Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy - Boumezbeur, Fawzi; Mason, Graeme F; de Graaf, Robin A; Behar, Kevin L; Cline, Gary W; Shulman, Gerald I; Rothman, Douglas L; Petersen, Kitt F (Journal of cerebral blood flow and metabolism, 2010)
Keywords: Adult; Aged; Aging - physiology; Aspartic Acid - analogs & derivatives; Aspartic Acid - metabolism; Biological and medical sciences; Brain - anatomy & histology; Brain Chemistry - physiology; Female; Glucose Tolerance Test; Glutamic Acid - metabolism; Humans; Image Processing, Computer-Assisted; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Medical sciences; Mitochondria - metabolism; Nervous system; Neurology; Original; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Vascular diseases and vascular malformations of the nervous system; human brain; metabolism; aging; mitochondria; 1H MRS; 13C MRS; Human; Nervous system diseases; Senescence; NMR spectrometry; Metabolism; C MRS; Cerebral disorder; Encephalon; H MRS; Mitochondria; Central nervous system disease; Cerebrovascular disease