Factors associated with the platelet count in patients with chronic hepatitis C

• Published in: Thrombosis research Vol. 135; no. 5; pp. 823 - 828
• Main Authors: Tana, Michele M., Zhao, Xiongce, Bradshaw, Alyson, Moon, Mi Sun, Page, Sandy, Turner, Tiffany, Rivera, Elenita, Kleiner, David E., Heller, Theo
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.05.2015
• Subjects: Adult; Biopsy; Blood Platelets - metabolism; Conceptual model; Cross-Sectional Studies; Female; Fibrosis - blood; Hematology, Oncology and Palliative Medicine; Hepatitis C, Chronic - blood; Humans; Immunoglobulin G - blood; Liver - pathology; Liver Cirrhosis - blood; Male; Middle Aged; Non-invasive markers; Organ Size; P-Selectin - metabolism; Platelet biology; Platelet Count; Platelet Glycoprotein GPIb-IX Complex - metabolism; Retrospective Studies; Spleen - pathology; Thrombopoietin - blood; von Willebrand Factor - metabolism; TE; TPO; Platelet biology; vWF; IgG; Non-invasive markers; HCV; Conceptual model; IPF; CHC; thrombopoietin; immunoglobulin G; immature platelet fraction; chronic hepatitis C; transient elastography; hepatitis C virus; von Willebrand Factor

There are many potential causes of thrombocytopenia in patients with chronic hepatitis C (CHC). We sought to determine the association between thrombopoietin (TPO) level, immature platelet fraction (IPF), immunoglobulin G (IgG) level, spleen size, and the platelet count in CHC. We studied a consecut...