Novel alleles of rice eIF4G generated by CRISPR/Cas9‐targeted mutagenesis confer resistance to Rice tungro spherical virus
Summary Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incid...
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| Published in | Plant biotechnology journal Vol. 16; no. 11; pp. 1918 - 1927 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
John Wiley & Sons, Inc
01.11.2018
John Wiley and Sons Inc |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Summary
Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y1059V1060V1061 residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV‐susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in‐frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV‐resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV‐resistant varieties. |
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| AbstractList | Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between
Rice tungro spherical virus
(RTSV) and
Rice tungro bacilliform virus
. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y
1059
V
1060
V
1061
residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in
eIF4G
were generated using the CRISPR/Cas9 system in the RTSV‐susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated
eIF4G
alleles examined, only those resulting in in‐frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that
eIF4G
is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV‐resistant plants with the novel
eIF4G
alleles represent a valuable material to develop more diverse RTSV‐resistant varieties. Summary Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y1059V1060V1061 residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV‐susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in‐frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV‐resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV‐resistant varieties. Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y1059 V1060 V1061 residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV-susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in-frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV-resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV-resistant varieties.Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y1059 V1060 V1061 residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV-susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in-frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV-resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV-resistant varieties. Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y[sup.1059]V[sup.1060]V[sup.1061] residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV-susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in-frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV-resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV-resistant varieties. Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y¹⁰⁵⁹V¹⁰⁶⁰V¹⁰⁶¹ residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV‐susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in‐frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV‐resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV‐resistant varieties. Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y V V residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV-susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in-frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV-resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV-resistant varieties. Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y1059V1060V1061 residues of eIF4G are known to be associated with the reactions to RTSV. To develop new sources of resistance to RTD, mutations in eIF4G were generated using the CRISPR/Cas9 system in the RTSV‐susceptible variety IR64, widely grown across tropical Asia. The mutation rates ranged from 36.0% to 86.6%, depending on the target site, and the mutations were successfully transmitted to the next generations. Among various mutated eIF4G alleles examined, only those resulting in in‐frame mutations in SVLFPNLAGKS residues (mainly NL), adjacent to the YVV residues, conferred resistance. Furthermore, our data suggest that eIF4G is essential for normal development, as alleles resulting in truncated eIF4G could not be maintained in homozygous state. The final products with RTSV resistance and enhanced yield under glasshouse conditions were found to no longer contain the Cas9 sequence. Hence, the RTSV‐resistant plants with the novel eIF4G alleles represent a valuable material to develop more diverse RTSV‐resistant varieties. |
