
  publication-title: J Biol Chem
– volume: 50
  start-page: 680
  year: 1994
  end-page: 685
  ident: bib20
  article-title: Continuous gonadotropin-releasing hormone infusion stimulates dramatic gonadal development in hypogonadal female mice
  publication-title: Biol Reprod
– volume: 32
  start-page: 467
  year: 2004
  end-page: 480
  ident: bib102
  article-title: Differential secretion of gonadotrophins: investigation of the role of secretogranin II and chromogranin A in the release of LH and FSH in LβT2 cells
  publication-title: J Mol Endocrinol
– volume: 8
  start-page: 647
  year: 1998
  end-page: 656
  ident: bib159
  article-title: Molecular mechanisms of the regulation of gonadotropin gene expression by gonadotropin-releasing hormone
  publication-title: Mol Cells
– volume: 79
  start-page: 947
  year: 2008
  end-page: 953
  ident: bib164
  article-title: Regulation of intracellular signaling cascades by GNRH pulse frequency in the rat pituitary: roles for CaMK II, ERK, and JNK activation
  publication-title: Biol Reprod
– volume: 77
  start-page: 241
  year: 1993
  end-page: 248
  ident: bib60
  article-title: Human recombinant activin-A alters pituitary luteinizing hormone and follicle-stimulating hormone secretion, follicular development, and steroidogenesis, during the menstrual cycle in rhesus monkeys
  publication-title: J Clin Endocrinol Metab
– volume: 25
  start-page: 521
  year: 2004
  end-page: 542
  ident: bib104
  article-title: Multiple and overlapping combinatorial codes orchestrate hormonal responsiveness and dictate cell-specific expression of the genes encoding luteinizing hormone
  publication-title: Endocr Rev
– volume: 82
  start-page: 8203
  year: 1985
  end-page: 8207
  ident: bib99
  article-title: Characterization of pituitary calcium-activated, phospholipid-dependent protein kinase: redistribution by gonadotropin-releasing hormone
  publication-title: Proc Natl Acad Sci U S A
– volume: 162
  start-page: R1
  year: 1999
  end-page: R5
  ident: bib114
  article-title: LβT2 gonadotroph cells secrete follicle stimulating hormone (FSH) in response to activin A
  publication-title: J Endocrinol
– volume: 42
  start-page: 1117
  year: 1994
  end-page: 1125
  ident: bib110
  article-title: In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development
  publication-title: J Histochem Cytochem
– volume: 124
  start-page: 2807
  year: 1997
  end-page: 2817
  ident: bib144
  article-title: The bicoid-related homeoprotein Ptx1 defines the most anterior domain of the embryo and differentiates posterior from anterior lateral mesoderm
  publication-title: Development
– volume: 260
  start-page: 3243
  year: 1985
  end-page: 3246
  ident: bib95
  article-title: Hormone-induced redistribution of calcium-activated phospholipid-dependent protein kinase in pituitary gonadotrophs
  publication-title: J Biol Chem
– volume: 14
  start-page: 1235
  year: 2000
  end-page: 1245
  ident: bib127
  article-title: Sp1, steroidogenic factor 1 (SF-1), and early growth response protein 1 (EGR-1) binding sites form a tripartite gonadotropin-releasing hormone response element in the rat luteinizing hormone-β gene promoter: an integral role for SF-1
  publication-title: Mol Endocrinol
– volume: 13
  start-page: 1497
  year: 1999
  end-page: 1510
  ident: bib130
  article-title: The equine luteinizing hormone β-subunit promoter contains two functional steroidogenic factor-1 response elements
  publication-title: Mol Endocrinol
– volume: 148
  start-page: 1099
  year: 2007
  end-page: 1107
  ident: bib182
  article-title: Gonadotropin-releasing hormone couples to 3′,5′-cyclic adenosine-5′-monophosphate pathway through novel protein kinase Cdelta and -epsilon in LβT2 gonadotrope cells
  publication-title: Endocrinology
– volume: 142
  start-page: 2267
  year: 2001
  end-page: 2274
  ident: bib180
  article-title: Transcriptional regulation of the ovine follicle-stimulating hormone–β gene by activin and gonadotropin-releasing hormone (GnRH): involvement of two proximal activator protein-1 sites for GnRH stimulation
  publication-title: Endocrinology
– volume: 146
  start-page: 4814
  year: 2005
  end-page: 4824
  ident: bib224
  article-title: Transforming growth factor β–activated kinase 1 is a key mediator of ovine follicle-stimulating hormone β-subunit expression
  publication-title: Endocrinology
– volume: 16
  start-page: 1840
  year: 2002
  end-page: 1852
  ident: bib139
  article-title: Pituitary homeobox 1 activates the rat FSHβ (rFSHβ) gene through both direct and indirect interactions with the rFSHβ gene promoter
  publication-title: Mol Endocrinol
– volume: 18
  start-page: 1158
  year: 2004
  end-page: 1170
  ident: bib208
  article-title: Activin regulation of the follicle-stimulating hormone β-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1
  publication-title: Mol Endocrinol
– volume: 207
  start-page: 668
  year: 2006
  end-page: 674
  ident: bib97
  article-title: Heterogeneity of the Ca
  publication-title: J Cell Physiol
– volume: 11
  start-page: 309
  year: 2000
  end-page: 314
  ident: bib198
  article-title: Activin signal transduction pathways
  publication-title: Trends Endocrinol Metab
– volume: 170
  start-page: 601
  year: 2001
  end-page: 607
  ident: bib234
  article-title: Androgen responsiveness of the pituitary gonadotrope cell line LβT2
  publication-title: J Endocrinol
– volume: 139
  start-page: 4455
  year: 1998
  end-page: 4465
  ident: bib175
  article-title: Transcriptional activation of the ovine follicle-stimulating hormone β-subunit gene by gonadotropin-releasing hormone: involvement of two activating protein-1–binding sites and protein kinase C
  publication-title: Endocrinology
– volume: 87
  start-page: 8855
  year: 1990
  end-page: 8859
  ident: bib94
  article-title: Dependence of hormone secretion on activation-inactivation kinetics of voltage-sensitive Ca
  publication-title: Proc Natl Acad Sci U S A
– volume: 182
  start-page: 1408
  year: 1992
  end-page: 1415
  ident: bib51
  article-title: Effects of activin A and somatostatin on intact FSH secretion and intracellular Ca
  publication-title: Biochem Biophys Res Commun
– volume: 30
  start-page: 94
  year: 2009
  end-page: 102
  ident: bib66
  article-title: Sex steroid control of hypothalamic Kiss1 expression in sheep and rodents: comparative aspects
  publication-title: Peptides
– volume: 203
  start-page: 169
  year: 2003
  end-page: 183
  ident: bib273
  article-title: Pituitary tumorigenesis targeted by the ovine follicle-stimulating hormone β-subunit gene regulatory region in transgenic mice
  publication-title: Mol Cell Endocrinol
– volume: 3
  start-page: 131
  year: 2000
  end-page: 139
  ident: bib49
  article-title: Localization of inhibin/activin subunits in normal pituitary and in pituitary adenomas
  publication-title: Pituitary
– volume: 1
  start-page: 611
  year: 1998
  end-page: 617
  ident: bib213
  article-title: Human Smad3 and Smad4 are sequence-specific transcription activators
  publication-title: Mol Cell
– volume: 96
  start-page: 25
  year: 1993
  end-page: 36
  ident: bib275
  article-title: The FSH β-subunit promoter directs the expression of Herpes simplex virus type 1 thymidine kinase to the testis of transgenic mice
  publication-title: Mol Cell Endocrinol
– volume: 51
  start-page: 23
  year: 1996
  end-page: 58
  ident: bib105
  article-title: The gonadotropin genes: evolution of distinct mechanisms for hormonal control
  publication-title: Recent Prog Horm Res
– volume: 90
  start-page: 826
  year: 2005
  end-page: 830
  ident: bib57
  article-title: Relationship of estradiol and inhibin to the follicle-stimulating hormone variability in hypergonadotropic hypogonadism or premature ovarian failure
  publication-title: J Clin Endocrinol Metab
– volume: 4
  start-page: 721
  year: 1990
  end-page: 726
  ident: bib195
  article-title: Rapid stimulatory effect of activin-A on messenger RNA encoding the follicle-stimulating hormone β-subunit in rat pituitary cell cultures
  publication-title: Mol Endocrinol
– volume: 4
  start-page: 52
  year: 2006
  ident: bib202
  article-title: Activin B can signal through both ALK4 and ALK7 in gonadotrope cells
  publication-title: Reprod Biol Endocrinol
– volume: 83
  start-page: 466
  year: 2005
  end-page: 470
  ident: bib10
  article-title: Clinical and hormonal features of selective follicle-stimulating hormone (FSH) deficiency due to FSH β-subunit gene mutations in both sexes
  publication-title: Fertil Steril
– volume: 104
  start-page: 31
  year: 1993
  end-page: 46
  ident: bib19
  article-title: GnRH pulses—the regulators of human reproduction
  publication-title: Trans Am Clin Climatol Assoc
– volume: 117
  start-page: 2443
  year: 1985
  end-page: 2448
  ident: bib238
  article-title: Progesterone inhibits basal production of follicle-stimulating hormone in ovine pituitary cell culture
  publication-title: Endocrinology
– volume: 17
  start-page: 318
  year: 2003
  end-page: 332
  ident: bib138
  article-title: Regulation of the rat follicle-stimulating hormone β-subunit promoter by activin
  publication-title: Mol Endocrinol
– volume: 30
  start-page: 67
  year: 2009
  end-page: 75
  ident: bib63
  article-title: Kisspeptin and the regulation of the hypothalamic-pituitary-gonadal axis in the rhesus monkey (
  publication-title: Peptides
– volume: 19
  start-page: 2567
  year: 1999
  end-page: 2576
  ident: bib128
  article-title: Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone β gene transcription
  publication-title: Mol Cell Biol
– volume: 44
  start-page: 1
  year: 1988
  end-page: 34
  ident: bib23
  article-title: Chemical and biological characterization of the inhibin family of protein hormones
  publication-title: Recent Prog Horm Res
– volume: 30
  start-page: 10
  year: 2009
  end-page: 29
  ident: bib153
  article-title: Signaling by G-protein–coupled receptor (GPCR): studies on the GnRH receptor
  publication-title: Front Neuroendocrinol
– volume: 36
  start-page: 663
  year: 1998
  end-page: 665
  ident: bib11
  article-title: Follitropin (FSH) deficiency in an infertile male due to FSHβ gene mutation. A syndrome of normal puberty and virilization but underdeveloped testicles with azoospermia, low FSH but high lutropin and normal serum testosterone concentrations
  publication-title: Clin Chem Lab Med
– volume: 10
  start-page: 356
  year: 1996
  end-page: 366
  ident: bib230
  article-title: Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A
  publication-title: Mol Endocrinol
– volume: 134
  start-page: 861
  year: 1986
  end-page: 867
  ident: bib82
  article-title: Gonadotropin releasing hormone enhances polyphosphoinositide hydrolysis in rat pituitary cells
  publication-title: Biochem Biophys Res Commun
– volume: 23
  start-page: 1001
  year: 2009
  end-page: 1013
  ident: bib212
  article-title: A novel role for the forkhead transcription factor FOXL2 in activin A–regulated follicle-stimulating hormone β subunit transcription
  publication-title: Mol Endocrinol
– volume: 125
  start-page: 2787
  year: 1989
  end-page: 2789
  ident: bib58
  article-title: Recombinant human activin-A stimulates basal FSH and GnRH-stimulated FSH and LH release in the adult male macaque, Macaca fascicularis
  publication-title: Endocrinology
– volume: 13
  start-page: 1338
  year: 1999
  end-page: 1352
  ident: bib186
  article-title: Estradiol suppresses phosphorylation of cyclic adenosine 3′,5′-monophosphate response element binding protein (CREB) in the pituitary: evidence for indirect action via gonadotropin-releasing hormone
  publication-title: Mol Endocrinol
– volume: 129
  start-page: 1721
  year: 1991
  end-page: 1726
  ident: bib209
  article-title: Activin stabilizes follicle-stimulating hormone–β messenger ribonucleic acid levels
  publication-title: Endocrinology
– volume: 23
  start-page: 1092
  year: 2009
  end-page: 1101
  ident: bib171
  article-title: ERK signaling in the pituitary is required for female but not male fertility
  publication-title: Mol Endocrinol
– volume: 88
  start-page: 225
  year: 2006
  end-page: 234
  ident: bib217
  article-title: Foxl2 function in ovarian development
  publication-title: Mol Genet Metab
– volume: 129
  start-page: 329
  year: 2002
  end-page: 337
  ident: bib142
  article-title: Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification
  publication-title: Development
– volume: 20
  start-page: 6127
  year: 2000
  end-page: 6137
  ident: bib33
  article-title: Activin βC and βE genes are not essential for mouse liver growth, differentiation, and regeneration
  publication-title: Mol Cell Biol
– volume: 261
  start-page: 12506
  year: 1986
  end-page: 12512
  ident: bib84
  article-title: Gonadotropin-releasing hormone activates a rapid Ca
  publication-title: J Biol Chem
– volume: 143
  start-page: 2250
  year: 2002
  end-page: 2258
  ident: bib244
  article-title: Paracrine regulation of FSH by follistatin in folliculostellate cell–enriched primate pituitary cell cultures
  publication-title: Endocrinology
– volume: 186
  start-page: 109
  year: 2005
  end-page: 121
  ident: bib72
  article-title: BMP-4 inhibits follicle-stimulating hormone secretion in ewe pituitary
  publication-title: J Endocrinol
– volume: 62
  start-page: 636
  year: 2000
  end-page: 641
  ident: bib253
  article-title: Follistatin suppresses steroid-enhanced follicle-stimulating hormone release in vitro in rats
  publication-title: Biol Reprod
– volume: 154
  start-page: 398
  year: 1988
  end-page: 403
  ident: bib89
  article-title: Biphasic activation of cytosolic free calcium and LH responses by gonadotropin-releasing hormone
  publication-title: Biochem Biophys Res Commun
– volume: 260
  start-page: 82
  year: 1993
  end-page: 84
  ident: bib91
  article-title: Rhythmic exocytosis stimulated by GnRH-induced calcium oscillations in rat gonadotropes
