DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins - Patel, Anamika; Yang, Peng; Tinkham, Matthew; Pradhan, Mihika; Sun, Ming-An; Wang, Yixuan; Hoang, Don; Wolf, Gernot; Horton, John R.; Zhang, Xing; Macfarlan, Todd; Cheng, Xiaodong (Cell, 2018)
Keywords: Amino Acid Sequence; Animals; AT-rich; Base Sequence; BASIC BIOLOGICAL SCIENCES; binding capacity; Binding Sites; C2H2 zinc fingers; Carrier Proteins - chemistry; Carrier Proteins - classification; Carrier Proteins - genetics; Carrier Proteins - metabolism; DNA; DNA - chemistry; DNA - metabolism; DNA conformation; evolution; Humans; Igf2; imprinting; insulin-like growth factor II; Insulin-Like Growth Factor II - chemistry; Insulin-Like Growth Factor II - genetics; Insulin-Like Growth Factor II - metabolism; KRAB; Mice; Molecular Dynamics Simulation; mutation; Nuclear Proteins - chemistry; Nuclear Proteins - classification; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Nucleic Acid Conformation; Pan troglodytes; Phylogeny; Polymorphism, Single Nucleotide; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins - biosynthesis; Recombinant Proteins - chemistry; Recombinant Proteins - isolation & purification; Sequence Alignment; shortened minor groove; thymine; transcription factors; Zfp568; zinc finger motif; imprinting; Zfp568; C2H2 zinc fingers; DNA conformation; Igf2; shortened minor groove; KRAB; AT-rich