Role of the Interventional Radiologist in the Treatment of Desmoid Tumors

• Published in: Life (Basel, Switzerland) Vol. 13; no. 3; p. 645
• Main Authors: Goldberg, Daniel, Woodhead, Gregory, Hannallah, Jack, Young, Shamar
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26.02.2023; MDPI
• Subjects: Abdomen; Ablation; Acids; Care and treatment; cryoablation; Cytotoxicity; desmoid tumor; Drug therapy; Electric fields; Ethanol; Evidence-based medicine; Fibromas; Health aspects; Magnetic resonance imaging; Methods; microwave ablation; Morbidity; Mutation; Necrosis; Patients; Pazopanib; Quality of life; Radiation; Radiation therapy; radiofrequency ablation; Radiology, Interventional; Radiotherapy; Review; Soft tissues; Sulindac; Surgery; Surgical outcomes; Tomography; transarterial chemoembolization; Tumors; Ultrasonic imaging; United States; HIFU; cryoablation; microwave ablation; ablation; radiofrequency ablation; transarterial chemoembolization; desmoid tumor
• ISSN: 2075-1729; 2075-1729
• DOI: 10.3390/life13030645

Desmoid tumors are locally aggressive soft tissue tumors with variable clinical presentation. As is the case with most relatively rare tumors, a multidisciplinary team approach is required to best manage these patients. Surgical resection, systemic therapy, and radiation therapy have classically been mainstays of treatment for desmoid tumors; however, a more conservative "wait-and-see" approach has been adopted given their high recurrence rates and significant morbidity associated with the aforementioned therapies. Given the challenges of classical treatment methods, interventional radiologists have begun to play a significant role in minimally invasive interventions for desmoid tumors. Herein, the authors review imaging characteristics of desmoid tumors, current management recommendations, and minimally invasive therapeutic intervention options.