  publication-title: Science
– volume: 128
  start-page: 147
  year: 2001
  end-page: 154
  ident: bib122
  article-title: Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function
  publication-title: Development
– volume: 149
  start-page: 133
  year: 1987
  end-page: 139
  ident: bib29
  article-title: Follistatin specifically inhibits pituitary follicle stimulating hormone release in vitro
  publication-title: Biochem Biophys Res Commun
– volume: 173
  start-page: 1
  year: 2002
  end-page: 11
  ident: bib152
  article-title: Signalling, cycling and desensitisation of gonadotrophin-releasing hormone receptors
  publication-title: J Endocrinol
– volume: 139
  start-page: 3104
  year: 1998
  end-page: 3111
  ident: bib163
  article-title: Gonadotropin-releasing hormone pulses are required to maintain activation of mitogen-activated protein kinase: role in stimulation of gonadotrope gene expression
  publication-title: Endocrinology
– volume: 74
  start-page: 993
  year: 2006
  end-page: 998
  ident: bib18
  article-title: Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1
  publication-title: Biol Reprod
– year: 2009
  ident: bib177
  article-title: Gonadotropin releasing hormone-mediated phosphorylation of estrogen receptor α contributes to fosB expression in mouse gonadotrophs
  publication-title: Endocrinology
– volume: 15
  start-page: 77
  year: 2009
  end-page: 87
  ident: bib121
  article-title: Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone β subunit transcription
  publication-title: Mol Hum Reprod
– volume: 4
  start-page: 1943
  year: 1990
  end-page: 1955
  ident: bib232
  article-title: Gonadotropin subunit messenger RNA concentrations after blockade of gonadotropin-releasing hormone action: testosterone selectively increases follicle-stimulating hormone β-subunit messenger RNA by posttranscriptional mechanisms
  publication-title: Mol Endocrinol
– volume: 33
  start-page: 559
  year: 2004
  end-page: 584
  ident: bib156
  article-title: Regulation of gonadotropin subunit gene transcription
  publication-title: J Mol Endocrinol
– volume: 69
  start-page: 1160
  year: 2009
  ident: bib56
  article-title: ACE-011, a soluble activin receptor type IIA IgG-Fc fusion protein, decreases follicle stimulating hormone and increases bone-specific alkaline phosphatase, a marker of bone formation, in postmenopausal healthy women
  publication-title: Cancer Res
– volume: 277
  start-page: 44408
  year: 2002
  end-page: 44416
  ident: bib118
  article-title: Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter
  publication-title: J Biol Chem
– volume: 15
  start-page: 201
  year: 1997
  end-page: 204
  ident: bib4
  article-title: Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility
  publication-title: Nat Genet
– volume: 144
  start-page: 1802
  year: 2003
  end-page: 1811
  ident: bib157
  article-title: Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L β T2 cells: role of GnRH receptor concentration
  publication-title: Endocrinology
– volume: 6
  start-page: 81
  year: 1992
  end-page: 90
  ident: bib227
  article-title: Gonadotrope-specific expression of the human follicle-stimulating hormone β-subunit gene in pituitaries of transgenic mice
  publication-title: Mol Endocrinol
– volume: 53–54
  start-page: 187
  year: 1983
  end-page: 195
  ident: bib260
  article-title: Regulation of β-chain mRNA of ovine follicle-stimulating hormone by 17β-estradiol
  publication-title: Mol Cell Biochem
– volume: 145
  start-page: 5832
  year: 2004
  end-page: 5839
  ident: bib107
  article-title: Rapid, efficient isolation of murine gonadotropes and their use in revealing control of follicle-stimulating hormone by paracrine pituitary factors
  publication-title: Endocrinology
– volume: 274
  start-page: 13870
  year: 1999
  end-page: 13876
  ident: bib124
  article-title: Activation of luteinizing hormone β gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1
  publication-title: J Biol Chem
– volume: 273
  start-page: 14712
  year: 1998
  end-page: 14720
  ident: bib125
  article-title: Steroidogenic factor-1 and early growth response protein 1 act through two composite DNA binding sites to regulate luteinizing hormone β-subunit gene expression
  publication-title: J Biol Chem
– volume: 14
  start-page: 5592
  year: 1994
  end-page: 5602
  ident: bib149
  article-title: GATA-binding proteins regulate the human gonadotropin alpha-subunit gene in the placenta and pituitary gland
  publication-title: Mol Cell Biol
– volume: 234
  start-page: 1366
  year: 1986
  end-page: 1371
  ident: bib14
  article-title: A deletion truncating the gonadotropin-releasing hormone gene is responsible for hypogonadism in the hpg mouse
  publication-title: Science
– volume: 124
  start-page: 267
  year: 2002
  end-page: 277
  ident: bib79
  article-title: Promotion of intragranular co-aggregation with LH by enhancement of secretogranin II storage resulted in increased intracellular granule storage in gonadotrophs of GnRH-deprived male mice
  publication-title: Reproduction
– volume: 45
  start-page: 377
  year: 2005
  end-page: 382
  ident: bib220
  article-title: Foxl2 gene and the development of the ovary: a story about goat, mouse, fish and woman
  publication-title: Reprod Nutr Dev
– volume: 81
  start-page: 488
  year: 2009
  end-page: 496
  ident: bib68
  article-title: Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1)
  publication-title: Biol Reprod
– volume: 225
  start-page: 29
  year: 2004
  end-page: 36
  ident: bib25
  article-title: Autocrine/paracrine regulation of pituitary function by activin, inhibin and follistatin
  publication-title: Mol Cell Endocrinol
– volume: 81
  start-page: 3328
  year: 1996
  end-page: 3334
  ident: bib46
  article-title: Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy
  publication-title: J Clin Endocrinol Metab
– volume: 17
  start-page: 1470
  year: 2003
  end-page: 1483
  ident: bib133
  article-title: Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse follicle-stimulating hormone–β gene
  publication-title: Mol Endocrinol
– volume: 196
  start-page: 497
  year: 2008
  end-page: 507
  ident: bib75
  article-title: Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LβT2 gonadotrophs
  publication-title: J Endocrinol
– volume: 79
  start-page: 434
  year: 2003
  end-page: 436
  ident: bib12
  article-title: Isolated follicle-stimulating hormone (FSH) deficiency in a young man with normal virilization who did not have mutations in the FSHβ gene
  publication-title: Fertil Steril
– volume: 137
  start-page: 3667
  year: 1996
  end-page: 3673
  ident: bib231
  article-title: Gonadotropin-releasing hormone regulates follicle-stimulating hormone–β gene expression through an activin/follistatin autocrine or paracrine loop
  publication-title: Endocrinology
– volume: 95
  start-page: 13612
  year: 1998
  end-page: 13617
  ident: bib6
  article-title: Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance
  publication-title: Proc Natl Acad Sci U S A
– volume: 142
  start-page: 2275
  year: 2001
  end-page: 2283
  ident: bib74
  article-title: A novel role for bone morphogenetic proteins in the synthesis of follicle-stimulating hormone
  publication-title: Endocrinology
– volume: 13
  start-page: 484
  year: 1999
  end-page: 494
  ident: bib143
  article-title: Role of the bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development
  publication-title: Genes Dev
– volume: 137
  start-page: 85
  year: 1996
  end-page: 89
  ident: bib248
  article-title: Mechanism of the inhibitory action of RU486 on the secondary follicle-stimulating hormone surge
  publication-title: Endocrinology
– volume: 279
  start-page: 152
  year: 2004
  end-page: 162
  ident: bib167
  article-title: A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone β gene by gonadotropin-releasing hormone
  publication-title: J Biol Chem
– volume: 143
  start-page: 1651
  year: 2002
  end-page: 1659
  ident: bib169
  article-title: Transcriptional activation of the ovine follicle-stimulating hormone–β gene by gonadotropin-releasing hormone involves multiple signal transduction pathways
  publication-title: Endocrinology
– volume: 22
  start-page: 1908
  year: 2008
  end-page: 1923
  ident: bib181
  article-title: A composite element that binds basic helix loop helix and basic leucine zipper transcription factors is important for gonadotropin-releasing hormone regulation of the follicle-stimulating hormone β gene
  publication-title: Mol Endocrinol
– volume: 38
  start-page: 315
  year: 2007
  end-page: 330
  ident: bib40
  article-title: Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone β subunit transcription
  publication-title: J Mol Endocrinol
– volume: 83
  start-page: 851
  year: 1995
  end-page: 857
  ident: bib251
  article-title: Steroid hormone receptors: many actors in search of a plot
  publication-title: Cell
– volume: 96
  start-page: 285
  year: 1991
  end-page: 293
  ident: bib80
  article-title: Topology of chromogranin A and secretogranin II in the rat anterior pituitary: potential marker proteins for distinct secretory pathways in gonadotrophs
  publication-title: Histochemistry
– volume: 196
  start-page: 251
  year: 2008
  end-page: 261
  ident: bib77
  article-title: The activin receptor-like kinase 6 Booroola mutation enhances suppressive effects of bone morphogenetic protein 2 (BMP2), BMP4, BMP6 and growth and differentiation factor-9 on FSH release from ovine primary pituitary cell cultures
  publication-title: J Endocrinol
– volume: 404
  start-page: 411
  year: 2000
  end-page: 414
  ident: bib27
  article-title: β-Glycan binds inhibin and can mediate functional antagonism of activin signalling
  publication-title: Nature
– volume: 7
  start-page: 668
  year: 1993
  end-page: 680
  ident: bib210
  article-title: Decay of follicle-stimulating hormone–β messenger RNA in the presence of transcriptional inhibitors and/or inhibin, activin, or follistatin
  publication-title: Mol Endocrinol
– volume: 21
  start-page: 3071
  year: 2007
  end-page: 3086
  ident: bib166
  article-title: p38 mitogen-activated protein kinase is critical for synergistic induction of the FSH(β) gene by gonadotropin-releasing hormone and activin through augmentation of c-Fos induction and Smad phosphorylation
  publication-title: Mol Endocrinol
– volume: 32
  start-page: 391
  year: 1985
  end-page: 398
  ident: bib269
  article-title: Effect of gonadotropin-releasing hormone antagonists on serum follicle-stimulating hormone and luteinizing hormone under conditions of singular follicle-stimulating hormone secretion
  publication-title: Biol Reprod
– volume: 252
  start-page: 167
  year: 2006
  end-page: 183
  ident: bib267
  article-title: Transcription of gonadotropin β subunit genes involves cross-talk between the transcription factors and co-regulators that mediate actions of the regulatory hormones
  publication-title: Mol Cell Endocrinol
– volume: 86
  start-page: 4501
  year: 1989
  end-page: 4504
  ident: bib98
  article-title: Induction of exocytosis in permeabilized pituitary cells by alpha- and β-type protein kinase C
  publication-title: Proc Natl Acad Sci U S A
– volume: 2
  start-page: 272
  year: 1990
  end-page: 283
  ident: bib88
  article-title: Generation and amplification of the cytosolic calcium signal during secretory responses to gonadotropin-releasing hormone
  publication-title: New Biol
– volume: 281
  start-page: 27
  year: 2008
  end-page: 36
  ident: bib137
  article-title: Smad3 and Pitx2 cooperate in stimulation of FSHβ gene transcription
  publication-title: Mol Cell Endocrinol
– volume: 104
  start-page: 849
  year: 2001
  end-page: 859
  ident: bib115
  article-title: A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins
  publication-title: Cell
– volume: 252
  start-page: 184
  year: 2006
  end-page: 190
  ident: bib154
  article-title: Activation of mitogen-activated protein kinase (MAPK) by GnRH is cell-context dependent
  publication-title: Mol Cell Endocrinol
– volume: 68
  start-page: 1145
  year: 2004
  end-page: 1155
  ident: bib184
  article-title: CBP and p300: HATs for different occasions
  publication-title: Biochem Pharmacol
– volume: 128
  start-page: 13
  year: 2004
  end-page: 23
  ident: bib245
  article-title: Intra-pituitary regulation of gonadotrophs in male rodents and primates
  publication-title: Reproduction
– volume: 149
  start-page: 139
  year: 2008
  end-page: 145
  ident: bib174
  article-title: Pulsatile gonadotropin-releasing hormone stimulation of gonadotropin subunit transcription in rat pituitaries: evidence for the involvement of Jun N-terminal kinase but not p38
  publication-title: Endocrinology
– volume: 5
  start-page: 949
  year: 1991
  end-page: 958
  ident: bib85
  article-title: Spontaneous and agonist-induced calcium oscillations in pituitary gonadotrophs
  publication-title: Mol Endocrinol
– volume: 23
  start-page: 402
  year: 2009
  end-page: 411
  ident: bib178
  article-title: GnRH-regulated expression of Jun and JUN target genes in gonadotropes requires a functional interaction between TCF/LEF family members and β-catenin
  publication-title: Mol Endocrinol
– volume: 143
  start-page: 2839
  year: 2002
  end-page: 2851
  ident: bib119
  article-title: Regulation of prolactin, GH, and Pit-1 gene expression in anterior pituitary by Pitx2: an approach using Pitx2 mutants
  publication-title: Endocrinology
– volume: 19
  start-page: 1893
  year: 2005
  end-page: 1903
  ident: bib134
  article-title: PITX genes are required for cell survival and Lhx3 activation
  publication-title: Mol Endocrinol
– volume: 113
  start-page: 535
  year: 1983
  end-page: 544
  ident: bib17
  article-title: The effects of daily administration of single and multiple injections of gonadotropin-releasing hormone on pituitary and gonadal function in the hypogonadal (hpg) mouse
