Prognostic significance of adjuvant therapy and specific radiation dosages in Taiwanese patients with oral cavity cancer and extra-nodal extension: a nationwide cohort study

• Published in: BMC cancer Vol. 24; no. 1; pp. 1320 - 12
• Main Authors: Tsai, Yao-Te, Chen, Wen-Cheng, Wen, Yu-Wen, Lin, Chien-Yu, Fan, Kang-Hsing, Lin, Jin-Ching, Ng, Shu-Hang, Lee, Shu-Ru, Kang, Chung-Jan, Lee, Li-Yu, Chien, Chih-Yen, Hua, Chun-Hung, Wang, Cheng Ping, Chen, Tsung-Ming, Terng, Shyuang-Der, Tsai, Chi-Ying, Wang, Hung-Ming, Hsieh, Chia-Hsun, Yeh, Chih-Hua, Lin, Chih-Hung, Tsao, Chung-Kan, Cheng, Nai-Ming, Fang, Tuan-Jen, Huang, Shiang-Fu, Lee, Li-Ang, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, Liao, Chun-Ta
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 25.10.2024; BioMed Central; BMC
• Subjects: Adjuvant therapy; Adjuvant treatment; Adult; Aged; Cancer; Cancer registry; Cancer therapies; Care and treatment; Chemoradiotherapy; Chemoradiotherapy, Adjuvant - methods; Chemotherapy; Comorbidity; Development and progression; Diagnosis; Disease; Dosage; Drug dosages; Extra-nodal extension; Extranodal Extension; Female; Head & neck cancer; Head and neck cancer; Humans; Lymphatic metastasis; Lymphatic system; Male; Medical prognosis; Metastasis; Middle Aged; Mouth Neoplasms - mortality; Mouth Neoplasms - pathology; Mouth Neoplasms - radiotherapy; Mouth Neoplasms - therapy; Oncology; Oral carcinoma; Oral cavity; Oral cavity squamous cell carcinoma; Patient outcomes; Patients; Prognosis; Radiation; Radiation therapy; Radiotherapy; Radiotherapy Dosage; Retrospective Studies; Review boards; Risk factors; Squamous cell carcinoma; Squamous Cell Carcinoma of Head and Neck - mortality; Squamous Cell Carcinoma of Head and Neck - radiotherapy; Squamous Cell Carcinoma of Head and Neck - therapy; Surgery; Survival outcomes; Taiwan - epidemiology; Taiwan; Survival outcomes; Extra-nodal extension; Cancer registry; Radiotherapy; Chemoradiotherapy; Oral cavity squamous cell carcinoma

The evidence for adjuvant chemoradiotherapy (CRT) of oral cavity squamous cell carcinoma (OCSCC) with extra-nodal extension (ENE) in National Comprehensive Cancer Network (NCCN) guidelines is derived from patients with head and neck cancer. The guidelines further suggest a radiation dose ranging fro...