Analysis of the brain mural cell transcriptome

• Published in: Scientific reports Vol. 6; no. 1; p. 35108
• Main Authors: He, Liqun, Vanlandewijck, Michael, Raschperger, Elisabeth, Andaloussi Mäe, Maarja, Jung, Bongnam, Lebouvier, Thibaud, Ando, Koji, Hofmann, Jennifer, Keller, Annika, Betsholtz, Christer
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 11.10.2016; Nature Publishing Group
• Subjects: 13/51; 14/32; 14/63; 38/39; 38/90; 631/378; 631/80; 692/699/75; Animals; Brain; Brain - cytology; Data interpretation; Flow Cytometry; Fluorescence in situ hybridization; Gene expression; Gene Expression Profiling; Genes; Glial cells; Humanities and Social Sciences; Immunohistochemistry; Interferon; Mice; Microvasculature; Microvessels - cytology; multidisciplinary; Pericytes; Pericytes - physiology; Ribonucleic acid; RNA; Rodents; Science; Sequence Analysis, RNA; Staining and Labeling; Transgenic mice; Vitronectin

Pericytes, the mural cells of blood microvessels, regulate microvascular development and function and have been implicated in many brain diseases. However, due to a paucity of defining markers, pericyte identification and functional characterization remain ambiguous and data interpretation problemat...