  publication-title: Endocrinology
– volume: 3
  start-page: 474
  year: 1989
  end-page: 480
  ident: bib263
  article-title: Divergent effects of estradiol on gonadotropin gene transcription in pituitary fragments
  publication-title: Mol Endocrinol
– volume: 124
  start-page: 552
  year: 1989
  end-page: 554
  ident: bib39
  article-title: Production and regulation of inhibin subunits in pituitary gonadotropes
  publication-title: Endocrinology
– volume: 149
  start-page: 5577
  year: 2008
  end-page: 5591
  ident: bib170
  article-title: Activator protein-1 and Smad proteins synergistically regulate human follicle-stimulating hormone β-promoter activity
  publication-title: Endocrinology
– volume: 149
  start-page: 1091
  year: 2008
  end-page: 1102
  ident: bib189
  article-title: Synergistic induction of follicle-stimulating hormone β-subunit gene expression by gonadal steroid hormone receptors and Smad proteins
  publication-title: Endocrinology
– volume: 140
  start-page: 2415
  year: 1999
  end-page: 2421
  ident: bib274
  article-title: The gonadotropin-releasing hormone receptor gene promoter directs pituitary-specific oncogene expression in transgenic mice
  publication-title: Endocrinology
– volume: 21
  start-page: 551
  year: 2000
  end-page: 583
  ident: bib2
  article-title: Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function
  publication-title: Endocr Rev
– volume: 72
  start-page: 1286
  year: 1991
  end-page: 1289
  ident: bib22
  article-title: The importance of signal pattern in the transmission of endocrine information: pituitary gonadotropin responses to continuous and pulsatile gonadotropin-releasing hormone
  publication-title: J Clin Endocrinol Metab
– volume: 128
  start-page: 509
  year: 1991
  end-page: 517
  ident: bib162
  article-title: A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo
  publication-title: Endocrinology
– volume: 25
  start-page: 182
  year: 2000
  end-page: 186
  ident: bib145
  article-title: Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency
  publication-title: Nat Genet
– volume: 194
  start-page: 413
  year: 1993
  end-page: 419
  ident: bib255
  article-title: Interaction of activin A and gonadal steroids on FSH secretion from primary cultured rat anterior pituitary cells
  publication-title: Biochem Biophys Res Commun
– volume: 2
  start-page: 641
  year: 1988
  end-page: 649
  ident: bib258
  article-title: 17β-Estradiol and progesterone inhibit transcription of the genes encoding the subunits of ovine follicle-stimulating hormone
  publication-title: Mol Endocrinol
– volume: 148
  start-page: 762
  year: 2007
  end-page: 773
  ident: bib206
  article-title: Activin and glucocorticoids synergistically activate follicle-stimulating hormone β-subunit gene expression in the immortalized LβT2 gonadotrope cell line
  publication-title: Endocrinology
– volume: 123
  start-page: 2946
  year: 1988
  end-page: 2948
  ident: bib270
  article-title: Follicle-stimulating hormone β subunit messenger ribonucleic acid concentrations during the rat estrous cycle
  publication-title: Endocrinology
– volume: 136
  start-page: 1885
  year: 1995
  end-page: 1891
  ident: bib112
  article-title: Transcriptional activation of the follicle-stimulating hormone β-subunit gene by activin
  publication-title: Endocrinology
– volume: 74
  start-page: 600
  year: 1992
  end-page: 607
  ident: bib268
  article-title: Hypothalamic gonadotropin-releasing hormone secretion and follicle-stimulating hormone dynamics during the luteal-follicular transition
  publication-title: J Clin Endocrinol Metab
– volume: 425
  start-page: 577
  year: 2003
  end-page: 584
  ident: bib223
  article-title: Smad-dependent and Smad-independent pathways in TGF-β family signalling
  publication-title: Nature
– volume: 196
  start-page: 53
  year: 2002
  end-page: 66
  ident: bib117
  article-title: Domains of Pit-1 required for transcriptional synergy with GATA-2 on the TSH β gene
  publication-title: Mol Cell Endocrinol
– volume: 36
  start-page: 591
  year: 2006
  end-page: 600
  ident: bib200
  article-title: Cell-specificity of transforming growth factor-β response is dictated by receptor bioavailability
  publication-title: J Mol Endocrinol
– volume: 27
  start-page: 4105
  year: 2007
  end-page: 4120
  ident: bib192
  article-title: Distinct mechanisms involving diverse histone deacetylases repress expression of the two gonadotropin β-subunit genes in immature gonadotropes, and their actions are overcome by gonadotropin-releasing hormone
  publication-title: Mol Cell Biol
– volume: 72
  start-page: 1261
  year: 1991
  end-page: 1267
  ident: bib50
  article-title: The effects of activin on follicle-stimulating hormone secretion and biosynthesis in human glycoprotein hormone-producing pituitary adenomas
  publication-title: J Clin Endocrinol Metab
– volume: 247
  start-page: 103
  year: 2006
  end-page: 115
  ident: bib229
  article-title: Gonadotroph-specific expression of the human follicle stimulating hormone β gene in transgenic mice
  publication-title: Mol Cell Endocrinol
– volume: 17
  start-page: 1470
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib133
  article-title: Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse follicle-stimulating hormone–β gene
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2002-0286
– volume: 207
  start-page: 668
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib97
  article-title: Heterogeneity of the Ca2+ sensitivity of secretion in a pituitary gonadotrope cell line and its modulation by protein kinase C and Ca2+
  publication-title: J Cell Physiol
  doi: 10.1002/jcp.20598
– volume: 46
  start-page: 220
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib247
  article-title: RU486 blocks the secondary surge of follicle-stimulating hormone in the rat without blocking the drop in serum inhibin
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod46.2.220
– volume: 277
  start-page: 44408
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib118
  article-title: Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M207824200
– volume: 62
  start-page: 636
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib253
  article-title: Follistatin suppresses steroid-enhanced follicle-stimulating hormone release in vitro in rats
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod62.3.636
– volume: 20
  start-page: 1366
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib150
  article-title: Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2005-0378
– volume: 174
  start-page: 179
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib78
  article-title: Co-localisation of gonadotrophins and granins in gonadotrophs at different stages of the oestrous cycle in sheep
  publication-title: J Endocrinol
  doi: 10.1677/joe.0.1740179
– volume: 9
  start-page: 267
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib24
  article-title: Inhibins, activins, and follistatins: gonadal proteins modulating the secretion of follicle-stimulating hormone
  publication-title: Endocr Rev
  doi: 10.1210/edrv-9-2-267
– volume: 188
  start-page: 254
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib26
  article-title: Antagonism of activin by inhibin and inhibin receptors: a functional role for βglycan
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/S0303-7207(02)00037-0
– volume: 30
  start-page: 10
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib153
  article-title: Signaling by G-protein–coupled receptor (GPCR): studies on the GnRH receptor
  publication-title: Front Neuroendocrinol
  doi: 10.1016/j.yfrne.2008.07.001
– volume: 139
  start-page: 3104
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib163
  article-title: Gonadotropin-releasing hormone pulses are required to maintain activation of mitogen-activated protein kinase: role in stimulation of gonadotrope gene expression
  publication-title: Endocrinology
  doi: 10.1210/endo.139.7.6091
– volume: 30
  start-page: 154
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib61
  article-title: Kisspeptin and seasonality in sheep
  publication-title: Peptides
  doi: 10.1016/j.peptides.2008.08.022
– volume: 4
  start-page: 721
  year: 1990
  ident: 10.1016/j.fertnstert.2010.03.034_bib195
  article-title: Rapid stimulatory effect of activin-A on messenger RNA encoding the follicle-stimulating hormone β-subunit in rat pituitary cell cultures
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-4-5-721
– volume: 272
  start-page: 1004
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib146
  article-title: Specification of pituitary cell lineages by the LIM homeobox gene Lhx3
  publication-title: Science
  doi: 10.1126/science.272.5264.1004
– volume: 170
  start-page: 359
  year: 1990
  ident: 10.1016/j.fertnstert.2010.03.034_bib93
  article-title: Role of voltage-sensitive calcium channels in [Ca2+]i and secretory responses to activators of protein kinase C in pituitary gonadotrophs
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/0006-291X(90)91282-W
– volume: 108
  start-page: 673
  year: 1981
  ident: 10.1016/j.fertnstert.2010.03.034_bib259
  article-title: Estrogen regulation of follicle-stimulating hormone production in vitro: species variation
  publication-title: Endocrinology
  doi: 10.1210/endo-108-2-673
– volume: 2
  start-page: 272
  year: 1990
  ident: 10.1016/j.fertnstert.2010.03.034_bib88
  article-title: Generation and amplification of the cytosolic calcium signal during secretory responses to gonadotropin-releasing hormone
  publication-title: New Biol
– volume: 1
  start-page: 611
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib213
  article-title: Human Smad3 and Smad4 are sequence-specific transcription activators
  publication-title: Mol Cell
  doi: 10.1016/S1097-2765(00)80061-1
– volume: 338
  start-page: 1729
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib9
  article-title: Male hypogonadism due to a mutation in the gene for the β-subunit of follicle-stimulating hormone
  publication-title: N Engl J Med
  doi: 10.1056/NEJM199806113382404
– volume: 252
  start-page: 184
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib154
  article-title: Activation of mitogen-activated protein kinase (MAPK) by GnRH is cell-context dependent
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2006.03.035
– volume: 149
  start-page: 5577
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib170
  article-title: Activator protein-1 and Smad proteins synergistically regulate human follicle-stimulating hormone β-promoter activity
  publication-title: Endocrinology
  doi: 10.1210/en.2008-0220
– volume: 124
  start-page: 552
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib39
  article-title: Production and regulation of inhibin subunits in pituitary gonadotropes
  publication-title: Endocrinology
  doi: 10.1210/endo-124-1-552
– volume: 30
  start-page: 94
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib66
  article-title: Sex steroid control of hypothalamic Kiss1 expression in sheep and rodents: comparative aspects
  publication-title: Peptides
  doi: 10.1016/j.peptides.2008.08.013
– volume: 81
  start-page: 133
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib73
  article-title: Bone morphogenetic protein 2 signals via BMPR1A to regulate murine follicle-stimulating hormone β subunit transcription
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.108.074211
– volume: 277
  start-page: 32099
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib183
  article-title: Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor–mediated signaling in L β T2 cells
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M203639200
– volume: 10
  start-page: 356
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib230
  article-title: Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A
  publication-title: Mol Endocrinol
– volume: 143
  start-page: 2250
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib244
  article-title: Paracrine regulation of FSH by follistatin in folliculostellate cell–enriched primate pituitary cell cultures
  publication-title: Endocrinology
  doi: 10.1210/endo.143.6.8857
– volume: 146
  start-page: 5503
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib158
  article-title: Gonadotropin-releasing hormone pulse frequency–dependent activation of extracellular signal-regulated kinase pathways in perifused LβT2 cells
  publication-title: Endocrinology
  doi: 10.1210/en.2004-1317
– volume: 2
  start-page: 641
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib258
  article-title: 17β-Estradiol and progesterone inhibit transcription of the genes encoding the subunits of ovine follicle-stimulating hormone
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-2-7-641
– volume: 269
  start-page: 338
  year: 1977
  ident: 10.1016/j.fertnstert.2010.03.034_bib15
  article-title: Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism
  publication-title: Nature
  doi: 10.1038/269338a0
– volume: 137
  start-page: 3437
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib261
  article-title: Transcriptional repression of the ovine follicle-stimulating hormone-β gene by 17β-estradiol
  publication-title: Endocrinology
  doi: 10.1210/endo.137.8.8754772
– volume: 128
  start-page: 147
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib122
  article-title: Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function
  publication-title: Development
  doi: 10.1242/dev.128.2.147
– volume: 88
  start-page: 225
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib217
  article-title: Foxl2 function in ovarian development
  publication-title: Mol Genet Metab
  doi: 10.1016/j.ymgme.2006.03.005
– volume: 72
  start-page: 1286
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib22