| Audience | Academic |
| Author | Macovei, Anca Slamet‐Loedin, Inez Cantos, Christian Voytas, Daniel F. Čermák, Tomáš Chadha‐Mohanty, Prabhjit Sevilla, Neah R. Jonson, Gilda B. Choi, Il‐Ryong |
| AuthorAffiliation | 1 Genetics and Biotechnology Division International Rice Research Institute (IRRI) Metro Manila Philippines 2 Department of Genetics Cell Biology & Development and Center for Genome Engineering University of Minnesota Minneapolis MN USA 4 Present address: Huck Institute of the Life Sciences Pennsylvania State University University Park PA USA 3 Present address: Department of Biology and Biotechnology ‘L. Spallanzani’ University of Pavia Pavia Italy |
| AuthorAffiliation_xml | – name: 4 Present address: Huck Institute of the Life Sciences Pennsylvania State University University Park PA USA – name: 1 Genetics and Biotechnology Division International Rice Research Institute (IRRI) Metro Manila Philippines – name: 3 Present address: Department of Biology and Biotechnology ‘L. Spallanzani’ University of Pavia Pavia Italy – name: 2 Department of Genetics Cell Biology & Development and Center for Genome Engineering University of Minnesota Minneapolis MN USA |
| Author_xml | – sequence: 1 givenname: Anca surname: Macovei fullname: Macovei, Anca organization: International Rice Research Institute (IRRI) – sequence: 2 givenname: Neah R. surname: Sevilla fullname: Sevilla, Neah R. organization: International Rice Research Institute (IRRI) – sequence: 3 givenname: Christian surname: Cantos fullname: Cantos, Christian organization: International Rice Research Institute (IRRI) – sequence: 4 givenname: Gilda B. surname: Jonson fullname: Jonson, Gilda B. organization: International Rice Research Institute (IRRI) – sequence: 5 givenname: Inez surname: Slamet‐Loedin fullname: Slamet‐Loedin, Inez organization: International Rice Research Institute (IRRI) – sequence: 6 givenname: Tomáš surname: Čermák fullname: Čermák, Tomáš organization: University of Minnesota – sequence: 7 givenname: Daniel F. surname: Voytas fullname: Voytas, Daniel F. organization: University of Minnesota – sequence: 8 givenname: Il‐Ryong surname: Choi fullname: Choi, Il‐Ryong organization: International Rice Research Institute (IRRI) – sequence: 9 givenname: Prabhjit orcidid: 0000-0002-7044-1851 surname: Chadha‐Mohanty fullname: Chadha‐Mohanty, Prabhjit email: pchadhamohanty@gmail.com organization: International Rice Research Institute (IRRI) |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29604159$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1007/s12571-012-0168-1 10.1038/srep11491 10.1105/tpc.16.00922 10.1111/j.1365-313X.2006.02792.x 10.1094/Phyto-86-25 10.1111/pbi.12465 10.1016/j.pbi.2016.11.011 10.1016/S0968-0004(00)01628-5 10.1094/PDIS-91-11-1386 10.1111/pbi.12448 10.1094/PD-72-0843 10.1128/MCB.15.9.4990 10.1038/hortres.2015.19 10.1371/journal.pbio.1001878 10.1094/PD-74-0923 10.1093/mp/ssu044 10.1007/978-1-62703-715-0_21 10.3389/fpls.2016.00765 10.1038/ng.3484 10.1093/nar/gkw1135 10.1186/1746-4811-9-39 10.1038/srep19675 10.1016/j.cell.2009.01.042 10.1038/srep21451 10.2135/cropsci2007.03.0127 10.1111/mpp.12417 10.1023/A:1012605218343 10.1093/nar/16.20.9877 10.1094/MPMI-22-10-1268 10.1038/nmeth.2812 10.1186/s12284-015-0069-y 10.1038/nbt.2650 10.1094/Phyto-77-473 10.1146/annurev.phyto.34.1.275 10.1111/mpp.12375 10.3390/v7072778 10.1371/journal.pbio.1001877 10.1038/cr.2013.123 10.1016/S0065-3527(06)66001-6 10.1094/PDIS.2002.86.2.88 10.1094/Phyto-85-77 10.1094/MPMI-23-1-0029 10.1038/srep24765 10.1094/MPMI-03-10-0073 10.1111/pbi.12200 10.3389/fpls.2016.01673 10.1016/j.virusres.2005.10.010 10.1016/j.molp.2016.12.001 10.1073/pnas.1400822111 10.1016/j.tplants.2016.08.009 10.1016/j.virol.2005.09.031 |
