Impact of liver fibrosis on prognosis following liver resection for hepatitis B-associated hepatocellular carcinoma

• Published in: British journal of cancer Vol. 109; no. 3; pp. 573 - 581
• Main Authors: Wang, Q, Fiel, M I, Blank, S, Luan, W, Kadri, H, Kim, K W, Manizate, F, Rosenblatt, A G, Labow, D M, Schwartz, M E, Hiotis, S P
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 06.08.2013; Nature Publishing Group
• Subjects: 692/699/1503/1607/1605; 692/699/67/1504/1610; 692/700/1750; 692/700/565/545; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Cancer Research; Carcinoma, Hepatocellular - pathology; Carcinoma, Hepatocellular - surgery; Carcinoma, Hepatocellular - virology; Cirrhosis; Clinical Study; Drug Resistance; Epidemiology; Female; Gastroenterology. Liver. Pancreas. Abdomen; Hepatitis B; Hepatitis B, Chronic - pathology; Humans; Liver cancer; Liver cirrhosis; Liver Cirrhosis - pathology; Liver Cirrhosis - virology; Liver Neoplasms - pathology; Liver Neoplasms - surgery; Liver Neoplasms - virology; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Magnetic resonance imaging; Male; Medical prognosis; Medical research; Medical sciences; Middle Aged; Molecular Medicine; Multiple tumors. Solid tumors. Tumors in childhood (general aspects); Neoplasm Recurrence, Local - pathology; Neoplasm Recurrence, Local - virology; Oncology; Other diseases. Semiology; Patients; Prognosis; Tumors; Young Adult; New York; United States > US; Ishak stage; hepatitis B; prognosis; resection; hepatocellular carcinoma; Hepatic fibrosis; Prognosis; Hepatic disease; Hepatocellular carcinoma; Surgical resection; Malignant tumor; Infection; Viral hepatitis B; Liver cancer; Clinical stage; Cancerology; Treatment; Surgery; Viral disease; Digestive diseases; Cancer

Background: This study aims to evaluate the impact of liver fibrosis severity on prognosis following liver resection among HBV–HCC patients. Methods: Data were extracted from a prospective database of 189 HBV–HCC patients treated at Mount Sinai between 1995 and 2008. Fibrosis staging of each surgica...