  article-title: The importance of signal pattern in the transmission of endocrine information: pituitary gonadotropin responses to continuous and pulsatile gonadotropin-releasing hormone
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jcem-72-6-1286
– volume: 143
  start-page: 2839
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib119
  article-title: Regulation of prolactin, GH, and Pit-1 gene expression in anterior pituitary by Pitx2: an approach using Pitx2 mutants
  publication-title: Endocrinology
  doi: 10.1210/endo.143.8.8962
– volume: 83
  start-page: 466
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib10
  article-title: Clinical and hormonal features of selective follicle-stimulating hormone (FSH) deficiency due to FSH β-subunit gene mutations in both sexes
  publication-title: Fertil Steril
  doi: 10.1016/j.fertnstert.2004.06.069
– volume: 74
  start-page: 993
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib18
  article-title: Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.105.049049
– volume: 83
  start-page: 851
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib45
  article-title: A two-site chemiluminescent assay for activin-free follistatin reveals that most follistatin circulating in men and normal cycling women is in an activin-bound state
  publication-title: J Clin Endocrinol Metab
– volume: 118
  start-page: 1148
  year: 1986
  ident: 10.1016/j.fertnstert.2010.03.034_bib81
  article-title: Gonadotropin-releasing hormone stimulates mass changes in phosphoinositides and diacylglycerol accumulation in purified gonadotrope cell cultures
  publication-title: Endocrinology
  doi: 10.1210/endo-118-3-1148
– volume: 269
  start-page: 532
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib193
  article-title: Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)
  publication-title: Science
  doi: 10.1126/science.7624775
– volume: 278
  start-page: 41779
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib257
  article-title: Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-β action
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M305350200
– volume: 23
  start-page: 1001
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib212
  article-title: A novel role for the forkhead transcription factor FOXL2 in activin A–regulated follicle-stimulating hormone β subunit transcription
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2008-0324
– volume: 145
  start-page: 2228
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib165
  article-title: Extracellular signal–regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone–stimulated activity of the glycoprotein hormone follicle-stimulating hormone β-subunit promoter
  publication-title: Endocrinology
  doi: 10.1210/en.2003-1418
– volume: 15
  start-page: 205
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib7
  article-title: Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility
  publication-title: Nat Genet
  doi: 10.1038/ng0297-205
– volume: 13
  start-page: 2212
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib147
  article-title: Differential activation of pituitary hormone genes by human Lhx3 isoforms with distinct DNA binding properties
  publication-title: Mol Endocrinol
  doi: 10.1210/mend.13.12.0395
– volume: 128
  start-page: 509
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib162
  article-title: A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo
  publication-title: Endocrinology
  doi: 10.1210/endo-128-1-509
– volume: 133
  start-page: 277
  year: 1993
  ident: 10.1016/j.fertnstert.2010.03.034_bib250
  article-title: RU486 blocks the effects of inhibin antiserum or luteinizing hormone on the secondary follicle-stimulating hormone surge
  publication-title: Endocrinology
  doi: 10.1210/endo.133.1.8319576
– volume: 142
  start-page: 2267
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib180
  article-title: Transcriptional regulation of the ovine follicle-stimulating hormone–β gene by activin and gonadotropin-releasing hormone (GnRH): involvement of two proximal activator protein-1 sites for GnRH stimulation
  publication-title: Endocrinology
  doi: 10.1210/endo.142.6.8203
– volume: 282
  start-page: 2
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib218
  article-title: The mutations and potential targets of the forkhead transcription factor FOXL2
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2007.11.006
– volume: 146
  start-page: 4340
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib191
  article-title: Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse
  publication-title: Endocrinology
  doi: 10.1210/en.2005-0490
– volume: 502
  start-page: 21
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib173
  article-title: Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway
  publication-title: FEBS Lett
  doi: 10.1016/S0014-5793(01)02651-5
– volume: 190
  start-page: 837
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib190
  article-title: Differential expression and regulation of progesterone receptor isoforms in rat and mouse pituitary cells and LβT2 gonadotropes
  publication-title: J Endocrinol
  doi: 10.1677/joe.1.06923
– volume: 149
  start-page: 1091
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib189
  article-title: Synergistic induction of follicle-stimulating hormone β-subunit gene expression by gonadal steroid hormone receptors and Smad proteins
  publication-title: Endocrinology
  doi: 10.1210/en.2007-1498
– volume: 77
  start-page: 298
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib254
  article-title: Regulation of follicle-stimulating hormone secretion by the interactions of activin-A, dexamethasone and testosterone in anterior pituitary cell cultures of male rats
  publication-title: Neuroendocrinology
  doi: 10.1159/000070896
– volume: 36
  start-page: 201
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib207
  article-title: Acute regulation of murine follicle-stimulating hormone β subunit transcription by activin A
  publication-title: J Mol Endocrinol
  doi: 10.1677/jme.1.01961
– volume: 19
  start-page: 2567
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib128
  article-title: Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone β gene transcription
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.19.4.2567
– volume: 51
  start-page: 123
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib34
  article-title: Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development
  publication-title: Recent Prog Horm Res
– volume: 196
  start-page: 53
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib117
  article-title: Domains of Pit-1 required for transcriptional synergy with GATA-2 on the TSH β gene
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/S0303-7207(02)00223-X
– volume: 44
  start-page: 1
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib23
  article-title: Chemical and biological characterization of the inhibin family of protein hormones
  publication-title: Recent Prog Horm Res
– volume: 19
  start-page: 1893
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib134
  article-title: PITX genes are required for cell survival and Lhx3 activation
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2005-0052
– volume: 943
  start-page: 34
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib52
  article-title: Inhibin, activin, and follistatin in human fetal pituitary and gonadal physiology
  publication-title: Ann N Y Acad Sci
  doi: 10.1111/j.1749-6632.2001.tb03788.x
– volume: 30
  start-page: 67
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib63
  article-title: Kisspeptin and the regulation of the hypothalamic-pituitary-gonadal axis in the rhesus monkey (Macaca mulatta)
  publication-title: Peptides
  doi: 10.1016/j.peptides.2008.06.029
– volume: 82
  start-page: 8203
  year: 1985
  ident: 10.1016/j.fertnstert.2010.03.034_bib99
  article-title: Characterization of pituitary calcium-activated, phospholipid-dependent protein kinase: redistribution by gonadotropin-releasing hormone
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.82.23.8203
– volume: 129
  start-page: 329
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib142
  article-title: Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification
  publication-title: Development
  doi: 10.1242/dev.129.2.329
– volume: 239
  start-page: 1296
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib272
  article-title: Dynamic changes in inhibin messenger RNAs in rat ovarian follicles during the reproductive cycle
  publication-title: Science
  doi: 10.1126/science.3125611
– volume: 194
  start-page: 413
  year: 1993
  ident: 10.1016/j.fertnstert.2010.03.034_bib255
  article-title: Interaction of activin A and gonadal steroids on FSH secretion from primary cultured rat anterior pituitary cells
  publication-title: Biochem Biophys Res Commun
  doi: 10.1006/bbrc.1993.1835
– volume: 61
  start-page: 463
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib101
  article-title: The differential secretion of FSH and LH: regulation through genes, feedback and packaging
  publication-title: Reprod Suppl
– volume: 9
  start-page: 478
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib123
  article-title: The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus
  publication-title: Mol Endocrinol
– volume: 196
  start-page: 497
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib75
  article-title: Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LβT2 gonadotrophs
  publication-title: J Endocrinol
  doi: 10.1677/JOE-07-0542
– volume: 18
  start-page: 925
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib236
  article-title: Androgen regulates follicle-stimulating hormone β gene expression in an activin-dependent manner in immortalized gonadotropes
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2003-0115
– volume: 374
  start-page: 356
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib43
  article-title: Different phenotypes for mice deficient in either activins or activin receptor type II
  publication-title: Nature
  doi: 10.1038/374356a0
– volume: 145
  start-page: 5832
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib107
  article-title: Rapid, efficient isolation of murine gonadotropes and their use in revealing control of follicle-stimulating hormone by paracrine pituitary factors
  publication-title: Endocrinology
  doi: 10.1210/en.2004-0257
– volume: 79
  start-page: 947
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib164
  article-title: Regulation of intracellular signaling cascades by GNRH pulse frequency in the rat pituitary: roles for CaMK II, ERK, and JNK activation
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.108.070987
– volume: 281
  start-page: 27
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib137
  article-title: Smad3 and Pitx2 cooperate in stimulation of FSHβ gene transcription
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2007.10.003
– volume: 123
  start-page: 2946
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib270
  article-title: Follicle-stimulating hormone β subunit messenger ribonucleic acid concentrations during the rat estrous cycle
  publication-title: Endocrinology
  doi: 10.1210/endo-123-6-2946
– volume: 142
  start-page: 2260
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib179
  article-title: The promoter for the ovine follicle-stimulating hormone–β gene (FSHβ) confers FSHβ-like expression on luciferase in transgenic mice: regulatory studies in vivo and in vitro
  publication-title: Endocrinology
  doi: 10.1210/endo.142.6.8202
– volume: 3
  start-page: 474
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib263
  article-title: Divergent effects of estradiol on gonadotropin gene transcription in pituitary fragments
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-3-3-474
– volume: 21
  start-page: 1175
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib194
  article-title: Pulse sensitivity of the luteinizing hormone β promoter is determined by a negative feedback loop involving early growth response-1 and Ngfi-A binding protein 1 and 2
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2006-0392
– volume: 1
  start-page: 849
  year: 1987
  ident: 10.1016/j.fertnstert.2010.03.034_bib28
  article-title: Structural characterization of follistatin: a novel follicle-stimulating hormone release-inhibiting polypeptide from the gonad
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-1-11-849
– volume: 15
  start-page: 77
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib121
  article-title: Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone β subunit transcription
  publication-title: Mol Hum Reprod
  doi: 10.1093/molehr/gan079
– volume: 24
  start-page: 9383
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib204
  article-title: ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.24.21.9383-9389.2004
– volume: 7
  start-page: 668
  year: 1993
  ident: 10.1016/j.fertnstert.2010.03.034_bib210
  article-title: Decay of follicle-stimulating hormone–β messenger RNA in the presence of transcriptional inhibitors and/or inhibin, activin, or follistatin
  publication-title: Mol Endocrinol
– volume: 284
  start-page: 7631
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib222
  article-title: FoxL2 and Smad3 coordinately regulate follistatin gene transcription
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M806676200
– volume: 159
  start-page: 103
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib246
  article-title: Regulation of gonadotrophin secretion by inhibin, testosterone and gonadotrophin-releasing hormone in pituitary cell cultures of male monkeys
  publication-title: J Endocrinol
  doi: 10.1677/joe.0.1590103
– volume: 249
  start-page: 557
  year: 1986
  ident: 10.1016/j.fertnstert.2010.03.034_bib96