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| References | 1987; 77 2017; 4 2013; 23 1988; 72 1996; 34 2010; 23 2013; 11 2002; 86 2000 2017; 36 2006; 66 2004; 36 2014; 7 2016; 48 2003; 85 2014; 12 2014; 11 2001; 122 2015; 2 2009; 22 1990; 74 2006; 119 2015; 19 2016; 19 2000; 25 1995; 15 2017; 22 1988; 16 2007; 91 1994 2017; 29 2016; 17 2014; 111 2015; 8 2015; 7 2016; 14 2009; 136 1999 1980; 17 1995; 85 1993; 14 2016; 6 2016; 7 1994; 19 2017; 10 2006; 47 2013; 31 2008; 48 2014; 1099 2016; 27 2012; 4 1996; 86 2006; 344 e_1_2_8_28_1 e_1_2_8_24_1 e_1_2_8_47_1 e_1_2_8_49_1 Rao G.M. (e_1_2_8_43_1) 1980; 17 e_1_2_8_7_1 e_1_2_8_9_1 e_1_2_8_20_1 Muralidharan K. (e_1_2_8_38_1) 2003; 85 e_1_2_8_22_1 e_1_2_8_45_1 e_1_2_8_41_1 e_1_2_8_60_1 e_1_2_8_17_1 e_1_2_8_19_1 e_1_2_8_13_1 e_1_2_8_36_1 e_1_2_8_59_1 Cabunagan R.C. (e_1_2_8_10_1) 1999 e_1_2_8_57_1 e_1_2_8_32_1 e_1_2_8_55_1 Stewart C.N. (e_1_2_8_52_1) 1993; 14 e_1_2_8_11_1 e_1_2_8_34_1 e_1_2_8_53_1 e_1_2_8_51_1 e_1_2_8_30_1 e_1_2_8_29_1 e_1_2_8_25_1 e_1_2_8_46_1 e_1_2_8_27_1 e_1_2_8_48_1 Anjaneyulu A. (e_1_2_8_3_1) 1994 Ebron L.A. (e_1_2_8_15_1) 1994; 19 e_1_2_8_2_1 e_1_2_8_4_1 e_1_2_8_6_1 e_1_2_8_8_1 e_1_2_8_21_1 e_1_2_8_42_1 e_1_2_8_23_1 e_1_2_8_44_1 e_1_2_8_40_1 e_1_2_8_18_1 e_1_2_8_39_1 e_1_2_8_14_1 e_1_2_8_35_1 e_1_2_8_16_1 e_1_2_8_37_1 e_1_2_8_58_1 Azzam O. (e_1_2_8_5_1) 2000 Khush G.S. (e_1_2_8_26_1) 2004; 36 e_1_2_8_31_1 e_1_2_8_56_1 e_1_2_8_12_1 e_1_2_8_33_1 e_1_2_8_54_1 e_1_2_8_50_1 |
| References_xml | – volume: 122 start-page: 91 year: 2001 end-page: 97 article-title: Inheritance of resistance to rice tungro spherical virus in a near‐isogenic line derived from Utri Merah and in rice cultivar TKM6 publication-title: Euphytica – volume: 25 start-page: 423 year: 2000 end-page: 426 article-title: Novel eIF4G domain homologues linking mRNA translation with nonsense‐mediated mRNA decay publication-title: Trends Biochem. Sci. – volume: 17 start-page: 1140 year: 2016 end-page: 1153 article-title: Development of broad virus resistance in non‐transgenic cucumber using CRISPR/Cas9 technology publication-title: Mol. Plant Pathol. – start-page: 40 year: 2000 – volume: 34 start-page: 275 year: 1996 end-page: 297 article-title: Molecular biology of rice tungro viruses publication-title: Annu. Rev. Phytopathol. – volume: 6 start-page: 24765 year: 2016 article-title: CRISPR/Cas9‐mediated efficient and heritable targeted mutagenesis in tomato plants in the first and later generations publication-title: Sci. Rep. – volume: 36 start-page: 1 year: 2017 end-page: 8 article-title: Applying CRISPR/Cas for genome engineering in plants: the best is yet to come publication-title: Curr. Opin. Plant Biol. – volume: 7 start-page: 765 year: 2016 article-title: An overview of CRISPR‐based tools and their implementations: new opportunities in understanding plant‐pathogen interactions for better crop production publication-title: Front. Plant Sci. – volume: 17 start-page: 1276 year: 2016 end-page: 1288 article-title: Engineering of CRISPR/Cas9‐ mediated potyvirus resistance in transgene‐free plants publication-title: Mol. Plant Pathol. – volume: 7 start-page: 1494 year: 2014 end-page: 1496 article-title: CRISPR‐P: a web tool for synthetic single‐guide RNA design of CRISPR‐system in plants publication-title: Mol. Plant – volume: 77 start-page: 473 year: 1987 end-page: 476 article-title: Infectivity neutralization of rice tungro associated viruses acquired by vector leafhoppers publication-title: Phytopathology – volume: 14 start-page: 448 year: 2016 end-page: 462 article-title: Designed nucleases for targeted genome editing publication-title: Plant Biotechnol. J. – volume: 47 start-page: 417 year: 2006 end-page: 426 article-title: Mutations in the eIF(iso)4G translation initiation factor confer high resistance to rice yellow mottle virus publication-title: Plant J. – volume: 8 start-page: 34 year: 2015 article-title: