The Effectiveness of Bivalent COVID-19 Vaccination: A Preliminary Report

• Published in: Life (Basel, Switzerland) Vol. 13; no. 10; p. 2094
• Main Authors: Chen, Ssu-Yu, Lin, Chien-Yu, Chi, Hsin, Weng, Shun-Long, Li, Sung-Tse, Tai, Yu-Lin, Huang, Ya-Ning, Huang, Hsiang, Lin, Chao-Hsu, Chiu, Nan-Chang
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.10.2023; MDPI
• Subjects: Antibodies; BA.1; bivalent; Clinical trials; Cohort analysis; Coronaviruses; COVID-19; COVID-19 vaccines; Effectiveness; Emergency medical care; Heterogeneity; Immunogenicity; Medical databases; mRNA vaccines; Observational studies; Pandemics; Proteins; SARS-CoV-2; Software; Systematic Review; updated vaccine; Vaccination; Vaccines; Taiwan; United States > US; COVID-19; updated vaccine; SARS-CoV-2; bivalent; BA.5; BA.1; vaccination

Vaccination has been a game-changer in the long battle against COVID-19. However, waning vaccine-induced immunity and the immune evasion of emerging variants create challenges. The rapid-fire development of bivalent vaccines (BVs), comprising ancestral strains and a new variant, was authorized to pr...