  article-title: Gonadotropin release and redistribution of calcium-activated, phospholipid-dependent protein kinase in phorbol-stimulated rat pituitary cells
  publication-title: Arch Biochem Biophys
  doi: 10.1016/0003-9861(86)90033-0
– volume: 45
  start-page: 377
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib220
  article-title: Foxl2 gene and the development of the ovary: a story about goat, mouse, fish and woman
  publication-title: Reprod Nutr Dev
  doi: 10.1051/rnd:2005028
– volume: 247
  start-page: 103
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib229
  article-title: Gonadotroph-specific expression of the human follicle stimulating hormone β gene in transgenic mice
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2005.12.006
– volume: 81
  start-page: 488
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib68
  article-title: Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1)
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.108.075259
– volume: 149
  start-page: 139
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib174
  article-title: Pulsatile gonadotropin-releasing hormone stimulation of gonadotropin subunit transcription in rat pituitaries: evidence for the involvement of Jun N-terminal kinase but not p38
  publication-title: Endocrinology
  doi: 10.1210/en.2007-1113
– volume: 83
  start-page: 851
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib251
  article-title: Steroid hormone receptors: many actors in search of a plot
  publication-title: Cell
  doi: 10.1016/0092-8674(95)90201-5
– volume: 130
  start-page: 3567
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib86
  article-title: Dependence of gonadotropin-releasing hormone-stimulated luteinizing hormone release upon intracellular Ca2+ pools is revealed by desensitization and thapsigargin blockade
  publication-title: Endocrinology
  doi: 10.1210/endo.130.6.1534542
– volume: 182
  start-page: 1408
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib51
  article-title: Effects of activin A and somatostatin on intact FSH secretion and intracellular Ca2+ concentration in human FSH-secreting pituitary adenoma cells
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/0006-291X(92)91890-3
– volume: 293
  start-page: E277
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib239
  article-title: The regulation of FSHβ transcription by gonadal steroids: testosterone and estradiol modulation of the activin intracellular signaling pathway
  publication-title: Am J Physiol Endocrinol Metab
  doi: 10.1152/ajpendo.00447.2006
– volume: 2
  start-page: 512
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib87
  article-title: Gonadotropin-releasing hormone-induced rise in cytosolic free Ca2+ levels: mobilization of cellular and extracellular Ca2+ pools and relationship to gonadotropin secretion
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-2-6-512
– volume: 149
  start-page: 20
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib67
  article-title: Pituitary gonadotroph estrogen receptor-alpha is necessary for fertility in females
  publication-title: Endocrinology
  doi: 10.1210/en.2007-1084
– volume: 22
  start-page: 1908
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib181
  article-title: A composite element that binds basic helix loop helix and basic leucine zipper transcription factors is important for gonadotropin-releasing hormone regulation of the follicle-stimulating hormone β gene
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2007-0455
– volume: 23
  start-page: 2160
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib277
  article-title: FSHB promoter polymorphism within evolutionary conserved element is associated with serum FSH level in men
  publication-title: Hum Reprod
  doi: 10.1093/humrep/den216
– volume: 46
  start-page: 117
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib62
  article-title: GPR54 and kisspeptins
  publication-title: Results Probl Cell Differ
  doi: 10.1007/400_2007_050
– volume: 14
  start-page: 5592
  year: 1994
  ident: 10.1016/j.fertnstert.2010.03.034_bib149
  article-title: GATA-binding proteins regulate the human gonadotropin alpha-subunit gene in the placenta and pituitary gland
  publication-title: Mol Cell Biol
– volume: 4
  start-page: 52
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib202
  article-title: Activin B can signal through both ALK4 and ALK7 in gonadotrope cells
  publication-title: Reprod Biol Endocrinol
  doi: 10.1186/1477-7827-4-52
– volume: 94
  start-page: 585
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib215
  article-title: Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-β signaling
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)81600-1
– volume: 68
  start-page: 397
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib242
  article-title: Testosterone administration inhibits gonadotropin secretion by an effect directly on the human pituitary
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jcem-68-2-397
– volume: 149
  start-page: 3095
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib136
  article-title: Paired-like homeodomain transcription factors 1 and 2 regulate follicle-stimulating hormone β-subunit transcription through a conserved cis-element
  publication-title: Endocrinology
  doi: 10.1210/en.2007-0425
– volume: 137
  start-page: 85
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib248
  article-title: Mechanism of the inhibitory action of RU486 on the secondary follicle-stimulating hormone surge
  publication-title: Endocrinology
  doi: 10.1210/endo.137.1.8536646
– volume: 5
  start-page: 949
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib85
  article-title: Spontaneous and agonist-induced calcium oscillations in pituitary gonadotrophs
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-5-7-949
– volume: 145
  start-page: 387
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib100
  article-title: Gonadotrophin secretion revisited. How many ways can FSH leave a gonadotroph?
  publication-title: J Endocrinol
  doi: 10.1677/joe.0.1450387
– volume: 145
  start-page: 4866
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib132
  article-title: Regulation of the follicle-stimulating hormone β gene by the LHX3 LIM-homeodomain transcription factor
  publication-title: Endocrinology
  doi: 10.1210/en.2004-0598
– volume: 139
  start-page: 469
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib36
  article-title: Activin: an endocrine or paracrine agent?
  publication-title: Eur J Endocrinol
  doi: 10.1530/eje.0.1390469
– volume: 6
  start-page: 81
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib227
  article-title: Gonadotrope-specific expression of the human follicle-stimulating hormone β-subunit gene in pituitaries of transgenic mice
  publication-title: Mol Endocrinol
– volume: 425
  start-page: 577
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib223
  article-title: Smad-dependent and Smad-independent pathways in TGF-β family signalling
  publication-title: Nature
  doi: 10.1038/nature02006
– volume: 154
  start-page: 398
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib89
  article-title: Biphasic activation of cytosolic free calcium and LH responses by gonadotropin-releasing hormone
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/0006-291X(88)90699-7
– volume: 104
  start-page: 31
  year: 1993
  ident: 10.1016/j.fertnstert.2010.03.034_bib19
  article-title: GnRH pulses—the regulators of human reproduction
  publication-title: Trans Am Clin Climatol Assoc
– volume: 13
  start-page: 1497
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib130
  article-title: The equine luteinizing hormone β-subunit promoter contains two functional steroidogenic factor-1 response elements
  publication-title: Mol Endocrinol
– volume: 144
  start-page: 1802
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib157
  article-title: Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L β T2 cells: role of GnRH receptor concentration
  publication-title: Endocrinology
  doi: 10.1210/en.2002-221140
– volume: 139
  start-page: 4455
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib175
  article-title: Transcriptional activation of the ovine follicle-stimulating hormone β-subunit gene by gonadotropin-releasing hormone: involvement of two activating protein-1–binding sites and protein kinase C
  publication-title: Endocrinology
  doi: 10.1210/endo.139.11.6281
– volume: 128
  start-page: 1682
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib38
  article-title: Evidence for an autocrine role of activin B within rat anterior pituitary cultures
  publication-title: Endocrinology
  doi: 10.1210/endo-128-3-1682
– volume: 360
  start-page: 2742
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib16
  article-title: Isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa0900136
– volume: 62
  start-page: 58
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib226
  article-title: Inhibition of transforming growth factor (TGF)-β1–induced extracellular matrix with a novel inhibitor of the TGF-β type I receptor kinase activity: SB-431542
  publication-title: Mol Pharmacol
  doi: 10.1124/mol.62.1.58
– volume: 79
  start-page: 434
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib12
  article-title: Isolated follicle-stimulating hormone (FSH) deficiency in a young man with normal virilization who did not have mutations in the FSHβ gene
  publication-title: Fertil Steril
  doi: 10.1016/S0015-0282(02)04682-4
– volume: 3
  start-page: 131
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib49
  article-title: Localization of inhibin/activin subunits in normal pituitary and in pituitary adenomas
  publication-title: Pituitary
  doi: 10.1023/A:1011431123208
– volume: 19
  start-page: 2610
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib216
  article-title: Activin regulates luteinizing hormone β-subunit gene expression through Smad-binding and homeobox elements
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2005-0047
– volume: 273
  start-page: 14712
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib125
  article-title: Steroidogenic factor-1 and early growth response protein 1 act through two composite DNA binding sites to regulate luteinizing hormone β-subunit gene expression
  publication-title: J Biol Chem
  doi: 10.1074/jbc.273.24.14712
– volume: 73
  start-page: 609
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib241
  article-title: Sex steroid control of gonadotropin secretion in the human male. I. Effects of testosterone administration in normal and gonadotropin-releasing hormone–deficient men
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jcem-73-3-609
– volume: 136
  start-page: 1049
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib235
  article-title: The 5′-flanking region of the ovine follicle-stimulating hormone–β gene contains six progesterone response elements: three proximal elements are sufficient to increase transcription in the presence of progesterone
  publication-title: Endocrinology
  doi: 10.1210/endo.136.3.7867558
– volume: 36
  start-page: 663
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib11
  article-title: Follitropin (FSH) deficiency in an infertile male due to FSHβ gene mutation. A syndrome of normal puberty and virilization but underdeveloped testicles with azoospermia, low FSH but high lutropin and normal serum testosterone concentrations
  publication-title: Clin Chem Lab Med
  doi: 10.1515/CCLM.1998.118
– volume: 173
  start-page: 1
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib152
  article-title: Signalling, cycling and desensitisation of gonadotrophin-releasing hormone receptors
  publication-title: J Endocrinol
  doi: 10.1677/joe.0.1730001
– volume: 143
  start-page: 1651
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib169
  article-title: Transcriptional activation of the ovine follicle-stimulating hormone–β gene by gonadotropin-releasing hormone involves multiple signal transduction pathways
  publication-title: Endocrinology
  doi: 10.1210/endo.143.5.8771
– volume: 125
  start-page: 2787
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib58
  article-title: Recombinant human activin-A stimulates basal FSH and GnRH-stimulated FSH and LH release in the adult male macaque, Macaca fascicularis
  publication-title: Endocrinology
  doi: 10.1210/endo-125-5-2787
– volume: 13
  start-page: 1338
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib186
  article-title: Estradiol suppresses phosphorylation of cyclic adenosine 3′,5′-monophosphate response element binding protein (CREB) in the pituitary: evidence for indirect action via gonadotropin-releasing hormone
  publication-title: Mol Endocrinol
– volume: 138
  start-page: 2286
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib249
  article-title: The antiprogestins RU486 and ZK98299 affect follicle-stimulating hormone secretion differentially on estrus, but not on proestrus
  publication-title: Endocrinology
  doi: 10.1210/endo.138.6.5161
– volume: 273
  start-page: 16
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib266
  article-title: Estrogen receptor signaling is an unstable feature of the gonadotropic LβT2 cell line
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2007.04.009
– volume: 36
  start-page: 339
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib53
  article-title: Age related changes in follicle stimulating hormone, luteinizing hormone, oestradiol and immunoreactive inhibin in women of reproductive age
  publication-title: Clin Endocrinol (Oxf)
  doi: 10.1111/j.1365-2265.1992.tb01457.x
– volume: 142
  start-page: 139
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib185
  article-title: Regulation of gonadotropin subunit gene transcription by gonadotropin-releasing hormone: measurement of primary transcript ribonucleic acids by quantitative reverse transcription–polymerase chain reaction assays
