Efficacy of salvage surgery versus re-irradiation for isolated regional lymph node recurrence in patients with nasopharyngeal carcinoma

• Published in: BMC cancer Vol. 24; no. 1; pp. 483 - 10
• Main Authors: Chen, Yuebing, Huang, Yiping, Chen, Xiaoqiang, Chen, Zhiwei, Peng, Xiane, Lin, Shaojun, Lin, Cheng, Zong, Jingfeng
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 16.04.2024; BioMed Central; BMC
• Subjects: Cancer; Cancer therapies; Care and treatment; Chemotherapy; Classification; Diagnosis; Dissection; Epstein-Barr virus; Humans; Lymph node dissection; Lymph nodes; Lymph Nodes - pathology; Lymphatic metastasis; Lymphatic system; Magnetic resonance imaging; Medical prognosis; Metastases; Metastasis; Multivariate analysis; Nasopharyngeal cancer; Nasopharyngeal carcinoma; Nasopharyngeal Carcinoma - pathology; Nasopharyngeal Carcinoma - radiotherapy; Nasopharyngeal Neoplasms - radiotherapy; Nasopharyngeal Neoplasms - surgery; Neck; Neoplasm Recurrence, Local - pathology; Neoplasm Staging; Patient outcomes; Patients; Prognosis; Radiation therapy; Radiotherapy; Re-Irradiation; Recurrence; Regional lymph nodes; Retrospective Studies; Software; Surgery; Survival; Throat cancer; Tomography; Southeast Asia; Nasopharyngeal carcinoma; Recurrence; Re-irradiation; Lymph node dissection; Regional lymph nodes
• ISSN: 1471-2407; 1471-2407
• DOI: 10.1186/s12885-024-12259-w

To compare the clinical characteristics and prognoses of patients with isolated regional lymph node recurrent nasopharyngeal carcinoma (irrNPC) who underwent surgery or re-irradiation treatment. We retrospectively reviewed 124 irrNPC patients who underwent initial radiotherapy between January 2010 a...