Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies - Wrapp, Daniel; De Vlieger, Dorien; Corbett, Kizzmekia S.; Torres, Gretel M.; Wang, Nianshuang; Van Breedam, Wander; Roose, Kenny; van Schie, Loes; Hoffmann, Markus; Pöhlmann, Stefan; Graham, Barney S.; Callewaert, Nico; et al. (Cell, 2020)
Keywords: Animals; antibodies; Antibodies, Neutralizing - chemistry; Antibodies, Neutralizing - immunology; Antibodies, Neutralizing - isolation & purification; Betacoronavirus - immunology; Camelidae; Camelids, New World - immunology; Coronavirus infections; Coronavirus Infections - therapy; COVID-19; cross reaction; Cross Reactions; crystal structure; epitopes; humans; immunoglobulin G; Immunoglobulin G - chemistry; Immunoglobulin G - immunology; llamas; membrane fusion; MERS; Middle East respiratory syndrome coronavirus; Models, Molecular; nanobody; neutralization; Pandemics; Pneumonia, Viral - therapy; Protein Domains; receptors; Receptors, Virus - chemistry; SARS; SARS-CoV-2; Single-Domain Antibodies - chemistry; Single-Domain Antibodies - immunology; Single-Domain Antibodies - isolation & purification; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - immunology; therapeutics; viruses; COVID-19; SARS; SARS-CoV-2; nanobody; MERS