Allele mining and enhanced genetic recombination for rice breeding publication-title: Rice – volume: 11 start-page: 39 year: 2013 article-title: Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system publication-title: Plant Methods – volume: 22 start-page: 1268 year: 2009 end-page: 1281 article-title: Suppression of two tungro viruses in rice by separable traits originating from cultivar Utri Merah publication-title: Mol. Plant‐Microbe – volume: 16 start-page: 9877 year: 1988 article-title: Storage of competent cells for transformation publication-title: Nucleic Acids Res. – volume: 48 start-page: 480 year: 2008 end-page: 486 article-title: Characterization of a putative rice mutant for reaction to rice tungro disease publication-title: Crop Sci. – year: 1994 – volume: 72 start-page: 843 year: 1988 end-page: 847 article-title: Resistance to rice tungro spherical virus in rice publication-title: Plant Dis. – volume: 48 start-page: 109 year: 2016 end-page: 111 article-title: A proposed regulatory framework for genome‐edited crops publication-title: Nat. Genet. – volume: 86 start-page: 25 year: 1996 end-page: 30 article-title: Molecular mapping of resistance to rice tungro spherical virus and green leafhopper publication-title: Phytopathology – volume: 31 start-page: 686 year: 2013 end-page: 688 article-title: Targeted genome modification of crop plants using a CRISPR‐Cas system publication-title: Nat. Biotechnol. – volume: 344 start-page: 185 year: 2006 end-page: 197 article-title: Translational control in positive strand RNA viruses publication-title: Virology – volume: 27 start-page: 19675 year: 2016 article-title: Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system publication-title: Sci. Rep. – volume: 14 start-page: 483 year: 2016 end-page: 495 article-title: Use of designer nucleases for targeted gene and genome editing in plants publication-title: Plant Biotechnol. J. – start-page: 45 year: 1999 end-page: 55 – volume: 136 start-page: 731 year: 2009 end-page: 745 article-title: Regulation of translation initiation in eukaryotes: mechanisms and biological targets publication-title: Cell – volume: 11 start-page: 122 year: 2014 end-page: 123 article-title: E‐CRISP: fast CRISPR target site identification publication-title: Nat. Methods – volume: 23 start-page: 1233 year: 2013 end-page: 1236 article-title: Targeted mutagenesis in rice using CRISPR‐Cas system publication-title: Cell Res. – volume: 12 start-page: e1001878 year: 2014 article-title: Lab to farm: applying research on plant genetics and genomics to crop improvement publication-title: PLoS Biol. – volume: 4 start-page: 7 year: 2012 end-page: 24 article-title: Crops that feed the world 7: rice publication-title: Food Sec. – volume: 23 start-page: 1506 year: 2010 end-page: 1513 article-title: Direct interaction between the Rice yellow mottle virus (RYMV) VPg and the central domain of the rice eIF(iso)4G1 factor correlates with rice susceptibility and RYMV virulence publication-title: Mol. Plant‐Microbe Interact. – volume: 85 start-page: 77 year: 1995 end-page: 81 article-title: Biological variants of rice tungro viruses in the Philippines publication-title: Phytopathology – volume: 10 start-page: 526 year: 2017 end-page: 529 article-title: Generation of targeted point mutations in rice by a modified CRISPR/Cas9 system publication-title: Mol. Plant – volume: 2 start-page: 15019 year: 2015 article-title: Genome‐editing technologies and their potential application in horticultural crop breeding publication-title: Hortic. Res. – volume: 17 start-page: 210 year: 1980 end-page: 214 article-title: Estimation of yield losses due to tungro virus infection in rice cultivars publication-title: Oryza – volume: 15 start-page: 4990 year: 1995 end-page: 4997 article-title: The translation initiation factor eIF‐4E binds to a common motif shared by the translation factor eIF‐4 gamma and the translational repressors 4E‐binding proteins publication-title: Mol. Cell. Biol. – volume: 1099 start-page: 261 year: 2014 end-page: 271 article-title: mediated transformation: rice