Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance - Bigio, Benedetta; Mathé, Aleksander A.; Sousa, Vasco C.; Zelli, Danielle; Svenningsson, Per; McEwen, Bruce S.; Nasca, Carla (Proceedings of the National Academy of Sciences - PNAS, 2016)
Keywords: Acetylcarnitine - pharmacology; Acetylcarnitine - therapeutic use; Animals; Antidepressants; Antidepressive Agents - pharmacology; Antidepressive Agents - therapeutic use; Biological Sciences; Dentate Gyrus - drug effects; Dentate Gyrus - metabolism; Depression - complications; Depression - drug therapy; Depression - genetics; Disease Models, Animal; Drug Resistance - genetics; Energy Metabolism - drug effects; Epigenesis, Genetic; Epigenetics; Fatty acids; Gene Expression Profiling; Genotype & phenotype; Hyperglycemia - complications; Hyperinsulinism - complications; Insulin resistance; Male; Mental depression; Overflow; Psychopathology; Rats; Rodents; Stress, Psychological; acetylcarnitine; dentate gyrus; insulin; RNAseq; metabolic factors