Dietary alpha‐ketoglutarate promotes beige adipogenesis and prevents obesity in middle‐aged mice - Tian, Qiyu; Zhao, Junxing; Yang, Qiyuan; Wang, Bo; Deavila, Jeanene M.; Zhu, Mei-Jun; Du, Min (Aging cell, 2020)
Keywords: Adipocytes; Adipogenesis; Adipogenesis - drug effects; Adipose tissue (brown); adipose tissue browning; Adipose tissues; Aging; alpha‐ketoglutarate; Animals; Body fat; Body weight; Body weight gain; Demethylation; Deoxyribonucleic acid; Dextrose; Diabetes mellitus; Dietary supplements; DNA; DNA demethylation; DNA methylation; Fatty acids; Female; Genes; Glucose; Glucose tolerance; High fat diet; Hypertrophy; Ketoglutaric acid; Ketoglutaric Acids - pharmacology; Ketoglutaric Acids - therapeutic use; Metabolic disorders; Metabolism; Methylation; Mice; Obesity; Obesity - drug therapy; Obesity - prevention & control; Original; Proteins; DNA demethylation; aging; glucose tolerance; alpha-ketoglutarate; adipose tissue browning; high-fat diet