Effects of sodium ferulate on preventing steroid-induced femoral head osteonecrosis in rabbits

• Published in: Journal of Zhejiang University. B. Science Vol. 14; no. 5; pp. 426 - 437
• Main Authors: Tian, Lei, Dang, Xiao-qian, Wang, Chun-sheng, Yang, Pei, Zhang, Chen, Wang, Kun-zheng
• Format: Journal Article
• Language: English
• Published: Heidelberg SP Zhejiang University Press 01.05.2013; Springer Nature B.V; Zhejiang University Press
• Subjects: Animals; Anti-Inflammatory Agents, Non-Steroidal - administration & dosage; Apoptosis; Apoptosis - drug effects; Biomedical and Life Sciences; Biomedicine; Coumaric Acids - administration & dosage; Disease Models, Animal; Drug Interactions; Femur Head Necrosis - chemically induced; Femur Head Necrosis - pathology; Femur Head Necrosis - prevention & control; Humans; Male; Methylprednisolone; Rabbits; Treatment Outcome; Rabbit; Sodium ferulate; Femoral head necrosis; R684.3; Glucocorticoid; Apoptosis

The aim of this study is to investigate the effects and possible mechanisms of sodium ferulate （SF） on anti-apoptosis in steroid-induced femoral head osteonecrosis in rabbits. Japanese white rabbits were randomly divided into three groups （control group, treatment group, and model group）, each with...