Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene - Wei, Ya Bin; Melas, Philippe A.; Wegener, Gregers; Mathé, Aleksander A.; Lavebratt, Catharina (The international journal of neuropsychopharmacology, 2015)
Keywords: Animals; Antidepressants; Antidepressive Agents - pharmacology; Brain-derived neurotrophic factor; Brain-Derived Neurotrophic Factor - genetics; Brain-Derived Neurotrophic Factor - metabolism; Butyric Acid - pharmacology; Depressive Disorder - drug therapy; Depressive Disorder - genetics; Depressive Disorder - metabolism; Dioxygenases - metabolism; Disease Models, Animal; DNA methylation; DNA Methylation - drug effects; Epigenetics; Histone Deacetylase Inhibitors - pharmacology; Male; Prefrontal Cortex - drug effects; Prefrontal Cortex - metabolism; Rats; Up-Regulation - drug effects; DNA methylation; TET1; depression; epigenetics