Conformal piezoelectric systems for clinical and experimental characterization of soft tissue biomechanics

• Published in: Nature materials Vol. 14; no. 7; pp. 728 - 736
• Main Authors: Dagdeviren, Canan, Shi, Yan, Joe, Pauline, Ghaffari, Roozbeh, Balooch, Guive, Usgaonkar, Karan, Gur, Onur, Tran, Phat L., Crosby, Jessi R., Meyer, Marcin, Su, Yewang, Chad Webb, R., Tedesco, Andrew S., Slepian, Marvin J., Huang, Yonggang, Rogers, John A.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.07.2015; Nature Publishing Group; Springer Nature
• Subjects: 142/126; 639/301/1005/1007; 639/301/1005/1009; Adult; Aged; Animal models; Animals; Biological; Biomaterials; Biomechanical Phenomena; Biomechanics; Biosensors; Cattle; Condensed Matter Physics; Devices; Dynamical systems; Dynamics; Elasticity; Electronic devices; Electrophysiology - instrumentation; Electrophysiology - methods; Epidermis; Female; Humans; Keratinocytes - cytology; Male; MATERIALS SCIENCE; Mechanical properties; Medical treatment; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanostructures - chemistry; Nanotechnology; Nanotechnology - methods; Optical and Electronic Materials; Organs; Piezoelectricity; Sensors and biosensors; Skin - pathology; Stress, Mechanical; Texture; Tissues; Topography; Viscosity

Mechanical assessment of soft biological tissues and organs has broad relevance in clinical diagnosis and treatment of disease. Existing characterization methods are invasive, lack microscale spatial resolution, and are tailored only for specific regions of the body under quasi-static conditions. He...