Endothelial function as a functional expression of cardiovascular risk factors

• Published in: Biomarkers in medicine Vol. 4; no. 3; pp. 351 - 360
• Main Authors: Reriani, Martin K, Lerman, Lilach O, Lerman, Amir
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.06.2010
• Subjects: atherosclerosis; Biomarkers; Biomarkers - metabolism; Blood vessels; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - etiology; Cellular biology; endothelial dysfunction; endothelium; Endothelium, Vascular - metabolism; Endothelium, Vascular - physiopathology; Humans; Physiological aspects; Risk Factors; surrogate marker; therapeutic end point; Vascular endothelium; vascular health; United States

Traditional cardiovascular risk (CV) factors based on the Framingham study have been used to estimate the risk of CV events and determine target cholesterol levels for primary prevention. Recently published systematic reviews have, however, demonstrated that the Framingham risk score is limited in c...