Novel alleles of rice eIF4G generated by CRISPR/Cas9‐targeted mutagenesis confer resistance to Rice tungro spherical virus

• Published in: Plant biotechnology journal Vol. 16; no. 11; pp. 1918 - 1927
• Main Authors: Macovei, Anca, Sevilla, Neah R., Cantos, Christian, Jonson, Gilda B., Slamet‐Loedin, Inez, Čermák, Tomáš, Voytas, Daniel F., Choi, Il‐Ryong, Chadha‐Mohanty, Prabhjit
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.11.2018; John Wiley and Sons Inc
• Subjects: Alleles; Allelomorphism; Asia; biotechnology; CRISPR; CRISPR-Cas systems; CRISPR/Cas9; Crop production; Cultivars; Disease resistance; eIF4G; greenhouses; homozygosity; Initiation factor eIF-4G; mutagenesis; Mutation; Mutation rates; Oryza; Residues; Rice; Rice tungro bacilliform virus; Rice tungro spherical virus; Site-directed mutagenesis; Tungro; Viruses; Asia; rice tungro spherical virus; CRISPR/Cas9; eIF4G; rice; mutagenesis

Summary Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incid...