transformation publication-title: Methods Mol. Biol. – volume: 36 start-page: 101 year: 2004 end-page: 106 article-title: Breeding rice for resistance to tungro virus at IRRI publication-title: SABRAO J. Breed. Genet. – volume: 29 start-page: 1196 year: 2017 end-page: 1217 article-title: A multipurpose toolkit to enable advanced genome engineering in plants publication-title: Plant Cell – volume: 19 start-page: 10 year: 1994 end-page: 11 article-title: Inheritance of resistance to rice tungro spherical virus in some rice cultivars publication-title: Int. Rice Res. Notes – volume: 119 start-page: 63 year: 2006 end-page: 75 article-title: Cap‐independent translation of plant viral RNAs publication-title: Virus Res. – volume: 12 start-page: 797 year: 2014 end-page: 807 article-title: The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation publication-title: Plant Biotechnol. J. – volume: 7 start-page: 3392 year: 2015 end-page: 3419 article-title: Plant translation factors and virus resistance publication-title: Viruses – volume: 91 start-page: 1386 year: 2007 end-page: 1391 article-title: Characterization of ‐derived resistance to tungro disease in rice publication-title: Plant Dis. – volume: 86 start-page: 88 year: 2002 end-page: 100 article-title: The biology, epidemiology, and management of rice tungro disease in Asia publication-title: Plant Dis. – volume: 111 start-page: 4632 year: 2014 end-page: 4637 article-title: Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas‐induced gene modifications in publication-title: Proc. Natl Acad. Sci. USA – volume: 66 start-page: 1 year: 2006 end-page: 29 article-title: Spread of plant virus disease to new plantings: a case study of rice tungro disease publication-title: Adv. Virus Res. – volume: 19 start-page: 11491 year: 2015 article-title: Generation of inheritable and “transgene clean” targeted genome‐modified rice in later generations using the CRISPR/Cas9 system publication-title: Sci. Rep. – volume: 4 start-page: D1075 year: 2017 end-page: D1081 article-title: Rice SNP‐seek database update: new SNPs, indels, and queries publication-title: Nucleic Acids Res. – volume: 22 start-page: 38 year: 2017 end-page: 52 article-title: Characteristics of genome editing mutations in cereal crops publication-title: Trends Plant Sci. – volume: 19 start-page: 21451 year: 2016 article-title: Selection of highly efficient sgRNAs for CRISPR/Cas9‐based plant genome editing publication-title: Sci. Rep. – volume: 12 start-page: e1001877 year: 2014 article-title: Precision genome engineering and agriculture: opportunities and regulatory challenges publication-title: PLoS Biol. – volume: 23 start-page: 29 year: 2010 end-page: 38 article-title: Single nucleotide polymorphisms in a gene for translation initiation factor (eIF4G) of rice ( ) associated with resistance to rice tungro spherical virus publication-title: Mol. Plant‐Microbe Interact. – volume: 74 start-page: 923 year: 1990 end-page: 926 article-title: Resistances in rice to tungro‐associated viruses publication-title: Plant Dis. – volume: 85 start-page: 1143 year: 2003 end-page: 1147 article-title: Tungro epidemic and yield losses in paddy fields in India publication-title: Curr. Sci. – volume: 14 start-page: 748 year: 1993 end-page: 750 article-title: A rapid CTAB DNA isolation technique useful for RAPD fingerprinting and other PCR applications publication-title: Biotechniques – volume: 7 start-page: 1673 year: 2016 article-title: Engineering plant immunity: using CRISPR/Cas9 to generate virus resistance publication-title: Front. Plant Sci. – ident: e_1_2_8_47_1 doi: 10.1007/s12571-012-0168-1 – ident: e_1_2_8_56_1 doi: 10.1038/srep11491 – ident: e_1_2_8_11_1 doi: 10.1105/tpc.16.00922 – ident: e_1_2_8_2_1 doi: 10.1111/j.1365-313X.2006.02792.x – ident: e_1_2_8_46_1 doi: 10.1094/Phyto-86-25 – ident: e_1_2_8_29_1 doi: 10.1111/pbi.12465 – ident: e_1_2_8_41_1 doi: 10.1016/j.pbi.2016.11.011 – volume: 14 start-page: 748 year: 1993 ident: e_1_2_8_52_1 article-title: A rapid CTAB DNA isolation technique useful for RAPD fingerprinting and other PCR