  publication-title: Endocrinology
  doi: 10.1210/endo.142.1.7881
– volume: 141
  start-page: 4295
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib5
  article-title: Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mice
  publication-title: Endocrinology
  doi: 10.1210/endo.141.11.7765
– volume: 142
  start-page: 2284
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib41
  article-title: Cell-specific transcriptional regulation of follicle-stimulating hormone-β by activin and gonadotropin-releasing hormone in the LβT2 pituitary gonadotrope cell model
  publication-title: Endocrinology
  doi: 10.1210/endo.142.6.8185
– volume: 138
  start-page: 2621
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib176
  article-title: Two proximal activating protein-1–binding sites are sufficient to stimulate transcription of the ovine follicle-stimulating hormone–β gene
  publication-title: Endocrinology
  doi: 10.1210/endo.138.6.5205
– volume: 234
  start-page: 1366
  year: 1986
  ident: 10.1016/j.fertnstert.2010.03.034_bib14
  article-title: A deletion truncating the gonadotropin-releasing hormone gene is responsible for hypogonadism in the hpg mouse
  publication-title: Science
  doi: 10.1126/science.3024317
– volume: 191
  start-page: 309
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib264
  article-title: The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-alpha
  publication-title: J Endocrinol
  doi: 10.1677/joe.1.06965
– volume: 138
  start-page: 2841
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib47
  article-title: Pituitary follistatin regulates activin-mediated production of follicle-stimulating hormone during the rat estrous cycle
  publication-title: Endocrinology
  doi: 10.1210/endo.138.7.5279
– volume: 36
  start-page: 591
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib200
  article-title: Cell-specificity of transforming growth factor-β response is dictated by receptor bioavailability
  publication-title: J Mol Endocrinol
  doi: 10.1677/jme.1.01936
– volume: 186
  start-page: 109
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib72
  article-title: BMP-4 inhibits follicle-stimulating hormone secretion in ewe pituitary
  publication-title: J Endocrinol
  doi: 10.1677/joe.1.05988
– volume: 86
  start-page: 4501
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib98
  article-title: Induction of exocytosis in permeabilized pituitary cells by alpha- and β-type protein kinase C
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.86.12.4501
– volume: 124
  start-page: 2193
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib271
  article-title: Decreased inhibin gene expression in preovulatory follicles requires primary gonadotropin surges
  publication-title: Endocrinology
  doi: 10.1210/endo-124-5-2193
– volume: 13
  start-page: 484
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib143
  article-title: Role of the bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development
  publication-title: Genes Dev
  doi: 10.1101/gad.13.4.484
– volume: 260
  start-page: 82
  year: 1993
  ident: 10.1016/j.fertnstert.2010.03.034_bib91
  article-title: Rhythmic exocytosis stimulated by GnRH-induced calcium oscillations in rat gonadotropes
  publication-title: Science
  doi: 10.1126/science.8385366
– volume: 83
  start-page: 3302
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib54
  article-title: Net increase in stimulatory input resulting from a decrease in inhibin B and an increase in activin A may contribute in part to the rise in follicular phase follicle-stimulating hormone of aging cycling women
  publication-title: J Clin Endocrinol Metab
– volume: 279
  start-page: 152
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib167
  article-title: A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone β gene by gonadotropin-releasing hormone
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M304697200
– volume: 8
  start-page: 2302
  year: 1994
  ident: 10.1016/j.fertnstert.2010.03.034_bib120
  article-title: The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis
  publication-title: Genes Dev
  doi: 10.1101/gad.8.19.2302
– volume: 27
  start-page: 4105
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib192
  article-title: Distinct mechanisms involving diverse histone deacetylases repress expression of the two gonadotropin β-subunit genes in immature gonadotropes, and their actions are overcome by gonadotropin-releasing hormone
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.00248-07
– volume: 206
  start-page: 93
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib221
  article-title: The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/S0303-7207(03)00235-1
– volume: 139
  start-page: 2223
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib256
  article-title: Antiprogestins suppress basal and activin-stimulated follicle-stimulating hormone secretion in an estrogen-dependent manner
  publication-title: Endocrinology
  doi: 10.1210/endo.139.5.6015
– volume: 42
  start-page: 1117
  year: 1994
  ident: 10.1016/j.fertnstert.2010.03.034_bib110
  article-title: In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development
  publication-title: J Histochem Cytochem
  doi: 10.1177/42.8.8027530
– volume: 20
  start-page: 6127
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib33
  article-title: Activin βC and βE genes are not essential for mouse liver growth, differentiation, and regeneration
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.20.16.6127-6137.2000
– volume: 15
  start-page: 216
  year: 1994
  ident: 10.1016/j.fertnstert.2010.03.034_bib243
  article-title: FSH is produced by GnRH-deficient men and is suppressed by testosterone
  publication-title: J Androl
  doi: 10.1002/j.1939-4640.1994.tb00435.x
– volume: 142
  start-page: 2275
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib74
  article-title: A novel role for bone morphogenetic proteins in the synthesis of follicle-stimulating hormone
  publication-title: Endocrinology
  doi: 10.1210/endo.142.6.8159
– volume: 32
  start-page: 391
  year: 1985
  ident: 10.1016/j.fertnstert.2010.03.034_bib269
  article-title: Effect of gonadotropin-releasing hormone antagonists on serum follicle-stimulating hormone and luteinizing hormone under conditions of singular follicle-stimulating hormone secretion
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod32.2.391
– volume: 149
  start-page: 133
  year: 1987
  ident: 10.1016/j.fertnstert.2010.03.034_bib29
  article-title: Follistatin specifically inhibits pituitary follicle stimulating hormone release in vitro
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/0006-291X(87)91614-7
– volume: 64
  start-page: 714
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib37
  article-title: Activin modulates differential effects of estradiol on synthesis and secretion of follicle-stimulating hormone in ovine pituitary cells
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod64.2.714
– volume: 143
  start-page: 4938
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib76
  article-title: A novel function of bone morphogenetic protein-15 in the pituitary: selective synthesis and secretion of FSH by gonadotropes
  publication-title: Endocrinology
  doi: 10.1210/en.2002-220929
– volume: 87
  start-page: 3702
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib8
  article-title: FSH β gene mutations in a female with partial breast development and a male sibling with normal puberty and azoospermia
  publication-title: J Clin Endocrinol Metab
– volume: 19
  start-page: 1849
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib205
  article-title: Smad3 mediates activin-induced transcription of follicle-stimulating hormone β-subunit gene
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2004-0475
– volume: 12
  start-page: 844
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib203
  article-title: The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse
  publication-title: Genes Dev
  doi: 10.1101/gad.12.6.844
– volume: 20
  start-page: 2062
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib188
  article-title: Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone β-subunit gene expression at the level of the gonadotrope
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2005-0316
– volume: 28
  start-page: 2662
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib31
  article-title: The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
  publication-title: EMBO J
  doi: 10.1038/emboj.2009.205
– volume: 255
  start-page: 462
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib90
  article-title: GnRH-induced Ca2+ oscillations and rhythmic hyperpolarizations of pituitary gonadotropes
  publication-title: Science
  doi: 10.1126/science.1734523
– volume: 72
  start-page: 1261
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib50
  article-title: The effects of activin on follicle-stimulating hormone secretion and biosynthesis in human glycoprotein hormone-producing pituitary adenomas
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jcem-72-6-1261
– volume: 28
  start-page: 167
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib276
  article-title: Cre-mediated recombination in the pituitary gland
  publication-title: Genesis
  doi: 10.1002/1526-968X(200011/12)28:3/4<167::AID-GENE120>3.0.CO;2-N
– volume: 97
  start-page: 587
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib148
  article-title: Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80770-9
– volume: 162
  start-page: R1
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib114
  article-title: LβT2 gonadotroph cells secrete follicle stimulating hormone (FSH) in response to activin A
  publication-title: J Endocrinol
  doi: 10.1677/joe.0.162r001
– volume: 261
  start-page: 12506
  year: 1986
  ident: 10.1016/j.fertnstert.2010.03.034_bib84
  article-title: Gonadotropin-releasing hormone activates a rapid Ca2+-independent phosphodiester hydrolysis of polyphosphoinositides in pituitary gonadotrophs
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(18)67116-9
– volume: 260
  start-page: 3243
  year: 1985
  ident: 10.1016/j.fertnstert.2010.03.034_bib95
  article-title: Hormone-induced redistribution of calcium-activated phospholipid-dependent protein kinase in pituitary gonadotrophs
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(19)83610-4
– volume: 8
  start-page: 414
  year: 1994
  ident: 10.1016/j.fertnstert.2010.03.034_bib42
  article-title: Activin/inhibin β B subunit gene disruption leads to defects in eyelid development and female reproduction
  publication-title: Genes Dev
  doi: 10.1101/gad.8.4.414
– volume: 125
  start-page: 917
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib160
  article-title: The frequency of gonadotropin-releasing-hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression
  publication-title: Endocrinology
  doi: 10.1210/endo-125-2-917
– volume: 104
  start-page: 849
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib115
  article-title: A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins
  publication-title: Cell
  doi: 10.1016/S0092-8674(01)00282-3
– volume: 272
  start-page: 13835
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib32
  article-title: A novel role of follistatin, an activin-binding protein, in the inhibition of activin action in rat pituitary cells. Endocytotic degradation of activin and its acceleration by follistatin associated with cell-surface heparan sulfate
  publication-title: J Biol Chem
  doi: 10.1074/jbc.272.21.13835
– volume: 122
  start-page: 3319
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib113
  article-title: Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice
  publication-title: Development
  doi: 10.1242/dev.122.10.3319
– volume: 51
  start-page: 23
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib105
  article-title: The gonadotropin genes: evolution of distinct mechanisms for hormonal control
  publication-title: Recent Prog Horm Res
– volume: 72
  start-page: 523
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib233
  article-title: Testosterone stimulates follicle-stimulating hormone β transcription via activation of extracellular signal-regulated kinase: evidence in rat pituitary cells
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.104.035196
– volume: 146
  start-page: 4814
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib224
  article-title: Transforming growth factor β–activated kinase 1 is a key mediator of ovine follicle-stimulating hormone β-subunit expression
  publication-title: Endocrinology
  doi: 10.1210/en.2005-0457
– volume: 81
  start-page: 3328
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib46
  article-title: Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy
  publication-title: J Clin Endocrinol Metab
– volume: 127
  start-page: 2869
  year: 1990
  ident: 10.1016/j.fertnstert.2010.03.034_bib161
  article-title: Differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone pulse amplitude in female rats
  publication-title: Endocrinology
  doi: 10.1210/endo-127-6-2869
– volume: 21
  start-page: 3071
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib166
  article-title: p38 mitogen-activated protein kinase is critical for synergistic induction of the FSH(β) gene by gonadotropin-releasing hormone and activin through augmentation of c-Fos induction and Smad phosphorylation
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2007-0247
– volume: 78
  start-page: 752
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib71
  article-title: Weaning and the developmental changes in follicle-stimulating hormone, pituitary adenylate cyclase-activating polypeptide, and inhibin B in the male rat
