Development of an Immunochromatography Assay to Detect Marburg Virus and Ravn Virus

• Published in: Viruses Vol. 15; no. 12; p. 2349
• Main Authors: Changula, Katendi, Kajihara, Masahiro, Muramatsu, Shino, Hiraoka, Koji, Yamaguchi, Toru, Yago, Yoko, Kato, Daisuke, Miyamoto, Hiroko, Mori-Kajihara, Akina, Shigeno, Asako, Yoshida, Reiko, Henderson, Corey W., Marzi, Andrea, Takada, Ayato
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29.11.2023
• Subjects: Animals; Antibodies, Monoclonal; Antigens; blood serum; Chromatography, Affinity; Diagnosis; Ebola virus; Epidemics; Equatorial Guinea; Fever; filovirus; Ghana; Guinea; Health aspects; Identification and classification; immunoaffinity chromatography; Immunoassay; Infections; Infectious diseases; Laboratory animals; Marburg disease; Marburg marburgvirus; Marburg virus; Marburg Virus Disease; Marburgvirus; MARV; Methods; Monoclonal antibodies; monoclonal antibody; nucleoprotein; Nucleoproteins; Outbreaks; Plasmids; point-of-care testing; Ravn virus; RNA polymerase; RNA viruses; Tanzania; Tissue culture; Viruses; Japan; Angola; Ghana; Guinea; Equatorial Guinea; Tanzania; RDT; Ravn virus; Marburg virus; immunochromatography assay; nucleoprotein; diagnosis; rapid diagnostic test; MARV; monoclonal antibody; filovirus

The recent outbreaks of Marburg virus disease (MVD) in Guinea, Ghana, Equatorial Guinea, and Tanzania, none of which had reported previous outbreaks, imply increasing risks of spillover of the causative viruses, Marburg virus (MARV) and Ravn virus (RAVV), from their natural host animals. These outbr...