Tear Osmolarity in the Diagnosis and Management of Dry Eye Disease

• Published in: American journal of ophthalmology Vol. 151; no. 5; pp. 792 - 798.e1
• Main Authors: Lemp, Michael A., Bron, Anthony J., Baudouin, Christophe, Benítez del Castillo, José M., Geffen, David, Tauber, Joe, Foulks, Gary N., Pepose, Jay S., Sullivan, Benjamin D.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.05.2011; Elsevier; Elsevier Limited
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Clinical medicine; Diagnostic Techniques, Ophthalmological; Disease; Dry Eye Syndromes - classification; Dry Eye Syndromes - diagnosis; Dry Eye Syndromes - therapy; Eye diseases; Female; Fluorophotometry; Health Insurance Portability & Accountability Act 1996-US; Humans; Lacrimal Apparatus - chemistry; Male; Medical sciences; Medical treatment; Meibomian Glands - chemistry; Middle Aged; Miscellaneous; Ophthalmology; Osmolar Concentration; Pathogenesis; Prospective Studies; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Staining and Labeling; Tears - chemistry; Young Adult; Dry eye syndrome; Eye disease; Clinical management; Osmolarity; Tear; Dry eye; Diagnosis; Ophthalmology

To evaluate the use of tear osmolarity in the diagnosis of dry eye disease. A prospective, observational case series to determine the clinical usefulness of tear osmolarity and commonly used objective tests to diagnose dry eye disease. A multicenter, 10-site study consisting of 314 consecutive subje...