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.107.065466
– volume: 30
  start-page: 57
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib64
  article-title: Kisspeptins and the control of gonadotropin secretion in male and female rodents
  publication-title: Peptides
  doi: 10.1016/j.peptides.2008.08.009
– volume: 61
  start-page: 628
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib240
  article-title: Hormonal regulation of human follicle-stimulating hormone–β subunit gene expression: GnRH stimulation and GnRH-independent androgen inhibition
  publication-title: Neuroendocrinology
  doi: 10.1159/000126889
– volume: 15
  start-page: 201
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib4
  article-title: Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility
  publication-title: Nat Genet
  doi: 10.1038/ng0297-201
– volume: 95
  start-page: 13612
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib6
  article-title: Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.95.23.13612
– volume: 71
  start-page: 277
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib129
  article-title: Transcriptional properties of Ptx1 and Ptx2 isoforms
  publication-title: Neuroendocrinology
  doi: 10.1159/000054547
– volume: 3
  start-page: 1969
  year: 1989
  ident: 10.1016/j.fertnstert.2010.03.034_bib196
  article-title: Inhibin, activin, and follistatin: regulation of follicle-stimulating hormone messenger ribonucleic acid levels
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-3-12-1969
– volume: 38
  start-page: 315
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib40
  article-title: Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone β subunit transcription
  publication-title: J Mol Endocrinol
  doi: 10.1677/jme.1.02196
– volume: 128
  start-page: 13
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib245
  article-title: Intra-pituitary regulation of gonadotrophs in male rodents and primates
  publication-title: Reproduction
  doi: 10.1530/rep.1.00195
– volume: 90
  start-page: 826
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib57
  article-title: Relationship of estradiol and inhibin to the follicle-stimulating hormone variability in hypergonadotropic hypogonadism or premature ovarian failure
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2004-1319
– year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib177
  article-title: Gonadotropin releasing hormone-mediated phosphorylation of estrogen receptor α contributes to fosB expression in mouse gonadotrophs
  publication-title: Endocrinology
  doi: 10.1210/en.2009-0455
– volume: 149
  start-page: 2701
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib108
  article-title: Functional characterization of genetically labeled gonadotropes
  publication-title: Endocrinology
  doi: 10.1210/en.2007-1502
– volume: 148
  start-page: 4500
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib214
  article-title: Expression and regulation of the β-subunit of ovine follicle-stimulating hormone relies heavily on a promoter sequence likely to bind Smad-associated proteins
  publication-title: Endocrinology
  doi: 10.1210/en.2006-1635
– volume: 404
  start-page: 411
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib27
  article-title: β-Glycan binds inhibin and can mediate functional antagonism of activin signalling
  publication-title: Nature
  doi: 10.1038/35006129
– volume: 18
  start-page: 1158
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib208
  article-title: Activin regulation of the follicle-stimulating hormone β-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2003-0442
– volume: 2
  start-page: 653
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib219
  article-title: Premature ovarian failure and forkhead transcription factor FOXL2: blepharophimosis–ptosis–epicanthus inversus syndrome and ovarian dysfunction
  publication-title: Pediatr Endocrinol Rev
– volume: 50
  start-page: 888
  year: 1994
  ident: 10.1016/j.fertnstert.2010.03.034_bib59
  article-title: Systemic and intraluteal infusion of inhibin A or activin A in rhesus monkeys during the luteal phase of the menstrual cycle
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod50.4.888
– volume: 274
  start-page: 26563
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib172
  article-title: Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus
  publication-title: J Biol Chem
  doi: 10.1074/jbc.274.37.26563
– volume: 9
  start-page: 535
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib30
  article-title: The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding
  publication-title: Dev Cell
  doi: 10.1016/j.devcel.2005.09.008
– volume: 77
  start-page: 241
  year: 1993
  ident: 10.1016/j.fertnstert.2010.03.034_bib60
  article-title: Human recombinant activin-A alters pituitary luteinizing hormone and follicle-stimulating hormone secretion, follicular development, and steroidogenesis, during the menstrual cycle in rhesus monkeys
  publication-title: J Clin Endocrinol Metab
– volume: 14
  start-page: 1190
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib48
  article-title: Main inhibitor of follicle stimulating hormone in the luteal-follicular transition: inhibin A, oestradiol, or inhibin B?
  publication-title: Hum Reprod
  doi: 10.1093/humrep/14.5.1190
– volume: 124
  start-page: 2807
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib144
  article-title: The bicoid-related homeoprotein Ptx1 defines the most anterior domain of the embryo and differentiates posterior from anterior lateral mesoderm
  publication-title: Development
  doi: 10.1242/dev.124.14.2807
– volume: 81
  start-page: 693
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib13
  article-title: Apparent primary follicle-stimulating hormone deficiency is a rare cause of treatable male infertility
  publication-title: Fertil Steril
  doi: 10.1016/j.fertnstert.2003.07.030
– volume: 67
  start-page: 285
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib265
  article-title: Lessons in estrogen biology from knockout and transgenic animals
  publication-title: Annu Rev Physiol
  doi: 10.1146/annurev.physiol.67.040403.115914
– volume: 149
  start-page: 4168
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib262
  article-title: Estrogen receptor alpha signaling pathways differentially regulate gonadotropin subunit gene expression and serum follicle-stimulating hormone in the female mouse
  publication-title: Endocrinology
  doi: 10.1210/en.2007-1807
– volume: 81
  start-page: 2742
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib55
  article-title: Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles
  publication-title: J Clin Endocrinol Metab
– volume: 137
  start-page: 3667
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib231
  article-title: Gonadotropin-releasing hormone regulates follicle-stimulating hormone–β gene expression through an activin/follistatin autocrine or paracrine loop
  publication-title: Endocrinology
  doi: 10.1210/endo.137.9.8756531
– volume: 274
  start-page: 13870
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib124
  article-title: Activation of luteinizing hormone β gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1
  publication-title: J Biol Chem
  doi: 10.1074/jbc.274.20.13870
– volume: 68
  start-page: 1877
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib199
  article-title: Activin signaling pathways in ovine pituitary and LβT2 gonadotrope cells
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.102.012005
– volume: 26
  start-page: 207
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib1
  article-title: Mutations in human gonadotropin and gonadotropin-receptor genes
  publication-title: Endocrine
  doi: 10.1385/ENDO:26:3:207
– volume: 271
  start-page: 6645
  year: 1996
  ident: 10.1016/j.fertnstert.2010.03.034_bib126
  article-title: Stimulation of luteinizing hormone β gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1
  publication-title: J Biol Chem
  doi: 10.1074/jbc.271.12.6645
– volume: 11
  start-page: 309
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib198
  article-title: Activin signal transduction pathways
  publication-title: Trends Endocrinol Metab
  doi: 10.1016/S1043-2760(00)00294-0
– volume: 16
  start-page: 1840
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib139
  article-title: Pituitary homeobox 1 activates the rat FSHβ (rFSHβ) gene through both direct and indirect interactions with the rFSHβ gene promoter
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2002-0088
– volume: 81
  start-page: 243
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib187
  article-title: Rapid effect of GNRH1 on follicle-stimulating hormone β gene expression in LβT2 mouse pituitary cells requires the progesterone receptor
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.109.076216
– volume: 87
  start-page: 8855
  year: 1990
  ident: 10.1016/j.fertnstert.2010.03.034_bib94
  article-title: Dependence of hormone secretion on activation-inactivation kinetics of voltage-sensitive Ca2+ channels in pituitary gonadotrophs
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.87.22.8855
– volume: 283
  start-page: 11485
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib103
  article-title: A carboxyl-terminal sequence in the lutropin β subunit contributes to the sorting of lutropin to the regulated pathway
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M800654200
– volume: 21
  start-page: 551
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib2
  article-title: Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function
  publication-title: Endocr Rev
  doi: 10.1210/edrv.21.5.0409
– volume: 96
  start-page: 25
  year: 1993
  ident: 10.1016/j.fertnstert.2010.03.034_bib275
  article-title: The FSH β-subunit promoter directs the expression of Herpes simplex virus type 1 thymidine kinase to the testis of transgenic mice
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/0303-7207(93)90091-W
– volume: 25
  start-page: 521
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib104
  article-title: Multiple and overlapping combinatorial codes orchestrate hormonal responsiveness and dictate cell-specific expression of the genes encoding luteinizing hormone
  publication-title: Endocr Rev
  doi: 10.1210/er.2003-0029
– volume: 4
  start-page: 1943
  year: 1990
  ident: 10.1016/j.fertnstert.2010.03.034_bib232
  article-title: Gonadotropin subunit messenger RNA concentrations after blockade of gonadotropin-releasing hormone action: testosterone selectively increases follicle-stimulating hormone β-subunit messenger RNA by posttranscriptional mechanisms
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-4-12-1943
– volume: 148
  start-page: 762
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib206
  article-title: Activin and glucocorticoids synergistically activate follicle-stimulating hormone β-subunit gene expression in the immortalized LβT2 gonadotrope cell line
  publication-title: Endocrinology
  doi: 10.1210/en.2006-0952
– volume: 46
  start-page: 507
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib141
  article-title: Pitx2 deletion in pituitary gonadotropes is compatible with gonadal development, puberty, and fertility
  publication-title: Genesis
  doi: 10.1002/dvg.20398
– volume: 23
  start-page: 1092
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib171
  article-title: ERK signaling in the pituitary is required for female but not male fertility
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2009-0030
– volume: 18
  start-page: 121
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib92
  article-title: Local Ca2+ release from internal stores controls exocytosis in pituitary gonadotrophs
  publication-title: Neuron
  doi: 10.1016/S0896-6273(01)80051-9
– volume: 220
  start-page: 59
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib201
  article-title: Activin isoforms signal through type I receptor serine/threonine kinase ALK7
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2004.03.009
– volume: 225
  start-page: 29
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib25
  article-title: Autocrine/paracrine regulation of pituitary function by activin, inhibin and follistatin
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2004.02.010
– volume: 19
  start-page: 237
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib168
  article-title: Synergy between activin A and gonadotropin-releasing hormone in transcriptional activation of the rat follicle-stimulating hormone–β gene
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2003-0473
– volume: 272
  start-page: 24339
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib116
  article-title: Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin β-subunit promoter
  publication-title: J Biol Chem
  doi: 10.1074/jbc.272.39.24339
– volume: 18
  start-page: 606
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib111
  article-title: Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone β subunit in mouse gonadotrope cells
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2003-0264
– volume: 252
  start-page: 167
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib267
  article-title: Transcription of gonadotropin β subunit genes involves cross-talk between the transcription factors and co-regulators that mediate actions of the regulatory hormones
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2006.03.024
– volume: 2
  start-page: 1237
  year: 1988
  ident: 10.1016/j.fertnstert.2010.03.034_bib35
  article-title: Recombinant expression and characterization of human activin A
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-2-12-1237
– volume: 117
  start-page: 2443
  year: 1985
  ident: 10.1016/j.fertnstert.2010.03.034_bib238
