Gut microbiota-mediated pharmacokinetics of ginseng saponins

• Published in: Journal of ginseng research Vol. 42; no. 3; pp. 255 - 263
• Main Author: Kim, Dong-Hyun
• Format: Journal Article
• Language: English
• Published: Korea (South) Elsevier B.V 01.07.2018; 고려인삼학회; Elsevier
• Subjects: fermentation; ginseng; ginsenoside; gut microbiota; metabolism; Review; 기타의약학; ginsenoside; fermentation; metabolism; ginseng; gut microbiota

Orally administered ginsengs come in contact with the gut microbiota, and their hydrophilic constituents, such as ginsenosides, are metabolized to hydrophobic compounds by gastric juice and gut microbiota: protopanxadiol-type ginsenosides are mainly transformed into compound K and ginsenoside Rh2; p...