Pick the best of both glucose and lipid metabolism

Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinic...

Full description

Saved in:
Bibliographic Details
Published inJournal of diabetes investigation Vol. 13; no. 7; pp. 1132 - 1133
Main Authors Shimizu, Tatsunori, Takahashi, Yuya, Fujita, Hiroki, Waki, Hironori
Format Journal Article
LanguageEnglish
Published Japan John Wiley & Sons, Inc 01.07.2022
John Wiley and Sons Inc
Wiley
Subjects
Adipocytes
Body fat
Commentaries
Diabetes
Glucose
Glucose metabolism
Insulin
Insulin resistance
Insulin-like growth factors
Kinases
Lipid metabolism
Lipogenesis
Liver diseases
Musculoskeletal system
Phosphorylation
Protein biosynthesis
Protein synthesis
Proteins
Sterols
Online AccessGet full text

Cover

More Information
Summary:Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinical benefits in the treatment of diabetes.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2040-1116
2040-1124
DOI:10.1111/jdi.13774