  article-title: Progesterone inhibits basal production of follicle-stimulating hormone in ovine pituitary cell culture
  publication-title: Endocrinology
  doi: 10.1210/endo-117-6-2443
– volume: 8
  start-page: 647
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib159
  article-title: Molecular mechanisms of the regulation of gonadotropin gene expression by gonadotropin-releasing hormone
  publication-title: Mol Cells
  doi: 10.1016/S1016-8478(23)13478-9
– volume: 130
  start-page: 263
  year: 2005
  ident: 10.1016/j.fertnstert.2010.03.034_bib3
  article-title: An update of the pathophysiology of human gonadotrophin subunit and receptor gene mutations and polymorphisms
  publication-title: Reproduction
  doi: 10.1530/rep.1.00663
– volume: 74
  start-page: 600
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib268
  article-title: Hypothalamic gonadotropin-releasing hormone secretion and follicle-stimulating hormone dynamics during the luteal-follicular transition
  publication-title: J Clin Endocrinol Metab
– volume: 262
  start-page: 1166
  year: 1987
  ident: 10.1016/j.fertnstert.2010.03.034_bib83
  article-title: Novel aspects of gonadotropin-releasing hormone action on inositol polyphosphate metabolism in cultured pituitary gonadotrophs
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(19)75766-4
– volume: 170
  start-page: 601
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib234
  article-title: Androgen responsiveness of the pituitary gonadotrope cell line LβT2
  publication-title: J Endocrinol
  doi: 10.1677/joe.0.1700601
– volume: 7
  start-page: 66
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib140
  article-title: Activin A induces ovine follicle stimulating hormone β using −169/−58 bp of its promoter and a simple TATA box
  publication-title: Reprod Biol Endocrinol
  doi: 10.1186/1477-7827-7-66
– volume: 20
  start-page: 2909
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib225
  article-title: Activin modulates the transcriptional response of LβT2 cells to gonadotropin-releasing hormone and alters cellular proliferation
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2006-0109
– volume: 50
  start-page: 680
  year: 1994
  ident: 10.1016/j.fertnstert.2010.03.034_bib20
  article-title: Continuous gonadotropin-releasing hormone infusion stimulates dramatic gonadal development in hypogonadal female mice
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod50.3.680
– volume: 212
  start-page: 19
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib44
  article-title: Regulation of FSHβ and GnRH receptor gene expression in activin receptor II knockout male mice
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2003.09.019
– volume: 32
  start-page: 467
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib102
  article-title: Differential secretion of gonadotrophins: investigation of the role of secretogranin II and chromogranin A in the release of LH and FSH in LβT2 cells
  publication-title: J Mol Endocrinol
  doi: 10.1677/jme.0.0320467
– volume: 37
  start-page: 63
  year: 2006
  ident: 10.1016/j.fertnstert.2010.03.034_bib151
  article-title: A novel technique for temporally regulated cell type-specific Cre expression and recombination in the pituitary gonadotroph
  publication-title: J Mol Endocrinol
  doi: 10.1677/jme.1.02053
– volume: 129
  start-page: 1721
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib209
  article-title: Activin stabilizes follicle-stimulating hormone–β messenger ribonucleic acid levels
  publication-title: Endocrinology
  doi: 10.1210/endo-129-4-1721
– volume: 131
  start-page: 1403
  year: 1992
  ident: 10.1016/j.fertnstert.2010.03.034_bib197
  article-title: Dynamic regulation of follicle-stimulating hormone-β messenger ribonucleic acid levels by activin and gonadotropin-releasing hormone in perifused rat pituitary cells
  publication-title: Endocrinology
  doi: 10.1210/endo.131.3.1505470
– volume: 15
  start-page: 331
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib155
  article-title: Genomics view of gonadotrope signaling circuits
  publication-title: Trends Endocrinol Metab
  doi: 10.1016/j.tem.2004.07.008
– volume: 69
  start-page: 1160
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib56
  article-title: ACE-011, a soluble activin receptor type IIA IgG-Fc fusion protein, decreases follicle stimulating hormone and increases bone-specific alkaline phosphatase, a marker of bone formation, in postmenopausal healthy women
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.SABCS-1160
– volume: 140
  start-page: 2415
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib274
  article-title: The gonadotropin-releasing hormone receptor gene promoter directs pituitary-specific oncogene expression in transgenic mice
  publication-title: Endocrinology
  doi: 10.1210/endo.140.5.6682
– volume: 136
  start-page: 1885
  year: 1995
  ident: 10.1016/j.fertnstert.2010.03.034_bib112
  article-title: Transcriptional activation of the follicle-stimulating hormone β-subunit gene by activin
  publication-title: Endocrinology
  doi: 10.1210/endo.136.5.7720634
– volume: 17
  start-page: 318
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib138
  article-title: Regulation of the rat follicle-stimulating hormone β-subunit promoter by activin
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2002-0081
– volume: 68
  start-page: 1145
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib184
  article-title: CBP and p300: HATs for different occasions
  publication-title: Biochem Pharmacol
  doi: 10.1016/j.bcp.2004.03.045
– volume: 134
  start-page: 861
  year: 1986
  ident: 10.1016/j.fertnstert.2010.03.034_bib82
  article-title: Gonadotropin releasing hormone enhances polyphosphoinositide hydrolysis in rat pituitary cells
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/S0006-291X(86)80499-5
– volume: 15
  start-page: 203
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib65
  article-title: The role of kisspeptin in the control of gonadotrophin secretion
  publication-title: Hum Reprod Update
  doi: 10.1093/humupd/dmn058
– volume: 23
  start-page: 402
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib178
  article-title: GnRH-regulated expression of Jun and JUN target genes in gonadotropes requires a functional interaction between TCF/LEF family members and β-catenin
  publication-title: Mol Endocrinol
  doi: 10.1210/me.2008-0370
– volume: 25
  start-page: 182
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib145
  article-title: Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency
  publication-title: Nat Genet
  doi: 10.1038/76041
– volume: 4
  start-page: 597
  year: 1990
  ident: 10.1016/j.fertnstert.2010.03.034_bib109
  article-title: Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice
  publication-title: Mol Endocrinol
  doi: 10.1210/mend-4-4-597
– volume: 12
  start-page: 428
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib131
  article-title: The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3
  publication-title: Mol Endocrinol
  doi: 10.1210/mend.12.3.0073
– volume: 202
  start-page: 631
  year: 1978
  ident: 10.1016/j.fertnstert.2010.03.034_bib21
  article-title: Hypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormone
  publication-title: Science
  doi: 10.1126/science.100883
– volume: 54
  start-page: 455
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib106
  article-title: Regulation of glycoprotein hormone alpha-subunit gene expression
  publication-title: Recent Prog Horm Res
– volume: 139
  start-page: 3289
  year: 1998
  ident: 10.1016/j.fertnstert.2010.03.034_bib228
  article-title: Genetic rescue of follicle-stimulating hormone β-deficient mice
  publication-title: Endocrinology
  doi: 10.1210/endo.139.7.6111
– volume: 33
  start-page: 559
  year: 2004
  ident: 10.1016/j.fertnstert.2010.03.034_bib156
  article-title: Regulation of gonadotropin subunit gene transcription
  publication-title: J Mol Endocrinol
  doi: 10.1677/jme.1.01600
– volume: 148
  start-page: 1099
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib182
  article-title: Gonadotropin-releasing hormone couples to 3′,5′-cyclic adenosine-5′-monophosphate pathway through novel protein kinase Cdelta and -epsilon in LβT2 gonadotrope cells
  publication-title: Endocrinology
  doi: 10.1210/en.2006-1473
– volume: 203
  start-page: 169
  year: 2003
  ident: 10.1016/j.fertnstert.2010.03.034_bib273
  article-title: Pituitary tumorigenesis targeted by the ovine follicle-stimulating hormone β-subunit gene regulatory region in transgenic mice
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/S0303-7207(02)00430-6
– volume: 25
  start-page: 379
  year: 2007
  ident: 10.1016/j.fertnstert.2010.03.034_bib69
  article-title: Paracrine control of gonadotrophs
  publication-title: Semin Reprod Med
  doi: 10.1055/s-2007-984744
– volume: 113
  start-page: 535
  year: 1983
  ident: 10.1016/j.fertnstert.2010.03.034_bib17
  article-title: The effects of daily administration of single and multiple injections of gonadotropin-releasing hormone on pituitary and gonadal function in the hypogonadal (hpg) mouse
  publication-title: Endocrinology
  doi: 10.1210/endo-113-2-535
– volume: 124
  start-page: 267
  year: 2002
  ident: 10.1016/j.fertnstert.2010.03.034_bib79
  article-title: Promotion of intragranular co-aggregation with LH by enhancement of secretogranin II storage resulted in increased intracellular granule storage in gonadotrophs of GnRH-deprived male mice
  publication-title: Reproduction
  doi: 10.1530/rep.0.1240267
– volume: 96
  start-page: 285
  year: 1991
  ident: 10.1016/j.fertnstert.2010.03.034_bib80
  article-title: Topology of chromogranin A and secretogranin II in the rat anterior pituitary: potential marker proteins for distinct secretory pathways in gonadotrophs
  publication-title: Histochemistry
  doi: 10.1007/BF00271348
– volume: 150
  start-page: 4802
  year: 2009
  ident: 10.1016/j.fertnstert.2010.03.034_bib70
  article-title: Developmental changes in pituitary PACAP expression during the perinatal period: possible role in fetal gonadotroph regulation
  publication-title: Endocrinology
  doi: 10.1210/en.2008-1649
– volume: 61
  start-page: 2112
  year: 2001
  ident: 10.1016/j.fertnstert.2010.03.034_bib237
  article-title: SMAD3 represses androgen receptor–mediated transcription
  publication-title: Cancer Res
– volume: 14
  start-page: 1235
  year: 2000
  ident: 10.1016/j.fertnstert.2010.03.034_bib127
  article-title: Sp1, steroidogenic factor 1 (SF-1), and early growth response protein 1 (EGR-1) binding sites form a tripartite gonadotropin-releasing hormone response element in the rat luteinizing hormone-β gene promoter: an integral role for SF-1
  publication-title: Mol Endocrinol
– volume: 136
  start-page: 67
  year: 1997
  ident: 10.1016/j.fertnstert.2010.03.034_bib252
  article-title: A 361 base pair region of the rat FSH-β promoter contains multiple progesterone receptor–binding sequences and confers progesterone responsiveness
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/S0303-7207(97)00216-5
– volume: 53–54
  start-page: 187
  year: 1983
  ident: 10.1016/j.fertnstert.2010.03.034_bib260
  article-title: Regulation of β-chain mRNA of ovine follicle-stimulating hormone by 17β-estradiol
  publication-title: Mol Cell Biochem
– volume: 196
  start-page: 251
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib77
  article-title: The activin receptor-like kinase 6 Booroola mutation enhances suppressive effects of bone morphogenetic protein 2 (BMP2), BMP4, BMP6 and growth and differentiation factor-9 on FSH release from ovine primary pituitary cell cultures
  publication-title: J Endocrinol
  doi: 10.1677/JOE-07-0148
– volume: 140
  start-page: 1416
  year: 1999
  ident: 10.1016/j.fertnstert.2010.03.034_bib135
  article-title: Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development
  publication-title: Endocrinology
  doi: 10.1210/endo.140.3.6549
– volume: 79
  start-page: 546
  year: 2008
  ident: 10.1016/j.fertnstert.2010.03.034_bib211
  article-title: A proteomic comparison of immature and mature mouse gonadotrophs reveals novel differentially expressed nuclear proteins that regulate gonadotropin gene transcription and RNA splicing
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.108.068106
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Snippet The pituitary gonadotropin hormones, FSH and LH, are key regulators of reproductive physiology. Though the two hormones are produced by the same cell type,...
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SubjectTerms Activins - physiology
Androgens - physiology
Animals
Base Sequence
Biological and medical sciences
Cell Line
Estrogens - physiology
Female
Follicle Stimulating Hormone, beta Subunit - biosynthesis
Follicle Stimulating Hormone, beta Subunit - secretion
Follistatin - physiology
GATA2 Transcription Factor - physiology
Gene Expression Regulation
Glycoprotein Hormones, alpha Subunit
Gonadotrophs - metabolism
Gonadotropin-Releasing Hormone - physiology
Gynecology. Andrology. Obstetrics
Homeodomain Proteins - genetics
Homeodomain Proteins - physiology
Humans
Inhibins - physiology
Internal Medicine
LIM-Homeodomain Proteins
Male
Medical sciences
Molecular Sequence Data
Obstetrics and Gynecology
Paired Box Transcription Factors - physiology
Promoter Regions, Genetic - physiology
Sequence Alignment
Species Specificity
Steroidogenic Factor 1 - physiology
Transcription Factors
Title Mechanisms of FSH synthesis: what we know, what we don't, and why you should care
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https://www.clinicalkey.es/playcontent/1-s2.0-S0015028210004711
https://dx.doi.org/10.1016/j.fertnstert.2010.03.034
https://www.ncbi.nlm.nih.gov/pubmed/20403589
https://www.proquest.com/docview/733182342
Volume 93
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