Radiation dose evaluation of pediatric patients in CT brain examination: multi-center study

• Published in: Scientific reports Vol. 11; no. 1; pp. 4663 - 6
• Main Authors: Eddy, Fotso Kamdem, Ngano, Samba Odette, Jervé, Fotue Alain, Serge, Abogo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 25.02.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/57; 631/67; 639/766; Adolescent; Brain - diagnostic imaging; Child; Child, Preschool; Children; Computed tomography; Dose-response effects; Hospitals; Humanities and Social Sciences; Humans; Infant; Medical imaging; multidisciplinary; Patients; Pediatrics; Quality control; Radiation Dosage; Radiation protection; Science; Science (multidisciplinary); Tomography; Tomography, X-Ray Computed - methods; France; Cameroon
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-021-84078-z

There is currently no Pediatric Regulatory Diagnostic Reference Level (DRL) in Cameroon to standardize protocols in hospitals. France, a European country, has DRL allowing them to optimize their examination protocol. For the sake of radiation protection, we have proposed to evaluate the dose and acquisition parameters delivered to our pediatric patients to optimize the protocols used. We also compared the 75th percentile values of dose parameters by acquisition between the three hospitals to Diagnostic Reference Level (DRL) of France. In this retrospective and evaluative multicenter study, a total of 320 patients who had at least one cranial CT scan were enrolled from three medical centers. The CT acquisition parameters including tube potential (kV), tube current (mA), slice Thickness (T), spiral or sequential scanning techniques, volume CT dose index (CTDIvol), and dose length product (DLP) were analyzed. CTDIvol values in our centers were found up to 17.42%, 46.01%, 21.56% respectively for children aged 1–4 higher than values of France's DRL. For those aged 5–9, we obtained 44.58%, 43.15%, 42.21% respectively. In addition, for children aged 10–14 there are also up to 47.73%, 44.11%, 46.39% respectively higher than values of France's DRL. It is similary for DLP values. The study showed a significant dosimetric overshoot compared to the France’s DRL and prompted us to make corrections to the protocols used and to a more rigorous monitoring of the principles of radiation protection and optimization rules in pediatric computed tomography in our hospitals. Our results have led us to make changes to our protocols which are the subject of a new dosimetric evaluation. The development of DRL for improving the pediatric CT scan in our country is necessary to optimize our protocols. Our results have led us to make changes to our protocols which are the subject of a new dosimetric evaluation. It would be necessary to set up a quality control structure in Cameroon and their applications in current practice.