Clinical and immunological characteristics of high-risk double-hit multiple myeloma - Shang, Yufeng; Chen, Guopeng; Liu, Li; Pan, Ruiyang; Li, Xinqi; Shen, Hui; Tan, Yuxin; Ma, Linlu; Tong, Xiqin; Wang, Weida; Chen, Xiaoqin; Xia, Zhongjun; et al. (BMC cancer, 2024)
Keywords: Adenosine; ADP-ribosyl Cyclase 1 - metabolism; Adult; Aged; Analysis; Apoptosis; Bone marrow; Bone Marrow - immunology; Bone Marrow - pathology; Bone marrow immune microenvironment; Care and treatment; CD38 antigen; CD8 antigen; CD8-Positive T-Lymphocytes - immunology; Cell culture; Cell differentiation; Cell proliferation; Cytogenetics; Cytokines; Development and progression; Double-hit multiple myeloma; Female; Flow cytometry; Health aspects; Humans; Immunophenotyping; Interleukin 10; Interleukin-10 - metabolism; Lymphocytes; Lymphocytes T; Male; Medical prognosis; Middle Aged; Monoclonal antibodies; Multiple myeloma; Multiple Myeloma - immunology; Multiple Myeloma - pathology; Pathogenesis; PD-1; PD-1 protein; Plasma; Plasma Cells - immunology; Plasma Cells - metabolism; Plasma Cells - pathology; Prognosis; Retrospective Studies; T-Lymphocytes, Regulatory - immunology; TGF-β1; Transforming Growth Factor beta1 - metabolism; Transforming growth factor-b1; Transforming growth factors; Tregs; Tumor necrosis factor-TNF; China; TGF-β1; Bone marrow immune microenvironment; Double-hit multiple myeloma; PD-1; Tregs