Search for Microorganisms in Men with Urologic Chronic Pelvic Pain Syndrome: A Culture-Independent Analysis in the MAPP Research Network

• Published in: The Journal of urology Vol. 194; no. 1; pp. 127 - 135
• Main Authors: Nickel, J. Curtis, Stephens, Alisa, Landis, J. Richard, Chen, Jun, Mullins, Chris, van Bokhoven, Adrie, Lucia, M. Scott, Melton-Kreft, Rachael, Ehrlich, Garth D
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2015
• Subjects: Bacteria - isolation & purification; chronic pain; Humans; infection; Male; microbiota; pelvic pain; prostatitis; Prostatitis - microbiology; Prostatitis - urine; Urinalysis; Urology; microbiota; infection; chronic pain; VB1; GUPI; voided bladder 2 or midstream urine (bladder) specimen; VB3; chronic prostatitis/chronic pelvic pain syndrome; Epidemiological/Phenotyping; VB2; IC/BPS; UCPPS; interstitial cystitis/bladder pain syndrome; prostatitis; FDR; Multidisciplinary Approach to the Study of Pelvic Pain; urologic chronic pelvic pain syndrome; IC; voided bladder 3 or post-prostatic massage urine (prostate) specimen; CPSI; false discovery rate; interstitial cystitis; polymerase chain reaction; CP/CPPS; Chronic Prostatitis Symptom Index; EP; CP; chronic prostatitis; Genitourinary Pain Index; voided bladder 1 or initial stream urine (urethral) specimen; MAPP; pelvic pain; PCR

Purpose We used next-generation, state-of-the-art, culture independent methodology to survey urine microbiota of males with urologic chronic pelvic pain syndrome and control participants enrolled in the MAPP Network to investigate a possible microbial etiology. Materials and Methods Male patients wi...