Prognostic factors and risk-stratification model of recurrent or metastatic head and neck squamous cell carcinoma treated with cetuximab containing regimen

• Published in: BMC cancer Vol. 24; no. 1; pp. 1227 - 11
• Main Authors: Yang, Muh-Hwa, Chen, Tien-Hua, Wang, Hung-Ming, Hsieh, Jason Chia-Hsun, Huang, Huai-Cheng, Hsieh, Meng-Che, Yen, Chia-Jui, Wu, Shang-Yin, Hua, Chun-Hung, Lien, Ming-Yu, Chang, Yi-Fang, Wang, Hui-Ching, Chien, Chih-Yen, Huang, Tai-Lin, Lu, Hsueh-Ju, Lin, Jin-Ching, Wang, Chen-Chi, Liu, Yi-Chun, Chen, Jo-Pai, Lu, Wei-Chen, Yiu, Ching-Yi, Lin, Chien-Liang, Lou, Pei-Jen, Chu, Pen-Yuan
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.10.2024; BioMed Central; BMC
• Subjects: Adult; Aged; Alcohol; Alcohol use; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biochemistry; Blood cell count; Blood levels; Cancer; Cancer therapies; Care and treatment; Cell number; Cetuximab; Cetuximab - administration & dosage; Cetuximab - therapeutic use; Chemotherapy; Clinical outcomes; Drug development; Female; Head & neck cancer; Head and neck cancer; Head and neck carcinoma; Head and Neck Neoplasms - drug therapy; Head and Neck Neoplasms - mortality; Head and Neck Neoplasms - pathology; Head and neck squamous cell carcinoma; Health aspects; Hematology; Hemoglobin; Human papillomavirus; Humans; Induction therapy; Leukocytes (neutrophilic); Lymphocytes; Male; Medical centers; Medical prognosis; Medical research; Medicine, Experimental; Metastases; Metastasis; Middle Aged; Monoclonal antibodies; Multivariate analysis; Neoplasm Recurrence, Local; Neutrophils; Patients; Population studies; Prediction models; Prevention; Prognosis; Prognostic factor; Radiation therapy; Radiotherapy; Relapse; Response rates; Retrospective Studies; Risk Assessment - methods; Risk Factors; Risk groups; Risk-stratification model; Squamous cell carcinoma; Squamous Cell Carcinoma of Head and Neck - drug therapy; Squamous Cell Carcinoma of Head and Neck - mortality; Squamous Cell Carcinoma of Head and Neck - pathology; Statistical significance; Surgery; Survival analysis; Taiwan - epidemiology; Targeted cancer therapy; Variables; Taiwan; Prognostic factor; Head and neck squamous cell carcinoma; Cetuximab; Risk-stratification model

In recent years, the addition of cetuximab to chemotherapy has improved treatment outcomes for patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). In this study, we present the real-world survival data of R/M HNSCC patients who received cetuximab-containing regimens...