In vivo effects of focused shock waves on tumor tissue visualized by fluorescence staining techniques

• Published in: Bioelectrochemistry (Amsterdam, Netherlands) Vol. 103; pp. 103 - 110
• Main Authors: Lukes, Petr, Zeman, Jan, Horak, Vratislav, Hoffer, Petr, Pouckova, Pavla, Holubova, Monika, Hosseini, S. Hamid R., Akiyama, Hidenori, Sunka, Pavel, Benes, Jiri
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2015
• Subjects: Animals; Apoptosis; Caspase 3 - metabolism; Electric Stimulation Therapy - instrumentation; Electric Stimulation Therapy - methods; Electrical discharge; Eosine Yellowish-(YS); Equipment Design; Fluorescence; Hematoxylin; Immunohistochemistry - methods; In Situ Nick-End Labeling; Male; Necrosis; Neoplasms, Experimental - pathology; Neoplasms, Experimental - therapy; Rats, Inbred Lew; Shock waves; Tumor damage; Shock waves; Electrical discharge; Tumor damage; Necrosis; Apoptosis

Shock waves can cause significant cytotoxic effects in tumor cells and tissues both in vitro and in vivo. However, understanding the mechanisms of shock wave interaction with tissues is limited. We have studied in vivo effects of focused shock waves induced in the syngeneic sarcoma tumor model using...