Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: a WHO-coordinated, prospective, international, observational cohort study

• Published in: The Lancet infectious diseases Vol. 18; no. 6; pp. 640 - 649
• Main Authors: Kleinschmidt, Immo, Bradley, John, Knox, Tessa Bellamy, Mnzava, Abraham Peter, Kafy, Hmooda Toto, Mbogo, Charles, Ismail, Bashir Adam, Bigoga, Jude D, Adechoubou, Alioun, Raghavendra, Kamaraju, Cook, Jackie, Malik, Elfatih M, Nkuni, Zinga José, Macdonald, Michael, Bayoh, Nabie, Ochomo, Eric, Fondjo, Etienne, Awono-Ambene, Herman Parfait, Etang, Josiane, Akogbeto, Martin, Bhatt, Rajendra M, Chourasia, Mehul Kumar, Swain, Dipak K, Kinyari, Teresa, Subramaniam, Krishanthi, Massougbodji, Achille, Okê-Sopoh, Mariam, Ogouyemi-Hounto, Aurore, Kouambeng, Celestin, Abdin, Mujahid Sheikhedin, West, Philippa, Elmardi, Khalid, Cornelie, Sylvie, Corbel, Vincent, Valecha, Neena, Mathenge, Evan, Kamau, Luna, Lines, Jonathan, Donnelly, Martin James
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.06.2018; Elsevier B.V; Elsevier Limited; Elsevier Science ;, The Lancet Pub. Group
• Subjects: Adolescent; Africa South of the Sahara - epidemiology; Analysis; Animals; Aquatic insects; Bioassays; Charities; Child; Child, Preschool; Children; Cohort analysis; Cohort Studies; Control; Culicidae - drug effects; Health risks; Households; Humans; Incidence; India - epidemiology; Infant; Infections; Infectious diseases; Insecticide Resistance; Insecticide-Treated Bednets; Insecticides; Internationality; Malaria; Malaria - epidemiology; Malaria - transmission; Medical personnel; Medical research; Mortality; Mosquito Control - methods; Mosquito Vectors - drug effects; Mosquitoes; Nets; Observational studies; Pesticide resistance; Phenotypes; Prospective Studies; Pyrethrins - pharmacology; Pyrethroids; Spraying; Studies; Vector-borne diseases; Workers; World Health Organization; Africa South of the Sahara; India; Benin; Cameroon; Kenya; Sudan; Africa

Scale-up of insecticide-based interventions has averted more than 500 million malaria cases since 2000. Increasing insecticide resistance could herald a rebound in disease and mortality. We aimed to investigate whether insecticide resistance was associated with loss of effectiveness of long-lasting...