Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1) - Dwivedi, Yogesh; Rizavi, Hooriyah S.; Zhang, Hui; Roberts, Rosalinda C.; Conley, Robert R.; Pandey, Ghanshyam N. (The international journal of neuropsychopharmacology, 2009)
Keywords: Adult; Aged; Aged, 80 and over; Biomarkers - metabolism; Brain; Brain - enzymology; Brain - pathology; Catalytic Domain - physiology; Depressive Disorder, Major - enzymology; Depressive Disorder, Major - psychology; Down-Regulation - physiology; Female; Humans; Male; MAP Kinase Kinase 1 - biosynthesis; MAP Kinase Kinase 1 - metabolism; MAP Kinase Kinase 1 - physiology; MAP Kinase Signaling System - physiology; Middle Aged; Mitogen-Activated Protein Kinase 1 - biosynthesis; Mitogen-Activated Protein Kinase 1 - metabolism; Mitogen-Activated Protein Kinase 1 - physiology; Mitogen-Activated Protein Kinase 3 - biosynthesis; Mitogen-Activated Protein Kinase 3 - metabolism; Mitogen-Activated Protein Kinase 3 - physiology; Phosphorylation; Phosphorylation - physiology; Suicide - psychology; Suicides & suicide attempts; Up-Regulation - physiology; Young Adult; post-mortem brain; Depression; ERK kinase; ERK1/2 signalling; suicide