applications publication-title: Biotechniques – ident: e_1_2_8_40_1 doi: 10.1016/S0968-0004(00)01628-5 – ident: e_1_2_8_49_1 doi: 10.1094/PDIS-91-11-1386 – ident: e_1_2_8_54_1 doi: 10.1111/pbi.12448 – ident: e_1_2_8_21_1 doi: 10.1094/PD-72-0843 – ident: e_1_2_8_35_1 doi: 10.1128/MCB.15.9.4990 – ident: e_1_2_8_55_1 doi: 10.1038/hortres.2015.19 – ident: e_1_2_8_44_1 doi: 10.1371/journal.pbio.1001878 – ident: e_1_2_8_22_1 doi: 10.1094/PD-74-0923 – ident: e_1_2_8_30_1 doi: 10.1093/mp/ssu044 – volume: 19 start-page: 10 year: 1994 ident: e_1_2_8_15_1 article-title: Inheritance of resistance to rice tungro spherical virus in some rice cultivars publication-title: Int. Rice Res. Notes – ident: e_1_2_8_50_1 doi: 10.1007/978-1-62703-715-0_21 – ident: e_1_2_8_7_1 doi: 10.3389/fpls.2016.00765 – ident: e_1_2_8_24_1 doi: 10.1038/ng.3484 – ident: e_1_2_8_36_1 doi: 10.1093/nar/gkw1135 – ident: e_1_2_8_8_1 doi: 10.1186/1746-4811-9-39 – ident: e_1_2_8_34_1 doi: 10.1038/srep19675 – ident: e_1_2_8_51_1 doi: 10.1016/j.cell.2009.01.042 – ident: e_1_2_8_33_1 doi: 10.1038/srep21451 – ident: e_1_2_8_58_1 doi: 10.2135/cropsci2007.03.0127 – volume-title: Rice Tungro year: 1994 ident: e_1_2_8_3_1 – ident: e_1_2_8_42_1 doi: 10.1111/mpp.12417 – ident: e_1_2_8_6_1 doi: 10.1023/A:1012605218343 – start-page: 40 volume-title: Methods for Evaluating Resistance to Rice Tungro Disease year: 2000 ident: e_1_2_8_5_1 – ident: e_1_2_8_23_1 doi: 10.1093/nar/16.20.9877 – ident: e_1_2_8_16_1 doi: 10.1094/MPMI-22-10-1268 – ident: e_1_2_8_19_1 doi: 10.1038/nmeth.2812 – ident: e_1_2_8_31_1 doi: 10.1186/s12284-015-0069-y – ident: e_1_2_8_48_1 doi: 10.1038/nbt.2650 – ident: e_1_2_8_20_1 doi: 10.1094/Phyto-77-473 – ident: e_1_2_8_25_1 doi: 10.1146/annurev.phyto.34.1.275 – ident: e_1_2_8_13_1 doi: 10.1111/mpp.12375 – ident: e_1_2_8_45_1 doi: 10.3390/v7072778 – ident: e_1_2_8_53_1 doi: 10.1371/journal.pbio.1001877 – ident: e_1_2_8_37_1 doi: 10.1038/cr.2013.123 – volume: 85 start-page: 1143 year: 2003 ident: e_1_2_8_38_1 article-title: Tungro epidemic and yield losses in paddy fields in India publication-title: Curr. Sci. – ident: e_1_2_8_12_1 doi: 10.1016/S0065-3527(06)66001-6 – ident: e_1_2_8_4_1 doi: 10.1094/PDIS.2002.86.2.88 – volume: 36 start-page: 101 year: 2004 ident: e_1_2_8_26_1 article-title: Breeding rice for resistance to tungro virus at IRRI publication-title: SABRAO J. Breed. Genet. – ident: e_1_2_8_9_1 doi: 10.1094/Phyto-85-77 – start-page: 45 volume-title: Rice Tungro Disease Management year: 1999 ident: e_1_2_8_10_1 – ident: e_1_2_8_28_1 doi: 10.1094/MPMI-23-1-0029 – ident: e_1_2_8_39_1 doi: 10.1038/srep24765 – ident: e_1_2_8_18_1 doi: 10.1094/MPMI-03-10-0073 – ident: e_1_2_8_59_1 doi: 10.1111/pbi.12200 – ident: e_1_2_8_57_1 doi: 10.3389/fpls.2016.01673 – ident: e_1_2_8_27_1 doi: 10.1016/j.virusres.2005.10.010 – ident: e_1_2_8_32_1 doi: 10.1016/j.molp.2016.12.001 – volume: 17 start-page: 210 year: 1980 ident: e_1_2_8_43_1 article-title: Estimation of yield losses due to tungro virus infection in rice cultivars publication-title: Oryza – ident: e_1_2_8_17_1 doi: 10.1073/pnas.1400822111 – ident: e_1_2_8_60_1 doi: 10.1016/j.tplants.2016.08.009 – ident: e_1_2_8_14_1 doi: 10.1016/j.virol.2005.09.031 |
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Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro... Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus... Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus... |
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| SubjectTerms | Alleles Allelomorphism Asia biotechnology CRISPR CRISPR-Cas systems CRISPR/Cas9 Crop production Cultivars Disease resistance eIF4G greenhouses homozygosity Initiation factor eIF-4G mutagenesis Mutation Mutation rates Oryza Residues Rice Rice tungro bacilliform virus Rice tungro spherical virus Site-directed mutagenesis Tungro Viruses |
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| Title | Novel alleles of rice eIF4G generated by CRISPR/Cas9‐targeted mutagenesis confer resistance to Rice tungro spherical virus |
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