Screening targeted testis-specific genes for molecular assessment of aberrant sperm quality

• Published in: Molecular medicine reports Vol. 14; no. 2; pp. 1594 - 1600
• Main Authors: Liu, Xue Xia, Shen, Xiao Fang, Liu, Fu-Jun
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.08.2016; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Adult; Binding sites; Bioinformatics; Biomarkers; Cell cycle; Chromosomes; Computational Biology - methods; Databases, Nucleic Acid; Diagnosis; Epididymis; Families & family life; Gene Expression; Genetic aspects; Genetic Association Studies; Genomes; Genotype; Heat shock proteins; HSP70 Heat-Shock Proteins - genetics; HSP70 Heat-Shock Proteins - metabolism; Hsp70 protein; Humans; Identification and classification; Immunohistochemistry; Infertility; Infertility, Male; Infertility, Male - genetics; Information systems; Localization; Male; male infertility; Medical research; Medical screening; Mens health; Metabolism; Metabolites; Molecular diagnostic techniques; Motility; Phosphoglycerate kinase; Proteins; Proteome; Proteomics - methods; Quality; Sperm; sperm quality; Spermatogenesis; Spermatozoa; Spermatozoa - physiology; Teratozoospermia - genetics; Testes; testis; Testis - metabolism; Young adults; United States > US

Teratospermia is a heterogeneous and complex disorder, which is closely associated with male fertility. Genes and gene products associated with teratospermia may serve as targeted biomarkers that help understand the underlying mechanisms of male infertility; however, systematic information on the su...